L Osagie-Clouard
The influence of parathyroid hormone 1-34 on the osteogenic characteristics of adipose- and bone-marrow-derived mesenchymal stem cells from juvenile and ovarectomized rats
Osagie-Clouard, L; Sanghani-Kerai, A; Coathup, M; Meeson, R; Briggs, T; Blunn, G
Authors
A Sanghani-Kerai
M Coathup
R Meeson
T Briggs
G Blunn
Abstract
Mesenchymal stem cells (MSCs) are of growing interest in terms of bone regeneration. Most preclinical trials utilize bone-marrow-derived mesenchymal stem cells (bMSCs), although this is not without isolation and expansion difficulties. The aim of this study was: to compare the characteristics of bMSCs and adipose-derived mesenchymal stem cells (AdMSCs) from juvenile, adult, and ovarectomized (OVX) rats; and to assess the effect of human parathyroid hormone (hPTH) 1-34 on their osteogenic potential and migration to stromal cell-derived factor-1 (SDF-1).
Citation
Osagie-Clouard, L., Sanghani-Kerai, A., Coathup, M., Meeson, R., Briggs, T., & Blunn, G. (2019). The influence of parathyroid hormone 1-34 on the osteogenic characteristics of adipose- and bone-marrow-derived mesenchymal stem cells from juvenile and ovarectomized rats. https://doi.org/10.1302/2046-3758.88.BJR-2019-0018.R1
Journal Article Type | Article |
---|---|
Acceptance Date | Aug 2, 2019 |
Publication Date | Aug 23, 2019 |
Deposit Date | Mar 4, 2020 |
Publicly Available Date | Mar 4, 2020 |
Journal | Bone and Joint Research |
Peer Reviewed | Peer Reviewed |
Volume | 8 |
Issue | 8 |
Pages | 397-404 |
DOI | https://doi.org/10.1302/2046-3758.88.BJR-2019-0018.R1 |
Public URL | https://rvc-repository.worktribe.com/output/1380785 |
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