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Outputs (1267)

Local origins impart conserved bone type-related differences in human osteoblast behaviour (2015)
Journal Article
Shah, M., Gburcik, V., Reilly, P., Sankey, R. A., Emery, R. J., Clarkin, C. E., & Pitsillides, A. A. (2015). Local origins impart conserved bone type-related differences in human osteoblast behaviour. https://doi.org/10.22203/eCM.v029a12

Osteogenic behaviour of osteoblasts from trabecular, cortical and subchondral bone were examined to determine any bone type-selective differences in samples from both osteoarthritic (OA) and osteoporotic (OP) patients. Cell growth, differentiation; a... Read More about Local origins impart conserved bone type-related differences in human osteoblast behaviour.

Matching times of leading and following suggest cooperation through direct reciprocity during V-formation flight in ibis (2015)
Journal Article
Voelkl, B., Portugal, S. J., Unsoeld, M., Usherwood, J. R., Wilson, A. M., & Fritz, J. (2015). Matching times of leading and following suggest cooperation through direct reciprocity during V-formation flight in ibis. https://doi.org/10.1073/pnas.1413589112

One conspicuous feature of several larger bird species is their annual migration in V-shaped or echelon formation. When birds are flying in these formations, energy savings can be achieved by using the aerodynamic up-wash produced by the preceding bi... Read More about Matching times of leading and following suggest cooperation through direct reciprocity during V-formation flight in ibis.

Is a standalone inertial measurement unit accurate and precise enough for quantification of movement symmetry in the horse? (2015)
Journal Article
Brighton, C., Olsen, E., & Pfau, T. (2015). Is a standalone inertial measurement unit accurate and precise enough for quantification of movement symmetry in the horse?. Computer Methods in Biomechanics and Biomedical Engineering, 18(5), 527-532. https://doi.org/10.1080/10255842.2013.819857

Standalone ‘low-cost’ inertial measurement units (IMUs) could facilitate large-scale studies into establishing minimal important differences (MID) for orthopaedic deficits (lameness) in horses. We investigated accuracy and limits of agreement (LoA) a... Read More about Is a standalone inertial measurement unit accurate and precise enough for quantification of movement symmetry in the horse?.

Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds (2015)
Journal Article
Regnault, S., Pitsillides, A. A., & Hutchinson, J. R. (2015). Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds. https://doi.org/10.7717/peerj.711

The patella (kneecap) exhibits multiple evolutionary origins in birds, mammals, and lizards, and is thought to increase the mechanical advantage of the knee extensor muscles. Despite appreciable interest in the specialized anatomy and locomotion of p... Read More about Structure, ontogeny and evolution of the patellar tendon in emus (Dromaius novaehollandiae) and other palaeognath birds.

Measuring Clinical Effectiveness of Medicinal Products for the Treatment of Duchenne Muscular Dystrophy (2015)
Journal Article
Lynn, S., Aartsma-Rus, A., Furlong, P., Goemans, N., De Luca, A., Mayhew, A., McDonald, C., Mercuri, E., Muntoni, F., Pohlschmidt, M., Verschuuren, J., Voit, T., Vroom, E., Wells, D. J., & Straub, V. (2015). Measuring Clinical Effectiveness of Medicinal Products for the Treatment of Duchenne Muscular Dystrophy. Neuromuscular Disorders, 25(1), 96-105. https://doi.org/10.1016/j.nmd.2014.09.003

Ontogenetic scaling patterns and functional anatomy of the pelvic limb musculature in emus (Dromaius novaehollandiae) (2014)
Journal Article
Lamas, L., Main, R. P., & Hutchinson, J. R. (2014). Ontogenetic scaling patterns and functional anatomy of the pelvic limb musculature in emus (Dromaius novaehollandiae). https://doi.org/10.7717/peerj.716

Emus (Dromaius novaehollandiae) are exclusively terrestrial, bipedal and cursorial ratites with some similar biomechanical characteristics to humans. Their growth rates are impressive, as their body mass increases eighty-fold from hatching to adultho... Read More about Ontogenetic scaling patterns and functional anatomy of the pelvic limb musculature in emus (Dromaius novaehollandiae).

