Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages
Journal Article
Burr, S., Thomas, C. J., Brownlie, J., Offord, V., Coffey, T. J., & Werling, D. Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages. Veterinary Immunology and Immunopathology, 150(1-2), 123-127. https://doi.org/10.1016/j.vetimm.2012.08.009
Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease
Journal Article
Dakin, S. G., Dudhia, J., Werling, N. J., Werling, D., Abayasekara, D. R. E., & Smith, R. K. W. Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease. PLoS ONE, 7(11), e48978. https://doi.org/10.1371/journal.pone.0048978
Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair
Journal Article
Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R. E., Young, N. J., Smith, R. K. W., & Dudhia, J. Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS ONE, 7(2), e32333. https://doi.org/10.1371/journal.pone.0032333
Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response
Journal Article
Gibson, A. J., Miah, S., Griebel, P., Brownlie, J., & Werling, D. Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response. Developmental and Comparative Immunology, 36(2), 332-341. https://doi.org/10.1016/j.dci.2011.05.002
TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin
Journal Article
Kathrani, A., Holder, A. L., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., & Allenspach, K. TLR5 Risk-Associated Haplotype for Canine Inflammatory Bowel Disease Confers Hyper-Responsiveness to Flagellin. PLoS ONE, 7(1), e30117. https://doi.org/10.1371/journal.pone.0030117
Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex
Journal Article
Pagano, S., Satta, N., Werling, D., Offord, V., DeMoerloose, P., Charbonney, E., Hochstrasser, D., Roux-Lombard, P., & Vuilleumier, N. Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. Journal of Internal Medicine, 272(4), 344-357. https://doi.org/10.1111/j.1365-2796.2012.02530.x
Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease
Journal Article
Schmitz, S., Garden, O. G., Werling, D., & Allenspach, K. Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease. Veterinary Immunology and Immunopathology, 146(1), 87-91. https://doi.org/10.1016/j.vetimm.2012.01.013
Adaptive evolution of Toll-like receptor 5 in domesticated mammals
Journal Article
Smith, S. A., Jann, O. C., Haig, D., Russell, G. C., Werling, D., Glass, E. J., & Emes, R. D. Adaptive evolution of Toll-like receptor 5 in domesticated mammals. BMC Evolutionary Biology, 12, Online. https://doi.org/10.1186/1471-2148-12-122
Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK
Journal Article
Wieland, B., Werling, D., Nevel, M., Grierson, S., Rycroft, A. N., Demmers, T. G. M., Cook, A. J. C., Done, S. H., Armstrong, D., & Wathes, C. M. Porcine circovirus type 2 infection before and during an outbreak of postweaning multisystemic wasting syndrome on a pig farm in the UK. Veterinary Record, 170(23), 596+. https://doi.org/10.1136/vr.100276
Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level
Journal Article
Alarcon, P., Velasova, M., Werling, D., Staerk, K. D. C., Chang, Y. M., Nevel, M., Pfeiffer, D. U., & Wieland, B. Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level. Preventive Veterinary Medicine, 98(1), 19-28. https://doi.org/10.1016/j.prevetmed.2010.09.022
TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Presentation / Conference Contribution
Allenspach, K., Kathrani, A., House, A. K., Holder, A. L., Catchpole, B., & Werling, D. TOLL-LIKE RECEPTOR 5 MUTATIONS IN GERMAN SHEPHERD DOGS ARE HYPER-RESPONSIVE TO STIMULATION WITH FLAGELLIN
Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines
Journal Article
Burgos, R. A., Conejeros, I., Hidalgo, M. A., Werling, D., & Hermosilla, C. Calcium influx, a new potential therapeutic target in the control of neutrophil-dependent inflammatory diseases in bovines. Veterinary Immunology and Immunopathology, 143(1-2), 1-10. https://doi.org/10.1016/j.vetimm.2011.05.037
Therapeutic targeting of the innate immune system in domestic animals
Journal Article
Coffey, T. J., & Werling, D. Therapeutic targeting of the innate immune system in domestic animals. Cell and Tissue Research, 343(1), 251-261. https://doi.org/10.1007/s00441-010-1054-9
Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent
Journal Article
Conejeros, I., Patterson, R., Burgos, R. A., Hermosilla, C., & Werling, D. Induction of reactive oxygen species in bovine neutrophils to CD11b, but not dectin-1-dependent. Veterinary Immunology and Immunopathology, 139(2-4), 308-312. https://doi.org/10.1016/j.vetimm.2010.10.021
Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways
Journal Article
Gibson, A. J., Larsson, J., Bateman, M., Brownlie, J., & Werling, D. Bovine Viral Diarrhea Virus Strain- and Cell Type-Specific Inhibition of Type I Interferon Pathways. Journal of Virology, 85(7), 3695-3697. https://doi.org/10.1128/jvi.02626-10
Toll-like receptors in domestic animals
Journal Article
Jungi, T. W., Farhat, K., Burgener, I. A., & Werling, D. Toll-like receptors in domestic animals. Cell and Tissue Research, 343(1), 107-120. https://doi.org/10.1007/s00441-010-1047-8
Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x
POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
Presentation / Conference Contribution
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A. M., & Allenspach, K. POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010
Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380