FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT
Journal Article
Ramanayake, W., Jones, H., Orriss, I. R., Arnett, T., Pitsillides, A. A., Denton, C., …Poulet, B. FIBRILLIN-1 IS EXPRESSED IN CARTILAGE AND MUTATION LEADS TO OA DEVELOPMENT. International Journal of Experimental Pathology, 96(2), A4-A5
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The role of purinergic signalling in the musculoskeletal system
Journal Article
Orriss, I. R. (in press). The role of purinergic signalling in the musculoskeletal system. https://doi.org/10.1016/j.autneu.2015.04.013
Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation
Journal Article
Orriss, I. R., Arnett, T. R., George, J., & Witham, M. D. (in press). Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation. Experimental Cell Research, 342(2), 166-174. https://doi.org/10.1016/j.yexcr.2016.03.004
Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebra disc (IVD) degeneration treatment
Journal Article
Serra, T., Capelli, C., Toumpaniari, R., Orriss, I. R., Leong, J., Dalgarno, K., & Kalaskar, D. (in press). Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebra disc (IVD) degeneration treatment. Biofabrication, 8(3), https://doi.org/10.1088/1758-5090/8/3/035001
Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice
Journal Article
Orriss, I. R., Lanham, S. A., Savery, D., Greene, N. D. E., Stanier, P., Oreffo, R., …Galea, G. L. (in press). Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice. https://doi.org/10.1038/s41598-018-21718-xFractures are a common comorbidity in children with the neural tube defect (NTD) spina bifida. Mutations in the Wnt/planar cell polarity (PCP) pathway contribute to NTDs in humans and mice, but whether this pathway independently determines bone mass... Read More about Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.
The in vitro behaviour of canine osteoblasts derived from different bone types
Journal Article
Meeson, R. L., Perpétuo, I. P., Parsons, K. J., Orriss, I. R., Shah, M., Pitsillides, A. A., & Doube, M. (in press). The in vitro behaviour of canine osteoblasts derived from different bone types. BMC Veterinary Research, 15(114), https://doi.org/10.1186/s12917-019-1857-1