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Heterozygosity for P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog (2017)
Journal Article
Flores, R. S., Boudreaux, M. K., Vasquez, B., Bristow, P. C., Aronson, L. R., Santoro-Beer, K., & Callan, M. B. (2017). Heterozygosity for P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog. Veterinary Clinical Pathology, 46(4), 569-574. https://doi.org/10.1111/vcp.12533

A 3‐year‐old, female Greater Swiss Mountain dog developed a hemoperitoneum following an exploratory laparotomy and ovariohysterectomy. Platelet count, PT, APTT, and plasma von Willebrand factor antigen concentration were within RIs. A buccal mucosal... Read More about Heterozygosity for P2Y12 receptor gene mutation associated with postoperative hemorrhage in a Greater Swiss Mountain dog.

Direct activation of NADPH oxidase 2 by 2-deoxyribose-1-phosphate triggers nuclear factor kappa B-dependent angiogenesis. (2017)
Journal Article
Vara, D., Watt, J. M., Fortunato, T. M., Mellor, H., Burgess, M., Wicks, K., Mace, K., Reeksting, S., Lubben, A. T., Wheeler-Jones, C. P. D., & Pula, G. (2017). Direct activation of NADPH oxidase 2 by 2-deoxyribose-1-phosphate triggers nuclear factor kappa B-dependent angiogenesis. https://doi.org/10.1089/ars.2016.6869

AbstractAims: Deoxyribose-1-phosphate (dRP) is a proangiogenic paracrine stimulus released by cancer cells, platelets, and macrophages and acting on endothelial cells. The objective of this study was to clarify how dRP stimulates angiogenic responses... Read More about Direct activation of NADPH oxidase 2 by 2-deoxyribose-1-phosphate triggers nuclear factor kappa B-dependent angiogenesis..

Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat (2017)
Journal Article
Heaps, L. A., Scudder, C. J., Lipscomb, V. J., Steinbach, S. M. L., Priestnall, S. L., Martineau, H., Szladovits, B., Fowkes, R. C., & Garden, O. A. (2017). Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat. Journal of Feline Medicine and Surgery Open Reports, 32(2), https://doi.org/10.1177/2055116917722701

The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles (2017)
Journal Article
Shearer, T., Thorpe, C. T., & Screen, H. R. C. (2017). The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles. https://doi.org/10.1098/rsif.2017.0261

A nonlinear elastic microstructural model is used to investigate the relationship between structure and function in energy-storing and positional tendons. The model is used to fit mechanical tension test data from the equine common digital extensor t... Read More about The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles.

Endothelial SHIP2 suppresses Nox2 NADPH oxidase-dependent vascular oxidative stress, endothelial dysfunction and systemic insulin resistance (2017)
Journal Article
Watt, N. T., Gage, M. C., Patel, P. A., Viswambharan, H., Sukumar, P., Galloway, S., Yuldasheva, N. Y., Imrie, H., Walker, A. M. N., Griffin, K. J., Makava, N., Skromna, A., Bridge, K., Beech, D. J., Schurmans, S., Wheatcroft, S. B., Kearney, M. T., & Cubbon, R. M. (2017). Endothelial SHIP2 suppresses Nox2 NADPH oxidase-dependent vascular oxidative stress, endothelial dysfunction and systemic insulin resistance. Diabetes, 66(11), 2808-2821. https://doi.org/10.2337/db17-0062

Shc homology 2–containing inositol 5′ phosphatase-2 (SHIP2) is a lipid phosphatase that inhibits insulin signaling downstream of phosphatidylinositol 3-kinase (PI3K); its role in vascular function is poorly understood. To examine its role in endothel... Read More about Endothelial SHIP2 suppresses Nox2 NADPH oxidase-dependent vascular oxidative stress, endothelial dysfunction and systemic insulin resistance.

Assessing the effects of the first 2 years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle in 2013–2015 (2017)
Journal Article
Brunton, L. A., Donnelly, C. A., O'Connor, H. M., Prosser, A., Ashfield, S., Ashton, A., Upton, P., Mitchell, A., Goodchild, A. V., Parry, J. E., & Downs, S. H. (2017). Assessing the effects of the first 2 years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle in 2013–2015. Ecology and Evolution, 7(18), 7213-7230. https://doi.org/10.1002/ece3.3254

Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers (2017)
Journal Article
Packer, R. M. A., Volk, H. A., & Fowkes, R. C. (2017). Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers. Physiology and Behavior, 177, 27-33. https://doi.org/10.1016/j.physbeh.2017.04.008

There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to... Read More about Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers.

