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Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model

Cheetham, J; Perkins, J D M; Jarvis, J C; Cercone, M; Maw, M; Hermanson, J W; Mitchell, L M; Piercy, R J; Ducharme, N G

Authors

J Cheetham

J D M Perkins

J C Jarvis

M Cercone

M Maw

J W Hermanson

L M Mitchell

R J Piercy

N G Ducharme



Abstract

Bilateral vocal fold paralysis (BVCP) is a life‐threatening condition that follows injury to the Recurrent Laryngeal nerve (RLn) and denervation of the intrinsic laryngeal musculature. Functional electrical stimulation (FES) enables restoration and control of a wide variety of motor functions impaired by lower motor neuron lesions. Here we evaluate the effects of FES on the sole arytenoid abductor, the posterior cricoarytenoid (PCA) muscle in a large animal model of RLn injury. Ten horses were instrumented with two quadripolar intramuscular electrodes in the left PCA muscle. Following a 12‐week denervation period, the PCA was stimulated using a once‐daily training session for 8 weeks in seven animals. Three animals were used as unstimulated controls. Denervation produced a significant increase in rheobase (P 

Citation

Cheetham, J., Perkins, J. D. M., Jarvis, J. C., Cercone, M., Maw, M., Hermanson, J. W., …Ducharme, N. G. (2015). Effects of Functional Electrical Stimulation on Denervated Laryngeal Muscle in a Large Animal Model. Artificial Organs, 39(10), 876-885. https://doi.org/10.1111/aor.12624

Journal Article Type Article
Acceptance Date Oct 15, 2015
Publication Date Oct 16, 2015
Deposit Date Dec 17, 2015
Publicly Available Date Mar 28, 2024
Journal Artificial Organs
Print ISSN 0160-564X
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 39
Issue 10
Pages 876-885
DOI https://doi.org/10.1111/aor.12624
Public URL https://rvc-repository.worktribe.com/output/1399413

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