Outputs (48)

Resequencing and signatures of selection scan in two Siberian native sheep breeds point to candidate genetic variants for adaptation and economically important traits (2020)
Journal Article
Sweet‐Jones, J., Yurchenko, A. A., Igoshin, A. V., Yudin, N. S., Swain, M. T., & Larkin, D. M. (2021). Resequencing and signatures of selection scan in two Siberian native sheep breeds point to candidate genetic variants for adaptation and economically important traits. Animal Genetics, https://doi.org/10.1111/age.13015

Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species (2019)
Journal Article
Proskuryakova, A. A., Kulemzina, A. I., Perelman, P. L., Yudkin, D. V., Lemskaya, N. A., Okhlopkov, I. M., Kirillin, E. V., Farré, M., Larkin, D. M., Roelke-Parker, M. E., O'Brien, S. J., Bush, M., & Graphodatsky, A. S. (2019). Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species. Genes, 10(11), 857. https://doi.org/10.3390/genes10110857

Bovidae, the largest family in Pecora infraorder, are characterized by a striking variability in diploid number of chromosomes between species and among individuals within a species. The bovid X chromosome is also remarkably variable, with several mo... Read More about Comparative Chromosome Mapping of Musk Ox and the X Chromosome among Some Bovidae Species.

Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes (2019)
Journal Article
Attardo, G. M., Abd-Alla, A. M. M., Acosta-Serrano, A., Allen, J. E., Bateta, R., Benoit, J. B., Bourtzis, K., Caers, J., Caljon, G., Christensen, M. B., Farrow, D. W., Friedrich, M., Hua-Van, A., Jennings, E. C., Larkin, D. M., Lawson, D., Lehane, M. J., Lenis, V. P., Lowy-Gallego, E., Macharia, R. W., …Aksoy, S. (2019). Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes. Genome Biology, 20, 187. https://doi.org/10.1186/s13059-019-1768-2

Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. Tsetse flies are distinguished from other Diptera by unique adaptations, including lactation and the birthing of live young (obligate vivip... Read More about Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes.

An integrated chromosome-scale genome assembly of the Masai Giraffe (Giraffa camelopardalis tippelskirchi) (2019)
Journal Article
Farré, M., Qiye, L., Daroli, I., Zhou, Y., Damas, J., Proskuryakova, A. A., Kulemzina, A. I., Chemnick, L. G., Kim, J., Ryder, O. A., Ma, J., Graphodatsky, A. S., Zhang, G., Larkin, D. M., & Lewin, H. A. (2019). An integrated chromosome-scale genome assembly of the Masai Giraffe (Giraffa camelopardalis tippelskirchi). GigaScience, 8(8), https://doi.org/10.1093/gigascience/giz090

High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia (2019)
Journal Article
Yurchenko, A. A., Deniskova, T. E., Yudin, N. S., Dotsev, A. V., Khamiruev, T. N., Selionova, M. I., Egorov, S. V., Reyer, H., Wimmers, K., Brem, G., Zinovieva, N. A., & Larkin, D. M. (2019). High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia. BMC Genomics, 20(Suppl 3), https://doi.org/10.1186/s12864-019-5537-0

Domestication and centuries of selective breeding have changed genomes of sheep breeds to respond to environmental challenges and human needs. The genomes of local breeds, therefore, are valuable sources of genomic variants to be used to understand m... Read More about High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia.

Germline-restricted chromosome (GRC) is widespread among songbirds (2019)
Journal Article
Torgasheva, A. A., Malinovskaya, L. P., Zadesenets, K. S., Karamysheva, T. V., Kizilova, E. A., Akberdina, E. A., Pristyazhnyuk, I. E., Shnaider, E. P., Volodkina, V. A., Saifitdinova, A. F., Galkina, S. A., Larkin, D. M., Rubtsov, N. B., & Borodin, P. M. (2019). Germline-restricted chromosome (GRC) is widespread among songbirds. https://doi.org/10.1073/pnas.1817373116

An unusual supernumerary chromosome has been reported for two related avian species, the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is eliminated from somatic cells and spermatids and transmitted via oocytes only. I... Read More about Germline-restricted chromosome (GRC) is widespread among songbirds.

Genome-wide association study for body weight in cattle populations from Siberia (2019)
Journal Article
Igoshin, A. V., Yudin, N. S., Belonogova, N. M., & Larkin, D. M. (2019). Genome-wide association study for body weight in cattle populations from Siberia. Animal Genetics, 50(3), 250-253. https://doi.org/10.1111/age.12786

Body weight is a complex trait in cattle associated with commonly used commercial breeding measurements related to growth. Although many quantitative trait loci (QTL) for body weight have been identified in cattle so far, searching for genetic determ... Read More about Genome-wide association study for body weight in cattle populations from Siberia.

Time lapse: A glimpse into prehistoric genomics (2019)
Journal Article
Griffin, D. K., Larkin, D. M., & O'Connor, R. E. (2019). Time lapse: A glimpse into prehistoric genomics. European Journal of Medical Genetics, https://doi.org/10.1016/j.ejmg.2019.03.004

For the purpose of this review, ‘time-lapse’ refers to the reconstruction of ancestral (in this case dinosaur) karyotypes using genome assemblies of extant species. Such reconstructions are only usually possible when genomes are assembled to ‘chromos... Read More about Time lapse: A glimpse into prehistoric genomics.

Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations (2019)
Journal Article
Igoshin, A. V., Yurchenko, A. A., Belonogova, N. M., Petrovsky, D. V., Aitnazarov, R. B., Soloshenko, V. A., Yudin, N. S., & Larkin, D. M. (2019). Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations. BMC Genomics, 20(Suppl 1), https://doi.org/10.1186/s12863-019-0725-0

Design of new highly productive livestock breeds, well-adapted to local climatic conditions is one of the aims of modern agriculture and breeding. The genetics underlying economically important traits in cattle are widely studied, whereas our knowled... Read More about Genome-wide association study and scan for signatures of selection point to candidate genes for body temperature maintenance under the cold stress in Siberian cattle populations.

Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks (2019)
Journal Article
Farre Belmonte, M., Kim, J., Proskuryakova, A. A., Zhang, Y., Kulemzina, A. I., Li, Q., Xiong, Y., Johnson, J. L., Perelman, P. L., Johnson, W. E., Warren, W., Kukekova, A. V., Zhang, G., O'Brien, S. J., Ryder, O. A., Graphodatsky, A. S., Ma, J., Lewin, H. A., & Larkin, D. M. (2019). Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks. Genome Research, 29, 576-589. https://doi.org/10.1101/gr.239863.118

The role of chromosome rearrangements in driving evolution has been a long-standing question of evolutionary biology. Here we focused on ruminants as a model to assess how rearrangements may have contributed to the evolution of gene regulation. Using... Read More about Evolution of gene regulation in ruminants differs between evolutionary breakpoint regions and homologous synteny blocks.