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Transient Myocardial Thickening in Cats Associated with Heart Failure

Novo Matos, J; Pereira, N; Glaus, T; Wilkie, L; Borgeat, K A; Loureiro, J; Silva, J; Law, V; Kranjc, A; Connolly, D J; Fuentes, V L


J Novo Matos

N Pereira

T Glaus

L Wilkie

K A Borgeat

J Loureiro

J Silva

V Law

A Kranjc

D J Connolly

V L Fuentes


Background: Cats with hypertrophic cardiomyopathy (HCM) and congestive heart failure (CHF) can have resolution of both left ventricular hypertrophy and CHF.

Objectives: To describe the clinical characteristics of cats with transient myocardial thickening (TMT) and CHF compared with a control population of cats without resolution of HCM.

Animals: A total of 21 cats with TMT, 21 cats with HCM.

Methods: Retrospective study. Clinical records at 4 veterinary centers were searched for TMT cases and a control group of cats with HCM and CHF. TMT was defined as initial maximal left ventricular wall thickness (LVWT) >= 6 mm with left-sided CHF, with subsequent resolution of CHF, reduction in left atrium/aorta (LA/Ao), and LVWT= 6 mm.

Results: Cats with TMT were younger (2 [0.4-11.4] years) than cats with HCM (8 [1.6-14] years) (P < 0.0001), and antecedent events were more common (15/21 versus 6/21, respectively) (P = 0.01). In cats with TMT, LVWT normalized from 6.8 [6.0-9.7] mm to 4.8 [2.8-5.3] mm and LA/Ao decreased from 1.8 [1.6-2.3] to 1.45 [1.2-1.7] after a mean interval of 3.3 (95% CI: 1.8-4.7) months. CHF recurred in 1 of 21 TMT and 15 of 21 cats with HCM. Cardiac treatment was discontinued in 20 of 21 cats with TMT and 0 of 21 HCM cats. All cats with TMT survived, whereas 8 of 19 cats with HCM died during the study period.

Conclusions and Clinical Importance: TMT occurs in younger cats, and antecedent events are common. The prognosis is better in cats with CHF associated with TMT than HCM.


Novo Matos, J., Pereira, N., Glaus, T., Wilkie, L., Borgeat, K. A., Loureiro, J., …Fuentes, V. L. (2017). Transient Myocardial Thickening in Cats Associated with Heart Failure. Journal of Veterinary Internal Medicine, 32(1), 48-56.

Journal Article Type Article
Acceptance Date Nov 7, 2017
Publication Date Dec 15, 2017
Deposit Date Jan 19, 2018
Publicly Available Date Jan 19, 2018
Print ISSN 0891-6640
Publisher Wiley Open Access
Peer Reviewed Peer Reviewed
Volume 32
Issue 1
Pages 48-56
Public URL


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