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Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli (2017)
Journal Article
Baker, K. R., Sigurðardóttir, H. H., Jana, B., & Guardabassi, L. (2017). Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli. Antimicrobial Agents and Chemotherapy, 61(3), e01773-16. https://doi.org/10.1128/AAC.01773-16

Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing... Read More about Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli.

A Blueprint to Evaluate One Health (2017)
Journal Article
Rüegg, S., McMahon, B. J., Haesler, B., Esposito, R., Nielsen, L. R., Ifejika Speranza, C., Ehlinger, T., Peyre, M., Aragrande, M., Zinsstag, J., Davies, P., Mihalca, A. D., Buttigieg, S. C., Rushton, J., Carmo, L. P., De Meneghi, D., Canali, M., Filippitzi, M. E., Goutard, F. L., Ilieski, V., …Lindberg, A. (2017). A Blueprint to Evaluate One Health. Frontiers in Public Health, 5, https://doi.org/10.3389/fpubh.2017.00020

The secondary resistome of multidrug-resistant Klebsiella pneumoniae (2017)
Journal Article
Jana, B., Cain, A. K., Doerrler, W. T., Boinett, C. J., Fookes, M. C., Parkhill, J., & Guardabassi, L. (2017). The secondary resistome of multidrug-resistant Klebsiella pneumoniae. https://doi.org/10.1038/srep42483

Klebsiella pneumoniae causes severe lung and bloodstream infections that are difficult to treat due to multidrug resistance. We hypothesized that antimicrobial resistance can be reversed by targeting chromosomal non-essential genes that are not respo... Read More about The secondary resistome of multidrug-resistant Klebsiella pneumoniae.

Early animal farming and zoonotic disease dynamics: modelling brucellosis transmission in Neolithic goat populations (2017)
Journal Article
Fournié, G., Pfeiffer, D. U., & Bendrey, R. (2017). Early animal farming and zoonotic disease dynamics: modelling brucellosis transmission in Neolithic goat populations. Royal Society Open Science, 4, 160943. https://doi.org/10.1098/rsos.160943

Zoonotic pathogens are frequently hypothesized as emerging with the origins of farming, but evidence of this is elusive in the archaeological records. To explore the potential impact of animal domestication on zoonotic disease dynamics and human infe... Read More about Early animal farming and zoonotic disease dynamics: modelling brucellosis transmission in Neolithic goat populations.