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All Outputs (31)

Anaesthetic management and complications during hypophysectomy in 37 cats with acromegaly (2018)
Journal Article
Neilson, D. M., Viscasillas, J., Alibhai, H. I. K., Kenny, P. J., Niessen, S. J. M., & Sanchis-Mora, S. (2018). Anaesthetic management and complications during hypophysectomy in 37 cats with acromegaly. Journal of Feline Medicine and Surgery, 21(4), https://doi.org/10.1177/1098612X18778697

The aim of this study was to describe the anaesthetic management and perianaesthetic complications encountered during hypophysectomy surgery in acromegalic cats. We explored relationships between animal demographic data, the anaesthetic protocol used... Read More about Anaesthetic management and complications during hypophysectomy in 37 cats with acromegaly.

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Ventriculo-arterial coupling detects occult RV dysfunction in chronic thromboembolic pulmonary vascular disease (2017)
Journal Article
Axell, R. G., Messer, S. J., White, P. A., McCabe, C., Priest, A., Statopoulou, T., …Hoole, S. P. (2017). Ventriculo-arterial coupling detects occult RV dysfunction in chronic thromboembolic pulmonary vascular disease. Physiological Reports, 5(7), https://doi.org/10.14814/phy2.13227

Chronic thromboembolic disease (CTED) is suboptimally defined by a mean pulmonary artery pressure (mPAP) 0.68 and Ees/Ea < 0.68 subgroups demonstrated constant RV stroke work but lower stroke volume (87.7 ± 22.1 vs. 60.1 ± 16.3 mL respectively, P =... Read More about Ventriculo-arterial coupling detects occult RV dysfunction in chronic thromboembolic pulmonary vascular disease.

Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure (2015)
Journal Article
Baker, L. A., Lee, K. C. L., Jimenez, C. P., Alibhai, H. I. K., Chang, Y. M., Leckie, P. J., …Jalan, R. (2015). Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure. PLoS ONE, 10(5), https://doi.org/10.1371/journal.pone.0128076

Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating the onset of individual organ injury such as the liver, kidneys and brain during the evolution of acute liver failure, a... Read More about Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure.

Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study (2015)
Journal Article
Lee, K. C. L., Baker, L. A., Stanzani, G., Alibhai, H. I. K., Chang, Y. M., Palacios, C. J., …Jalan, R. (2015). Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study. Journal of Hepatology, 63(3), 634-642. https://doi.org/10.1016/j.jhep.2015.04.020

Evaluation of the quality of the recovery after administration of propofol or alfaxalone for induction of anaesthesia in dogs anaesthetized for magnetic resonance imaging
Journal Article
Jiménez, C. P., Mathis, A., Sanchis-Mora, S., Brodbelt, D. C., & Alibhai, H. I. K. Evaluation of the quality of the recovery after administration of propofol or alfaxalone for induction of anaesthesia in dogs anaesthetized for magnetic resonance imaging. Veterinary Anaesthesia and Analgesia, 39(2), 151-159. https://doi.org/10.1111/j.1467-2995.2011.00678.x

A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL
Presentation / Conference Contribution
Lee, K. C. L., Palacios, C. J., Alibhai, H. I. K., Chang, Y. M., Leckie, P., Priestnall, S. L., …Davies, N. A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL. Gut, 61, A186-A186. https://doi.org/10.1136/gutjnl-2012-302514c.8

Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk
Journal Article
Psatha, E., Alibhai, H. I. K., Jimenez-Lozano, A., Armitage-Chan, E., & Brodbelt, D. C. Clinical efficacy and cardiorespiratory effects of alfaxalone, or diazepam/fentanyl for induction of anaesthesia in dogs that are a poor anaesthetic risk. Veterinary Anaesthesia and Analgesia, 38(1), 24-36. https://doi.org/10.1111/j.1467-2995.2010.00577.x

A comparison of the duration and quality of recovery from isoflurane, sevoflurane and desflurane anaesthesia in dogs undergoing magnetic resonance imaging
Journal Article
Lozano, A. J., Brodbelt, D. C., Borer, K. E., Armitage-Chan, E., Clarke, K. W., & Alibhai, H. I. K. A comparison of the duration and quality of recovery from isoflurane, sevoflurane and desflurane anaesthesia in dogs undergoing magnetic resonance imaging. Veterinary Anaesthesia and Analgesia, 36(3), 220-229. https://doi.org/10.1111/j.1467-2995.2009.00451.x

To compare the recovery after anaesthesia with isoflurane, sevoflurane and desflurane in dogs undergoing magnetic resonance imaging (MRI) of the brain. Prospective, randomized clinical trial. Thirty-eight dogs weighing 23.7 +/- 12.6 kg. Following pre... Read More about A comparison of the duration and quality of recovery from isoflurane, sevoflurane and desflurane anaesthesia in dogs undergoing magnetic resonance imaging.

Duration of Effect and Recovery Times, Comparison of Isoflurane, Sevoflurane and Desflurane in dogs undergoing anaesthesia for Magnetic Resonance Imaging (MRI)
Journal Article
Lozano, A. J., Brodbelt, D. C., Borer, K. E., Armitage-Chan, E., Clarke, K., & Alibhai, H. I. K. Duration of Effect and Recovery Times, Comparison of Isoflurane, Sevoflurane and Desflurane in dogs undergoing anaesthesia for Magnetic Resonance Imaging (MRI). Veterinary Anaesthesia and Analgesia, 36, 220-229. https://doi.org/10.1111/j.1467-2995.2009.00451.x

LONGITUDINAL STUDIES OF COAGULATION PROFILE IN THE SYSTEMIC AND PORTAL CIRCULATIONS IN A PORCINE MODEL OF ACETAMINOPHEN INDUCED ACUTE LIVER FAILURE SHOW THAT A HYPERCOAGUABLE STATE PRECEDES A HYPOCOAGUABLE STATE AND IS ASSOCIATED WITH ENDOTOXAEMIA
Presentation / Conference Contribution
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Giordano, P., Leckie, P., …Jalan, R. LONGITUDINAL STUDIES OF COAGULATION PROFILE IN THE SYSTEMIC AND PORTAL CIRCULATIONS IN A PORCINE MODEL OF ACETAMINOPHEN INDUCED ACUTE LIVER FAILURE SHOW THAT A HYPERCOAGUABLE STATE PRECEDES A HYPOCOAGUABLE STATE AND IS ASSOCIATED WITH ENDOTOXAEMIA. Hepatology, 58, 348A-349A