Theileria Apicoplast as a Target for Chemotherapy

Lizundia, R; Werling, D; Langsley, G; Ralph, S A

Abstract

Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets. Putative inhibitors of these targets were screened, and we identified antiproliferative compounds that merit further characterization.

Citation

Lizundia, R., Werling, D., Langsley, G., & Ralph, S. A. Theileria Apicoplast as a Target for Chemotherapy. Antimicrobial Agents and Chemotherapy, 53(3), 1213-1217. https://doi.org/10.1128/aac.00126-08

• Journal Article Type: Article
• Deposit Date: Nov 11, 2014
• Journal: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
• Print ISSN: 0066-4804
• Publisher: American Society for Microbiology
• Volume: 53
• Issue: 3
• Pages: 1213-1217
• DOI: https://doi.org/10.1128/aac.00126-08
• Public URL: https://rvc-repository.worktribe.com/output/1426448
• Additional Information: Corporate Creators : Institut Cochin, France, Melbourne