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Computer simulation of syringomyelia in dogs

Cirovic, S; Lloyd, R E; Jovanovik, J; Volk, H A; Rusbridge, C


S Cirovic

R E Lloyd

J Jovanovik

H A Volk

C Rusbridge


Syringomyelia is a pathological condition in which fluid-filled cavities (syringes) form and expand in the spinal cord. Syringomyelia is often linked with obstruction of the craniocervical junction and a Chiari malformation, which is similar in both humans and animals. Some brachycephalic toy breed dogs such as Cavalier King Charles Spaniels (CKCS) are particularly predisposed. The exact mechanism of the formation of syringomyelia is undetermined and consequently with the lack of clinical explanation, engineers and mathematicians have resorted to computer models to identify possible physical mechanisms that can lead to syringes. We developed a computer model of the spinal cavity of a CKCS suffering from a large syrinx. The model was excited at the cranial end to simulate the movement of the cerebrospinal fluid (CSF) and the spinal cord due to the shift of blood volume in the cranium related to the cardiac cycle. To simulate the normal condition, the movement was prescribed to the CSF. To simulate the pathological condition, the movement of CSF was blocked.


Cirovic, S., Lloyd, R. E., Jovanovik, J., Volk, H. A., & Rusbridge, C. (in press). Computer simulation of syringomyelia in dogs. BMC Veterinary Research, 14, 82.

Journal Article Type Article
Acceptance Date Mar 2, 2018
Deposit Date Apr 6, 2018
Publicly Available Date Apr 6, 2018
Journal BMC Veterinary Research
Publisher BioMed Central
Peer Reviewed Peer Reviewed
Volume 14
Pages 82
Public URL


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