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A Cryptosporidium parvum genotype shift between week old and two week old calves following administration of a prophylactic antiprotozoal

Seale, J; Swain, J; Booth, R E; Blake, D P

Authors

J Seale

J Swain

R E Booth

D P Blake



Abstract

This study looked to assess the stability of Cryptosporidium parvum genotypes in calves between the final day of treatment with the antiprotozoal halofuginone lactate and seven days post-treatment. Paired faecal samples were collected on the final day of treatment and seven days later from 54 calves across seven farms in South-west England. The presence of Cryptosporidium species was detected using polymerase chain reaction targeting the 18 s rDNA. The presence and genotype of C. parvum was determined by PCR and amplicon sequencing targeting the gp60 locus. On farms where C. parvum was detected at both sampling times there was a distinct genotype shift. Detection of gp60 genotype IIaA15G2R1 decreased from 40% to 7% while IIaA17G1R1 increased from 0% to 41%, supplemented by IIaA16G3R1 in one sample. A shift in C. parvum genotypes present in calves within a one week sampling timeframe has not been described prior to this study, indicating that the timeframe is likely suitable for observing variation in C. parvum populations and interactions with antiprotozoal control strategies.

Citation

Seale, J., Swain, J., Booth, R. E., & Blake, D. P. (2019). A Cryptosporidium parvum genotype shift between week old and two week old calves following administration of a prophylactic antiprotozoal. Veterinary Parasitology, 273, 32-35. https://doi.org/10.1016/j.vetpar.2019.07.009

Journal Article Type Other
Acceptance Date Jul 26, 2019
Publication Date Jul 27, 2019
Deposit Date Jul 31, 2019
Publicly Available Date Mar 28, 2024
Journal VETERINARY PARASITOLOGY
Print ISSN 0304-4017
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 273
Pages 32-35
DOI https://doi.org/10.1016/j.vetpar.2019.07.009
Public URL https://rvc-repository.worktribe.com/output/1381081

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