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Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK

Beever, L J; Bond, R; Graham, P A; Jackson, B F; Lloyd, D H; Loeffler, A

Authors

L J Beever

R Bond

P A Graham

B F Jackson

D H Lloyd

A Loeffler



Abstract

Frequencies of antimicrobial resistance were determined amongst 14,555 clinical Staphylococcus intermedius group (SIG) isolates from UK dogs and cats to estimate resistance trends and quantify the occurrence of meticillin-resistant Staphylococcus pseudintermedius (MRSP). Reports from two diagnostic laboratories (13,313 general submissions, 1242 referral centre only submissions) were analysed retrospectively (2003/2006–2012). MRSP were defined by phenotypic resistance to meticillin and concurrent broad β-lactam resistance; a subset was confirmed genetically (SIG-specific nuc and mecA). Trends were analysed by Cochran-Armitage test. Resistance remained below 10 per cent for cefalexin, amoxicillin-clavulanic acid and the fluoroquinolones. Increasing resistance trends were seen in both laboratories for ampicillin/amoxicillin (both P

Citation

Beever, L. J., Bond, R., Graham, P. A., Jackson, B. F., Lloyd, D. H., & Loeffler, A. (2014). Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK. Veterinary Record, 176(7), 172+. https://doi.org/10.1136/vr.102651

Journal Article Type Article
Acceptance Date Oct 12, 2014
Publication Date Nov 14, 2014
Deposit Date Nov 11, 2014
Publicly Available Date Mar 29, 2024
Journal VETERINARY RECORD
Print ISSN 0042-4900
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 176
Issue 7
Pages 172+
DOI https://doi.org/10.1136/vr.102651
Public URL https://rvc-repository.worktribe.com/output/1404694
Additional Information Corporate Creators : NationWide Labs