All Outputs (201)

The Mechanics of Skeletal Development
Book Chapter
Novicky, A., Caetano-Silva, S. P., Javaheri, B., & Pitsillides, A. A. The Mechanics of Skeletal Development. . https://doi.org/10.1016/B978-0-12-811467-4.00002-4

Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo
Journal Article
Javaheri, B., Hopkinson, M., Poulet, B., Pollard, A. S., Shefelbine, S. J., Chang, Y. M., Francis-West, P., Bou-Gharios, G., & Pitsillides, A. A. (in press). Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo. PLoS ONE, 11(8), e0159657. https://doi.org/10.1371/journal.pone.0159657

The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice
Journal Article
Gohin, S., Carriero, A., Chenu, C., Pitsillides, A. A., Arnett, T. R., & Marenzana, M. (in press). The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice. Cell Biochemistry and Function, 34(2), 52-62. https://doi.org/10.1002/cbf.3164

SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS
Journal Article
Brenneis, C., Westhof, A., Duschek, J., Chang, Y. M., Pitsillides, A. A., Michaelis, M., Kleinschmidt, K., & Guehring, H. SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS

PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS
Journal Article
Chang, Y. M., Marsh-Dougerthy, J., Brenneis, C., Kleinschmidt, K., Michaelis, M., Guehring, H., Piles, M., & Pitsillides, A. A. PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS

CHONDROCYTE-SPECIFIC TIMP3 OVEREXPRESSION DISRUPTS ENDOCHONDRAL GROWTH AND COMPROMISES BONE STRUCTURE AND INTEGRITY: FUNCTIONAL IMPACT OF THE CHONDROCYTE-TO-OSTEOBLAST LINEAGE
Presentation / Conference Contribution
Poulet, B., Liu, K., Plumb, D., Vo, P., Shah, M., Staines, K. A., Sampson, A., Nakamura, H., Nagase, H., Shefelbine, S., Pitsillides, A. A., Bou-Gharios, G., & Carrierro, A. CHONDROCYTE-SPECIFIC TIMP3 OVEREXPRESSION DISRUPTS ENDOCHONDRAL GROWTH AND COMPROMISES BONE STRUCTURE AND INTEGRITY: FUNCTIONAL IMPACT OF THE CHONDROCYTE-TO-OSTEOBLAST LINEAGE

Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis
Journal Article
Christiansen, B. A., Guilak, F., Lockwood, K. A., Olson, S. A., Pitsillides, A. A., Sandell, L. J., Silva, M. J., Van Der Meulen, M. C. H., & Haudenschild, D. R. (in press). Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis. Osteoarthritis and Cartilage, 23(10), 1627-1638. https://doi.org/10.1016/j.joca.2015.05.009

MMP and TIMP temporal gene expression during osteocytogenesis
Journal Article
Prideaux, M., Staines, K. A., Jones, E. R., Riley, G. P., Pitsillides, A. A., & Farquharson, C. (in press). MMP and TIMP temporal gene expression during osteocytogenesis. Gene Expression Patterns, 18(1-2), 29-36. https://doi.org/10.1016/j.gep.2015.04.004

Osteocytes within bone differentiate from osteoblast precursors which reside in a mineralised extracellular matrix (ECM). Fully differentiated osteocytes are critical for bone development and function but the factors that regulate this differentiatio... Read More about MMP and TIMP temporal gene expression during osteocytogenesis.

A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Presentation / Conference Contribution
Akbareian, S. E., Fowkes, R. C., Macharia, R., Pitsillides, A. A., & McGonnell, I. M. A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO

TRABECULAR ADAPTIVE RESPONSE TO LOADING IN AGED MICE IS RESTORED BY PRE-EXPOSURE TO SUPRAPHYSIOLOGICAL LOADS
Presentation / Conference Contribution
Javaheri, B., Wood, M. J., Carriero, A., Shefelbine, S., & Pitsillides, A. A. TRABECULAR ADAPTIVE RESPONSE TO LOADING IN AGED MICE IS RESTORED BY PRE-EXPOSURE TO SUPRAPHYSIOLOGICAL LOADS

