Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK

Beever, L J; Bond, R; Graham, P A; Jackson, B F; Lloyd, D H; Loeffler, A

Abstract

Frequencies of antimicrobial resistance were determined amongst 14,555 clinical Staphylococcus intermedius group (SIG) isolates from UK dogs and cats to estimate resistance trends and quantify the occurrence of meticillin-resistant Staphylococcus pseudintermedius (MRSP). Reports from two diagnostic laboratories (13,313 general submissions, 1242 referral centre only submissions) were analysed retrospectively (2003/2006–2012). MRSP were defined by phenotypic resistance to meticillin and concurrent broad β-lactam resistance; a subset was confirmed genetically (SIG-specific nuc and mecA). Trends were analysed by Cochran-Armitage test. Resistance remained below 10 per cent for cefalexin, amoxicillin-clavulanic acid and the fluoroquinolones. Increasing resistance trends were seen in both laboratories for ampicillin/amoxicillin (both P

Citation

Beever, L. J., Bond, R., Graham, P. A., Jackson, B. F., Lloyd, D. H., & Loeffler, A. (2014). Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK. Veterinary Record, 176(7), 172+. https://doi.org/10.1136/vr.102651

• Journal Article Type: Article
• Acceptance Date: Oct 12, 2014
• Publication Date: Nov 14, 2014
• Deposit Date: Nov 11, 2014
• Journal: VETERINARY RECORD
• Print ISSN: 0042-4900
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 176
• Issue: 7
• Pages: 172+
• DOI: https://doi.org/10.1136/vr.102651
• Public URL: https://rvc-repository.worktribe.com/output/1404694
• Additional Information: Corporate Creators : NationWide Labs