Recommended Guidelines for Submission, Trimming, Margin Evaluation, and Reporting of Tumor Biopsy Specimens in Veterinary Surgical Pathology

Kamstock, D A; Ehrhart, E J; Getzy, D M; Bacon, N J; Rassnick, K M; Moroff, S D; Liu, S M; Straw, R C; McKnight, C A; Amorim, R L; Bienzle, D; Cassali, G D; Cullen, J M; Dennis, M M; Esplin, D G; Foster, R A; Goldschmidt, M H; Gruber, A D; Hellmen, E; Howerth, E W; Labelle, P; Lenz, S D; Lipscomb, T P; Locke, E; McGill, L D; Miller, M A; Mouser, P J; O'Toole, D; Pool, R R; Powers, B E; Ramos-Vara, J A; Roccabianca, P; Ross, A D; Sailasuta, A; Sarli, G; Scase, T J; Schulman, F Y; Shoieb, A M; Singh, K; Sledge, D; Smedley, R C; Smith, K C; Spangler, W L; Steficek, B; Stromberg, P C; Valli, V E; Yager, J; Kiupel, M

Abstract

eoplastic diseases are typically diagnosed by biopsy and histopathological evaluation. The pathology report is key in determining prognosis, therapeutic decisions, and overall case management and therefore requires diagnostic accuracy, completeness, and clarity. Successful management relies on collaboration between clinical veterinarians, oncologists, and pathologists. To date there has been no standardized approach or guideline for the submission, trimming, margin evaluation, or reporting of neoplastic biopsy specimens in veterinary medicine. To address this issue, a committee consisting of veterinary pathologists and oncologists was established under the auspices of the American College of Veterinary Pathologists Oncology Committee. These consensus guidelines were subsequently reviewed and endorsed by a large international group of veterinary pathologists. These recommended guidelines are not mandated but rather exist to help clinicians and veterinary pathologists optimally handle neoplastic biopsy samples. Many of these guidelines represent the collective experience of the committee members and consensus group when assessing neoplastic lesions from veterinary patients but have not met the rigors of definitive scientific study and investigation. These questions of technique, analysis, and evaluation should be put through formal scrutiny in rigorous clinical studies in the near future so that more definitive guidelines can be derived.

Citation

Kamstock, D. A., Ehrhart, E. J., Getzy, D. M., Bacon, N. J., Rassnick, K. M., Moroff, S. D., Liu, S. M., Straw, R. C., McKnight, C. A., Amorim, R. L., Bienzle, D., Cassali, G. D., Cullen, J. M., Dennis, M. M., Esplin, D. G., Foster, R. A., Goldschmidt, M. H., Gruber, A. D., Hellmen, E., Howerth, E. W., …Kiupel, M. Recommended Guidelines for Submission, Trimming, Margin Evaluation, and Reporting of Tumor Biopsy Specimens in Veterinary Surgical Pathology. Veterinary Pathology, 48(1), 19-31. https://doi.org/10.1177/0300985810389316

• Journal Article Type: Article
• Deposit Date: Nov 12, 2014
• Journal: VETERINARY PATHOLOGY
• Print ISSN: 0300-9858
• Electronic ISSN: 1544-2217
• Publisher: American College of Veterinary Pathologists
• Peer Reviewed: Peer Reviewed
• Volume: 48
• Issue: 1
• Pages: 19-31
• DOI: https://doi.org/10.1177/0300985810389316
• Public URL: https://rvc-repository.worktribe.com/output/1418767
• Additional Information: Corporate Creators : Anatomic Pathology Consultant, Angell Animal Medical Center, Boston, Antech Diagnostics, Armed Forces Institute of Pathology, ARUP Labs, Salt Lake City, Bologna, Bridge Pathology Ltd, Brisbane Vet Specialist Centre, Chulalongkorn, Coll of Vet Med, Cornell University, Colorado State University, Florida, Frankston Hospital, Freie Universitat, Berlin, Georgia, Guelph, Canada, Guelph, Canada, IDEXX Labs, Illinois, USA, Lab De Patologia Comparada, Brazil, Metropolitan Vet Path, New York, Michigan State University, Milan, Necropsy Service Group, North Carolina State University, Ohio State University, Pennsylvania School of Veterinary Medicine, Pfizer, Purdue University, Sao Paulo State, Swedish University of Agricultural Sciences, Sydney, Texas A&M, VDx Veterinary Diagnostics, Wyoming