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All Outputs (154)

Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages (2018)
Journal Article
Serna, H., Pocknell, A., Sainsbury, A. W., Peniche, G., Blake, D. P., & Beckmann, K. M. (2018). Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages. Avian Pathology, https://doi.org/10.1080/03079457.2018.1451621

Eimeria crecis and Eimeria nenei have been detected in association with enteric disease (‘coccidiosis’) in the corncrake (Crex crex: Family Rallidae, Order Gruiformes). Both parasite species are common in apparently healthy free-living corncrakes, bu... Read More about Eimeria spp. in captive-reared corncrakes (Crex crex): results of GeneScan assay consistent with high prevalence of infection and extra-intestinal life stages.

The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk? (2018)
Journal Article
Rosanowski, S. M., Banica, M., Ellis, E., Farrow, E., Harwood, C., Jordan, B., James, C., McKenna, D., Fox, M. T., & Blake, D. P. (2018). The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk?. Parasitology Research, 117(5), 1663-1667. https://doi.org/10.1007/s00436-018-5857-z

Surveillance was conducted to investigate the occurrence of protozoan parasites of the genus Cryptosporidium in dogs newly admitted to a dog rehoming charity in London, Great Britain. Voided faecal samples were collected from all new admissions betwe... Read More about The molecular characterisation of Cryptosporidium species in relinquished dogs in Great Britain: a novel zoonotic risk?.

Discrimination, molecular characterisation and phylogenetic comparison of porcine Eimeria spp. in India (2018)
Journal Article
Sharma, D., Singh, N. K., Singh, H., Joachim, A., Rath, S. S., & Blake, D. P. (2018). Discrimination, molecular characterisation and phylogenetic comparison of porcine Eimeria spp. in India. Veterinary Parasitology, 255, 43-48. https://doi.org/10.1016/j.vetpar.2018.03.020

Infections with Eimeria spp. are common in pigs worldwide,occasionally affecting animals clinically after weaning or during the fattening period when diarrhoea and weight loss can be observed upon infection with the more pathogenic species. Molecular... Read More about Discrimination, molecular characterisation and phylogenetic comparison of porcine Eimeria spp. in India.

Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens (2018)
Journal Article
Pastor-Fernández, I., Kim, S., Billington, K., Bumstead, J., Marugán-Hernández, V., Küster, T., Ferguson, D. J. P., Vervelde, L., Blake, D. P., & Tomley, F. M. (2018). Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens. International Journal for Parasitology, 48(7), 505-518. https://doi.org/10.1016/j.ijpara.2018.01.003

Recently, the availability of protocols supporting genetic complementation of Eimeria has raised the prospect of generating transgenic parasite lines which can function as vaccine vectors, expressing and delivering heterologous proteins. Complementat... Read More about Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens.

Veterinary Parasitology Teaching at London – Meeting the ‘Day-One Competency’ Needs of New Veterinarians (2018)
Journal Article
Fox, M. T., Blake, D. P., & Jacobs, D. E. (2018). Veterinary Parasitology Teaching at London – Meeting the ‘Day-One Competency’ Needs of New Veterinarians. Veterinary Parasitology, 254, 131-134. https://doi.org/10.1016/j.vetpar.2018.01.029

Over the past four decades, there has been an exponential increase in veterinary parasitology knowledge, coinciding with the advent of molecular biology in research. Therefore, it is unrealistic for teachers to expect students to graduate with an enc... Read More about Veterinary Parasitology Teaching at London – Meeting the ‘Day-One Competency’ Needs of New Veterinarians.

Molecular Identification of Eimeria Species in Broiler Chickens in Trinidad, West Indies (2018)
Journal Article
Brown, J. A., Blake, D. P., Beard, J., Beharry, A., Serrette, L., Soleyn, A., Sookhoo, J., Blake, L., Brown, G., & Oura, C. (2018). Molecular Identification of Eimeria Species in Broiler Chickens in Trinidad, West Indies. Veterinary Sciences, 22(5), 1. https://doi.org/10.3390/vetsci5010012

Coccidiosis is an intestinal disease of chickens of major economic importance to broiler industries worldwide. Species of coccidia found in chickens include Eimeria acervulina, Eimeria brunetti, Eimeria maxima, Eimeria mitis, Eimeria necatrix, Eimeri... Read More about Molecular Identification of Eimeria Species in Broiler Chickens in Trinidad, West Indies.

Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises (2017)
Journal Article
Tang, P. K., Pellett, S., Blake, D. P., & Hedley, J. (2017). Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises. Journal of Herpetological Medicine and Surgery, 27(3-4), 116-122. https://doi.org/10.5818/17-04-107.1

Gastrointestinal parasites are commonly diagnosed in captive tortoises. In response, fenbendazole has traditionally been used as an anthelmintic, either in single or repeated doses. However, fenbendazole requires oral administration and the process c... Read More about Efficacy of a Topical Formulation Containing Emodepside and Praziquantel (Profender®, Bayer) against Nematodes in Captive Tortoises.