Iodine vapor staining for atomic number contrast in backscattered electron and X-ray imaging (2014)
Journal Article
Boyde, A., McCorkell, F. A., Taylor, G. K., Bomphrey, R. J., & Doube, M. (2014). Iodine vapor staining for atomic number contrast in backscattered electron and X-ray imaging. Microscopy Research and Technique, 77(12), 1044-1051. https://doi.org/10.1002/jemt.22435

Iodine imparts strong contrast to objects imaged with electrons and X‐rays due to its high atomic number (53), and is widely used in liquid form as a microscopic stain and clinical contrast agent. We have developed a simple technique which exploits e... Read More about Iodine vapor staining for atomic number contrast in backscattered electron and X-ray imaging.

Mitigating the Goldilocks effect: the effects of different substrate models on track formation potential (2014)
Journal Article
Falkingham, P. L., Hage, J., & Baeker, M. (2014). Mitigating the Goldilocks effect: the effects of different substrate models on track formation potential. Royal Society Open Science, 1(3), 140225. https://doi.org/10.1098/rsos.140225

In ichnology, the Goldilocks effect describes a scenario in which a substrate must be ‘just right’ in order for tracks to form—too soft, the animal will be unable to traverse the area, and too firm, the substrate will not deform. Any given substrate... Read More about Mitigating the Goldilocks effect: the effects of different substrate models on track formation potential.

Don't break a leg: Running birds from quail to ostrich prioritise leg safety and economy in uneven terrain (2014)
Journal Article
Birn-Jeffery, A. V., Hubicki, C. M., Blum, Y., Renjewski, D., Hurst, J. W., & Daley, M. A. (2014). Don't break a leg: Running birds from quail to ostrich prioritise leg safety and economy in uneven terrain. Journal of Experimental Biology, 217(Pt21), 3786-96. https://doi.org/10.1242/jeb.102640

Cursorial ground birds are paragons of bipedal running that span a 500-fold mass range from quail to ostrich. Here we investigate the task-level control priorities of cursorial birds by analysing how they negotiate single-step obstacles that create a... Read More about Don't break a leg: Running birds from quail to ostrich prioritise leg safety and economy in uneven terrain.

Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes (2014)
Journal Article
Fernandez-Fuente, M., Terracciano, C. M., Martin-Duque, P., Brown, S. C., Vassaux, G., & Piercy, R. J. (2014). Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes. PLoS ONE, 9(8), e105971. https://doi.org/10.1371/journal.pone.0105971

Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malig... Read More about Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes.

Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations (2014)
Journal Article
Soper, R. J., Oguz, C., Emery, R., Pitsillides, A. A., & Hodges, S. J. (2014). Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations. Molecular Nutrition & Food Research, 58(8), 1658-1666. https://doi.org/10.1002/mnfr.201400063

The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitam... Read More about Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations.

Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size (2014)
Journal Article
Tickle, P. G., Paxton, H. P., Rankin, J. W., Hutchinson, J. R., & Codd, J. R. (2014). Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size. https://doi.org/10.7717/peerj.432

Genetic selection for improved meat yields, digestive efficiency and growth rates have transformed the biology of broiler chickens. Modern birds undergo a 50-fold multiplication in body mass in just six weeks, from hatching to slaughter weight. Howev... Read More about Anatomical and biomechanical traits of broiler chickens across ontogeny. Part I. Anatomy of the musculoskeletal respiratory apparatus and changes in organ size.

Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb (2014)
Journal Article
Hutchinson, J. R., Paxton, H. P., Codd, J., Rankin, J. W., & Tickle, P. (2014). Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb. https://doi.org/10.7717/peerj.473

In broiler chickens, genetic success for desired production traits is often shadowed by welfare concerns related to musculoskeletal health. Whilst these concerns are clear, a viable solution is still elusive. Part of the solution lies in knowing how... Read More about Anatomical and biomechanical traits of broiler chickens across ontogeny. Part II. Body segment inertial properties and muscle architecture of the pelvic limb.