Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK
Journal Article
Wieland, B., Werling, D., Nevel, M., Grierson, S., Rycroft, A. N., Demmers, T. G. M., Cook, A. J. C., Done, S. H., Armstrong, D., & Wathes, C. M. Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK. Veterinary Record, 170(23), 596+. https://doi.org/10.1136/vr.100276
Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level
Journal Article
Alarcon, P., Velasova, M., Werling, D., Staerk, K. D. C., Chang, Y. M., Nevel, M., Pfeiffer, D. U., & Wieland, B. Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level. Preventive Veterinary Medicine, 98(1), 19-28. https://doi.org/10.1016/j.prevetmed.2010.09.022
TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Presentation / Conference Contribution
Allenspach, K., Kathrani, A., House, A. K., Holder, A. L., Catchpole, B., & Werling, D. TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines
Journal Article
Burgos, R. A., Conejeros, I., Hidalgo, M. A., Werling, D., & Hermosilla, C. Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines. Veterinary Immunology and Immunopathology, 143(1-2), 1-10. https://doi.org/10.1016/j.vetimm.2011.05.037
Therapeutic targeting of the innate immune system in domestic animals
Journal Article
Coffey, T. J., & Werling, D. Therapeutic targeting of the innate immune system in domestic animals. Cell and Tissue Research, 343(1), 251-261. https://doi.org/10.1007/s00441-010-1054-9
Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent
Journal Article
Conejeros, I., Patterson, R., Burgos, R. A., Hermosilla, C., & Werling, D. Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent. Veterinary Immunology and Immunopathology, 139(2-4), 308-312. https://doi.org/10.1016/j.vetimm.2010.10.021
Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways
Journal Article
Gibson, A. J., Larsson, J., Bateman, M., Brownlie, J., & Werling, D. Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways. Journal of Virology, 85(7), 3695-3697. https://doi.org/10.1128/jvi.02626-10
Toll-like receptors in domestic animals
Journal Article
Jungi, T. W., Farhat, K., Burgener, I. A., & Werling, D. Toll-like receptors in domestic animals. Cell and Tissue Research, 343(1), 107-120. https://doi.org/10.1007/s00441-010-1047-8
Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x
POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
Presentation / Conference Contribution
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A. M., & Allenspach, K. POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010
Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380
MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
Presentation / Conference Contribution
Kathrani, A., Werling, D., & Allenspach, K. MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN
Presentation / Conference Contribution
Kathrani, A., Werling, D., Holder, A. L., Catchpole, B., & Allenspach, K. POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN
Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1
Journal Article
Willcocks, S., Offord, V., Seyfert, H. M., Coffey, T., & Werling, D. Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1. Journal of Leukocyte Biology, 94(3), 449-58. https://doi.org/10.1189/jlb.0812390
Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction. American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534
Primary bovine colonic cells: A model to study strain-specific responses to Escherichia coli
Journal Article
Bridger, P. S., Mohr, M., Stamm, I., Frohlich, J., Follmann, W., Birkner, S., Metcalfe, H., Werling, D., Baljer, G., & Menge, C. Primary bovine colonic cells: A model to study strain-specific responses to Escherichia coli. Veterinary Immunology and Immunopathology, 137(1-2), 54-63. https://doi.org/10.1016/j.vetimm.2010.04.010
TGF-b2 induction regulates invasiveness of Theileria-Transformed Leukocytes and Disease susceptibility
Journal Article
Chaussepied, M., Janski, N., Baumgartner, M., Lizundia, R., Jensen, K., Weri, W., Shiels, B. R., Weitzmn, J. B., Glass, E. J., Werling, D., & Langsley, G. TGF-b2 induction regulates invasiveness of Theileria-Transformed Leukocytes and Disease susceptibility. PLoS Pathogens, 6(11), e1001197. https://doi.org/10.1371/journal.ppat.1001197
Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies
Journal Article
Allenspach, K., House, A., Smith, K., McNeill, F. M., Hendricks, A., Elson-Riggins, J. G., Riddle, A. L., Steiner, J. M., Werling, D., Garden, O. A., Catchpole, B., & Suchodolski, J. S. Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Veterinary Microbiology, 146(3-4), 326-335. https://doi.org/10.1016/j.vetmic.2010.05.025
Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO)
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO). American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534