H E Wong
Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig
Wong, H E; Hedley, J; Stapleton, N; Murphy, B; Priestnall, S L
Authors
J Hedley
N Stapleton
B Murphy
S L Priestnall
Abstract
Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ameloblastic fibro-odontomas. The presence or absence of intralesional, induced non-neoplastic tissue must be accounted for in the diagnosis. Herein we describe a naturally occurring odontoameloblastoma with extensive chondroid cementum deposition in a guinea pig (Cavia porcellus). Microscopically, the mass featured palisading neoplastic odontogenic epithelium closely apposed to ribbons and rings of a pink dental matrix (dentinoid), alongside extensive sheets and aggregates of chondroid cementum. The final diagnosis was an odontoameloblastoma given the abundance of odontogenic epithelium in association with dentinoid but a paucity of pulp ectomesenchyme. Chondroid cementum is an expected anatomical feature of cavies, and its presence within the odontoameloblastoma was interpreted as a response of the ectomesenchyme of the dental follicle to the described neoplasm. Our case illustrates the inductive capabilities of odontoameloblastomas while highlighting species-specific anatomy that has resulted in a histologic appearance unique to cavies and provides imaging and histologic data to aid diagnosis of these challenging lesions.
Citation
Wong, H. E., Hedley, J., Stapleton, N., Murphy, B., & Priestnall, S. L. (2018). Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718794784
Journal Article Type | Article |
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Acceptance Date | Aug 1, 2018 |
Publication Date | Aug 22, 2018 |
Deposit Date | Aug 25, 2018 |
Publicly Available Date | Nov 21, 2020 |
Journal | JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION |
Print ISSN | 1040-6387 |
Publisher | SAGE Publications |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1177/1040638718794784 |
Public URL | https://rvc-repository.worktribe.com/output/1386194 |
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