Mortality due to trauma in cats attending veterinary practices in central and south-east England (2017)
Journal Article
McDonald, J. L., Cleasby, I. R., Brodbelt, D. C., Church, D. B., & O'Neill, D. G. (2017). Mortality due to trauma in cats attending veterinary practices in central and south-east England. Journal of Small Animal Practice, 58(10), 570-576. https://doi.org/10.1111/jsap.12716

Objectives: To identify important demographic and spatial factors associated with the risk of trauma and, more specifically, road traffic accident‐related mortality, relative to other diagnoses in cats.

Methods: A sample of 2738 cats with mortalit... Read More about Mortality due to trauma in cats attending veterinary practices in central and south-east England.

Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis (2017)
Journal Article
Javaheri, B., Poulet, B., Aljazzar, A., De Souza, R., Piles, M., Hopkinson, M., Shervill, E., Pollard, A. S., Chan, B., Chang, Y. M., Orriss, I., Lee, P., & Pitsillides, A. A. (2017). Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis. BONE, 103, 308-317. https://doi.org/10.1016/j.bone.2017.07.028

Osteoarthritis (OA), affecting joints and bone, causes physical gait disability with huge socio-economic burden; treatment remains palliative. Roles for antioxidants in protecting against such chronic disorders have been examined previously. Sulforap... Read More about Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis.

A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale (2017)
Journal Article
Fournié, G., Høg, E., Barnett, T., Pfeiffer, D. U., & Mangtani, P. (2017). A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale. American Journal of Tropical Medicine and Hygiene, 97(2), 376-388. https://doi.org/10.4269/ajtmh.17-0014

Almost all human infections by avian influenza viruses (AIVs) are transmitted from poultry. A systematic review was conducted to identify practices associated with human infections, their prevalence, and rationale. Observational studies were identifi... Read More about A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale.

In search of morphological modules: a systematic review (2017)
Journal Article
Esteve-Altava, B. (2017). In search of morphological modules: a systematic review. Biological Reviews, 92(3), 1332-1347. https://doi.org/10.1111/brv.12284

Morphological modularity arises in complex living beings due to a semi-independent inheritance, development, and function of body parts. Modularity helps us to understand the evolvability and plasticity of organismal form, and how morphological varia... Read More about In search of morphological modules: a systematic review.

Clinical, histological and prognostic features of a novel nail-bed lesion of cats: 41 cases (2017)
Journal Article
Dobromylskyj, M. J., Fernandes, R. A., French, A., Pocknell, S. M., & Smith, K. C. (2017). Clinical, histological and prognostic features of a novel nail-bed lesion of cats: 41 cases. Journal of Feline Medicine and Surgery, 19(8), 853-859. https://doi.org/10.1177/1098612X16661013

There is a distinct subset of lesions arising on the digits of cats, located at or close to the nail-bed epithelium, which are typically composed of proliferative fibroblast-like cells, multinucleate giant cells and areas of osseous metaplasia, but c... Read More about Clinical, histological and prognostic features of a novel nail-bed lesion of cats: 41 cases.

Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers (2017)
Journal Article
Delabouglise, A., Antoine-Moussiaux, N., Tatong, D., Chumkaeo, A., Binot, A., Fournié, G., Pilot, E., Phimpraphi, W., Kasemsuwan, S., Paul, M. C., Duboz, R., Salem, G., & Peyre, M. (2017). Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers. Transboundary and Emerging Diseases, 64(4), 1294-1305. https://doi.org/10.1111/tbed.12506

Effectiveness of current passive zoonotic disease surveillance systems is limited by the under-reporting of disease outbreaks in the domestic animal population. Evaluating the acceptability of passive surveillance and its economic, social and cultura... Read More about Cultural Practices Shaping Zoonotic Diseases Surveillance: The Case of Highly Pathogenic Avian Influenza and Thailand Native Chicken Farmers.

An empirical analysis of the cost of rearing dairy heifers from birth to first calving and the time taken to repay these costs (2017)
Journal Article
Boulton, A. C., Rushton, J., & Wathes, D. C. (2017). An empirical analysis of the cost of rearing dairy heifers from birth to first calving and the time taken to repay these costs. animal, 11(8), 1372-1380. https://doi.org/10.1017/S1751731117000064

Rearing quality dairy heifers is essential to maintain herds by replacing culled cows. Information on the key factors influencing the cost of rearing under different management systems is, however, limited and many farmers are unaware of their true c... Read More about An empirical analysis of the cost of rearing dairy heifers from birth to first calving and the time taken to repay these costs.