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Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies

Florey, J; Viall, A; Streu, S; DiMuro, V; Riddle, A L; Kirk, J; Perazzotti, L; Affeldt, K; Wagner, R; Vaden, S L; Harris, T; Allenspach, K

Authors

J Florey

A Viall

S Streu

V DiMuro

A L Riddle

J Kirk

L Perazzotti

K Affeldt

R Wagner

S L Vaden

T Harris

K Allenspach



Abstract

Perinuclear antineutrophil cytoplasmic antibodies (pANCA) previously have been shown to be serum markers in dogs with chronic enteropathies, with dogs that have food‐responsive disease (FRD) having higher frequencies of seropositivity than dogs with steroid‐responsive disease (SRD). The indirect immunofluorescence (IIF) assay used in previous publications is time‐consuming to perform, with low interobserver agreement. Forty‐four dogs with FRD, 20 dogs with SRD, 20 control dogs, and 38 soft‐coated wheaten terrier (SCWT) or SCWT‐cross dogs.

Citation

Florey, J., Viall, A., Streu, S., DiMuro, V., Riddle, A. L., Kirk, J., …Allenspach, K. (2017). Use of a Granulocyte Immunofluorescence Assay Designed for Humans for Detection of Antineutrophil Cytoplasmic Antibodies in Dogs with Chronic Enteropathies. Journal of Veterinary Internal Medicine, 31(4), 1062-1066. https://doi.org/10.1111/jvim.14774

Journal Article Type Article
Acceptance Date May 6, 2017
Publication Date Jun 13, 2017
Deposit Date Sep 2, 2017
Publicly Available Date Mar 28, 2024
Journal JOURNAL OF VETERINARY INTERNAL MEDICINE
Print ISSN 0891-6640
Publisher Wiley Open Access
Peer Reviewed Peer Reviewed
Volume 31
Issue 4
Pages 1062-1066
DOI https://doi.org/10.1111/jvim.14774
Public URL https://rvc-repository.worktribe.com/output/1391527