GENDER DIFFERENCES OA PROGRESSION AND THEIR LONGITUDINAL GAIT CHANGES
Journal Article
Piles, M., De Souza, R., Poulet, B., Pitsillides, A. A., & Chang, Y. M. GENDER DIFFERENCES OA PROGRESSION AND THEIR LONGITUDINAL GAIT CHANGES

IDENTIFYING MECHANISMS AND EVOLUTIONARY IMPLICATIONS OF MECHANOSENSITIVE GROWTH IN THE EMBRYONIC LIMB SKELETON
Presentation / Conference Contribution
Pollard, A. S., Charlton, B. G., McGonnell, I. M., & Pitsillides, A. A. IDENTIFYING MECHANISMS AND EVOLUTIONARY IMPLICATIONS OF MECHANOSENSITIVE GROWTH IN THE EMBRYONIC LIMB SKELETON

MECHANOSENSITIVITY OF EMBRYONIC LIMBS: MECHANO-SENSITIVE AND INSENSITIVE PERIODS OF GROWTH, DIFFERENTIAL SENSITIVITY BETWEEN LIMB ELEMENTS, AND THE UNDERPINNING MECHANISMS
Presentation / Conference Contribution
Pollard, A. S., McGonnell, I. M., Chenu, C., Farquharson, C., & Pitsillides, A. A. MECHANOSENSITIVITY OF EMBRYONIC LIMBS: MECHANO-SENSITIVE AND INSENSITIVE PERIODS OF GROWTH, DIFFERENTIAL SENSITIVITY BETWEEN LIMB ELEMENTS, AND THE UNDERPINNING MECHANISMS

SYSTEMATIZING MURINE MENISCAL AND LIGAMENT MODIFICATIONS DURING OSTEOARTHRITIS
Journal Article
Poulet, B., Bou-Gharios, G., & Pitsillides, A. A. SYSTEMATIZING MURINE MENISCAL AND LIGAMENT MODIFICATIONS DURING OSTEOARTHRITIS

FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT
Presentation / Conference Contribution
Ramanayake, W., Jones, H., Orriss, I. R., Arnett, T., Pitsillides, A. A., Denton, C., Abraham, D., & Poulet, B. FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT

E11 PROTEIN STABILISATION BY PROTEASOME INHIBITION PROMOTES OSTEOCYTE DIFFERENTIATION AND MAY PROTECT AGAINST OSTEOARTHRITIS BONE PATHOLOGY
Journal Article
Staines, K. A., Prideaux, M., Hohenstein, P., Buttle, D. J., Pitsillides, A. A., & Farquharson, C. E11 PROTEIN STABILISATION BY PROTEASOME INHIBITION PROMOTES OSTEOCYTE DIFFERENTIATION AND MAY PROTECT AGAINST OSTEOARTHRITIS BONE PATHOLOGY

FAT-HIPPO SIGNALLING IN BONE DEVELOPMENT
Presentation / Conference Contribution
Yiu, C. T., Zakaria, S., Shah, M., Mao, Y., Martin, T., Pitsillides, A. A., Irvine, K. D., & Francis-West, P. FAT-HIPPO SIGNALLING IN BONE DEVELOPMENT

FSTL3: A NOVEL REGULATOR OF GROWTH PLATE DYNAMICS?
Journal Article
Burleigh, A., Staines, K. A., Poulet, B., Pitsillides, A. A., & Mukherjee, A. FSTL3: A NOVEL REGULATOR OF GROWTH PLATE DYNAMICS?

FSTL3: A NOVEL REGULATOR OF GROWTH PLATE DYNAMICS?
Presentation / Conference Contribution
Burleigh, A., Staines, K. A., Poulet, B., Pitsillides, A. A., & Mukherjee, A. FSTL3: A NOVEL REGULATOR OF GROWTH PLATE DYNAMICS?

Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model
Journal Article
Carriero, A., Abela, L., Pitsillides, A. A., & Shefelbine, S. J. Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model. Journal of Biomechanics, 18(47), 2490-2497. https://doi.org/10.1016/j.jbiomech.2014.03.035