A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo (2017)
Journal Article
Silva, L. M. R., Chávez-Maya, F., Macdonald, S., Pegg, E., Blake, D. P., Taubert, A., & Hermosilla, C. (2017). A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo. Veterinary Parasitology, 248, 28-32. https://doi.org/10.1016/j.vetpar.2017.10.014

Coccidiosis caused by Eimeria species is an important disease worldwide, particularly in ruminants and poultry. Eimeria infection can result in significant economic losses due to costs associated with treatment and slower growth rates, or even with m... Read More about A newly described strain of Eimeria arloingi (strain A) belongs to the phylogenetic group of ruminant-infecting pathogenic species, which replicate in host endothelial cells in vivo.

Recombinant anticoccidial vaccines - a cup half full? (2017)
Journal Article
Blake, D. P., Pastor-Fernández, I., Nolan, M. J., & Tomley, F. M. (2017). Recombinant anticoccidial vaccines - a cup half full?. Infection, Genetics and Evolution, 55, 358-365. https://doi.org/10.1016/j.meegid.2017.10.009

Eimeria species parasites can cause the disease coccidiosis, most notably in chickens. The occurrence of coccidiosis is currently controlled through a combination of good husbandry, chemoprophylaxis and/or live parasite vaccination; however, scalable... Read More about Recombinant anticoccidial vaccines - a cup half full?.

Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology (2017)
Journal Article
Macdonald, S. E., Nolan, M. J., Harman, K., Boulton, K., Hume, D. A., Tomley, F. M., Stabler, R. A., & Blake, D. P. (2017). Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology. PLoS ONE, 12(9), e0184890. https://doi.org/10.1371/journal.pone.0184890

Eimeria species cause the intestinal disease coccidiosis, most notably in poultry. While the direct impact of coccidiosis on animal health and welfare is clear, its influence on the enteric microbiota and by-stander effects on chicken health and prod... Read More about Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology.

Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella (2017)
Journal Article
Kundu, K., Garg, R., Kumar, S., Mandal, M., Tomley, F. M., Blake, D. P., & Banerjee, P. S. (2017). Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella. Veterinary Parasitology, 244, 44-53. https://doi.org/10.1016/j.vetpar.2017.07.025

Eimeria tenella, the causative agent of caecal coccidiosis, is a pathogenic gut dwelling protozoan which can cause severe morbidity and mortality in farmed chickens. Immune mapped protein-1 (IMP-1) has been identified as an anticoccidial vaccine cand... Read More about Humoral and cytokine response elicited during immunisation with recombinant Immune Mapped protein-1 (EtIMP-1) and oocysts of Eimeria tenella.

Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle (2017)
Journal Article
Marugan-Hernandez, V., Long, E., Blake, D. P., Crouch, C., & Tomley, F. M. (2017). Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle. https://doi.org/10.1038/s41598-017-04049-1

Eimeria spp. are intracellular parasites that have a major impact on poultry. Effective live vaccines are available and the development of reverse genetic technologies has raised the prospect of using Eimeria spp. as recombinant vectors to express ad... Read More about Eimeria tenella protein trafficking: differential regulation of secretion versus surface tethering during the life cycle.

Are Eimeria Genetically Diverse, and Does It Matter? (2017)
Journal Article
Clark, E. L., Tomley, F. M., & Blake, D. P. (2017). Are Eimeria Genetically Diverse, and Does It Matter?. Trends in Parasitology, 33(3), 231-241. https://doi.org/10.1016/j.pt.2016.08.007

Eimeria pose a risk to all livestock species as a cause of coccidiosis, reducing productivity and compromising animal welfare. Pressure to reduce drug use in the food chain makes the development of cost-effective vaccines against Eimeria essential. F... Read More about Are Eimeria Genetically Diverse, and Does It Matter?.

Eimeria species occurrence varies between geographic regions and poultry production systems and may influence parasite genetic diversity (2017)
Journal Article
Chengat Prakashbabu, B., Thenmozhi, V., Limon, G., Kundu, K., Kumar, S., Garg, R., Clark, E. L., Srinivasa Rao, A. S. R., Raj, D. G., Raman, M., Banerjee, P. S., Tomley, F. M., Guitian, J., & Blake, D. P. (2017). Eimeria species occurrence varies between geographic regions and poultry production systems and may influence parasite genetic diversity. Veterinary Parasitology, 233, 62-72. https://doi.org/10.1016/j.vetpar.2016.12.003

Coccidiosis is one of the biggest challenges faced by the global poultry industry. Recent studies have highlighted the ubiquitous distribution of all Eimeria species which can cause this disease in chickens, but intriguingly revealed a regional divid... Read More about Eimeria species occurrence varies between geographic regions and poultry production systems and may influence parasite genetic diversity.