J Cheetham
Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model
Cheetham, J; Perkins, J D M; Jarvis, J C; Cercone, M; Maw, M; Hermanson, J W; Mitchell, L M; Piercy, R J; Ducharme, N G
Authors
J D M Perkins
J C Jarvis
M Cercone
M Maw
J W Hermanson
L M Mitchell
R J Piercy
N G Ducharme
Abstract
Bilateral vocal fold paralysis (BVCP) is a life?threatening condition that follows injury to the Recurrent Laryngeal nerve (RLn) and denervation of the intrinsic laryngeal musculature. Functional electrical stimulation (FES) enables restoration and control of a wide variety of motor functions impaired by lower motor neuron lesions. Here we evaluate the effects of FES on the sole arytenoid abductor, the posterior cricoarytenoid (PCA) muscle in a large animal model of RLn injury. Ten horses were instrumented with two quadripolar intramuscular electrodes in the left PCA muscle. Following a 12?week denervation period, the PCA was stimulated using a once?daily training session for 8 weeks in seven animals. Three animals were used as unstimulated controls. Denervation produced a significant increase in rheobase (P?
Citation
Cheetham, J., Perkins, J. D. M., Jarvis, J. C., Cercone, M., Maw, M., Hermanson, J. W., …Ducharme, N. G. (2015). Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model. Artificial Organs, 39(10), 876-885. https://doi.org/10.1111/aor.12624
Journal Article Type | Article |
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Acceptance Date | Oct 15, 2015 |
Publication Date | Oct 16, 2015 |
Deposit Date | Dec 17, 2015 |
Publicly Available Date | Nov 21, 2020 |
Journal | Artificial Organs |
Print ISSN | 0160-564X |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 39 |
Issue | 10 |
Pages | 876-885 |
DOI | https://doi.org/10.1111/aor.12624 |
Public URL | https://rvc-repository.worktribe.com/output/1399413 |