R Verma
A novel, high-sensitivity, bacteriophage-based assay identifies low level Mycobacterium tuberculosis bacteraemia in immunocompetent patients with active and incipient tuberculosis
Verma, R; Swift, B M C; Handley-Hartill, W; Lee, J K; Woltmann, G; Rees, C E D; Haldar, P
Authors
B M C Swift
W Handley-Hartill
J K Lee
G Woltmann
C E D Rees
P Haldar
Abstract
Haematogenous dissemination of M. tuberculosis (Mtb) is critical to pathogenesis of progressive tuberculous infection in animal models. Using a novel phage-based blood assay, we report the first concordant evidence in well-characterised immunocompetent human cohorts, demonstrating associations of Mtb bacteraemia with progressive phenotypes of latent infection and active pulmonary TB respectively.
Citation
Verma, R., Swift, B. M. C., Handley-Hartill, W., Lee, J. K., Woltmann, G., Rees, C. E. D., & Haldar, P. (2019). A novel, high-sensitivity, bacteriophage-based assay identifies low level Mycobacterium tuberculosis bacteraemia in immunocompetent patients with active and incipient tuberculosis. Clinical Infectious Diseases, 70(5), 933-936. https://doi.org/10.1093/cid/ciz548
Journal Article Type | Article |
---|---|
Acceptance Date | Jun 11, 2019 |
Publication Date | Jun 22, 2019 |
Deposit Date | Jul 5, 2019 |
Publicly Available Date | Jun 23, 2020 |
Journal | CLINICAL INFECTIOUS DISEASES |
Print ISSN | 1058-4838 |
Publisher | Oxford University Press |
Peer Reviewed | Peer Reviewed |
Volume | 70 |
Issue | 5 |
Pages | 933-936 |
DOI | https://doi.org/10.1093/cid/ciz548 |
Public URL | https://rvc-repository.worktribe.com/output/1381610 |
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