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Outputs (214)

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity (2017)
Journal Article
Doyle, S. R., Bourguinat, C., Nana-Djeunga, H. C., Kengne-Ouafo, J. A., Pion, S. D. S., Bopda, J., …Grant, W. N. (2017). Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity. PLoS Neglected Tropical Diseases, 11, e0005816. https://doi.org/10.1371/journal.pntd.0005816

Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta) (2017)
Journal Article
Suárez-Bonnet, A., Grau-Bassas, E. R., Herráez, P., Quesada-Canales, O., Priestnall, S. L., & De Los Monteros, A. E. (2017). Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta). Journal of Comparative Pathology, 157(2-3), 85-89. https://doi.org/10.1016/j.jcpa.2017.06.009

Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands. Surgical removal revealed that both masses were comprised of multiple nodules... Read More about Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta).

Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella (2017)
Journal Article
Kundu, K., Garg, R., Kumar, S., Mandal, M., Tomley, F. M., Blake, D. P., & Banerjee, P. S. (2017). Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella. Veterinary Parasitology, 244, 44-53. https://doi.org/10.1016/j.vetpar.2017.07.025

Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine cand... Read More about Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella.

Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach (2017)
Journal Article
Métras, R., Fournié, G., Dommergues, L., Camacho, A., Cavalerie, L., Mérot, P., …Edmunds, W. J. (2017). Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach. PLoS Neglected Tropical Diseases, 11(7), e0005767. https://doi.org/10.1371/journal.pntd.0005767

Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the mos... Read More about Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach.

Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (2017)
Journal Article
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration. https://doi.org/10.1038/cddis.2017.332

Tamoxifen (TAM) has recently been shown to cause acute gastric atrophy and metaplasia in mice. We have previously demonstrated that the outcome of Helicobacter felis infection, which induces similar gastric lesions in mice, is altered by deletion of... Read More about Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness (2017)
Journal Article
Walker, M., Pion, S. D. S., Fang, H., Gardon, J., Kamgno, J., Basáñez, M., & Boussinesq, M. (2017). The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness. Clinical Infectious Diseases, 65(12), 2026-2034. https://doi.org/10.1093/cid/cix616

Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca vol... Read More about The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness.

Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam (2017)
Journal Article
Delabouglise, A., Choisy, M., Phan, T. D., Antoine-Moussiaux, N., Peyre, M., Vu, T. D., …Fournié, G. (2017). Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam. Scientific Reports, 7, 5905. https://doi.org/10.1038/s41598-017-06244-6

While climate is often presented as a key factor influencing the seasonality of diseases, the importance of anthropogenic factors is less commonly evaluated. Using a combination of methods-wavelet analysis, economic analysis, statistical and disease... Read More about Economic factors influencing zoonotic disease dynamics: demand for poultry meat and seasonal transmission of avian influenza in Vietnam.

Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda (2017)
Journal Article
Nolan, M. J., Unger, M., Yeap, Y. T., Rogers, E., Millet, I., Harman, K., …Blake, D. P. (2017). Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda. https://doi.org/10.1186/s13071-017-2283-5

Over 60 % of human emerging infectious diseases are zoonotic, and there is growing evidence of the zooanthroponotic transmission of diseases from humans to livestock and wildlife species, with major implications for public health, economics, and cons... Read More about Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda.

Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation (2017)
Journal Article
Burn, C. C. (2017). Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation. Animal Behaviour, 130, 141-151. https://doi.org/10.1016/j.anbehav.2017.06.006

Boredom is likely to have adaptive value in motivating exploration and learning, and many animals may possess the basic neurological mechanisms to support it. Chronic inescapable boredom can be extremely aversive, and understimulation can harm neural... Read More about Bestial boredom: a biological perspective on animal boredom and suggestions for its scientific investigation.

The effects of intrauterine infusion of peanut oil on endometrial health, salivary cortisol and interovulatory period in mares (2017)
Journal Article
Campbell, M. L. H., Hampshire, D., Hamstead, L., Rose, B., Smith, K. C., & De Mestre, A. M. (2017). The effects of intrauterine infusion of peanut oil on endometrial health, salivary cortisol and interovulatory period in mares. Theriogenology, 102, 116-125. https://doi.org/10.1016/j.theriogenology.2017.07.009

Intrauterine infusion of peanut oil at Day 10 post-ovulation has been reported to prolong dioestrus in mares. However, the effects of peanut oil treatment on the endometrium and whether the technique is painful have not been assessed. The objectives... Read More about The effects of intrauterine infusion of peanut oil on endometrial health, salivary cortisol and interovulatory period in mares.