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All Outputs (53)

Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation (2020)
Journal Article
Toor, J., Adams, E. R., Aliee, M., Amoah, B., Anderson, R. M., Ayabina, D., …Hollingsworth, T. D. (2020). Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation. Clinical Infectious Diseases, https://doi.org/10.1093/cid/ciaa933

Abstract Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when the NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NT... Read More about Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation.

Designing antifilarial drug trials using clinical trial simulators (2020)
Journal Article
Walker, M., Hamley, J., Milton, P., Monnot, F., Pedrique, B., & Basáñez, M. (2020). Designing antifilarial drug trials using clinical trial simulators. Nature Communications, 11(1), https://doi.org/10.1038/s41467-020-16442-y

Lymphatic filariasis and onchocerciasis are neglected tropical diseases (NTDs) targeted for elimination by mass (antifilarial) drug administration. These drugs are predominantly active against the microfilarial progeny of adult worms. New drugs or co... Read More about Designing antifilarial drug trials using clinical trial simulators.

Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa (2020)
Journal Article
Webster, J. P., Neves, M. I., Webster, B. L., Pennance, T., Rabone, M., Gouvras, A. N., …Rollinson, D. (2020). Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa. American Journal of Tropical Medicine and Hygiene, https://doi.org/10.4269/ajtmh.19-0827

Analyses of the population genetic structure of schistosomes under the “Schistosomiasis Consortium for Operational Research and Evaluation” (SCORE) contrasting treatment pressure scenarios in Tanzania, Niger, and Zanzibar were performed to provide su... Read More about Parasite Population Genetic Contributions to the Schistosomiasis Consortium for Operational Research and Evaluation within Sub-Saharan Africa.

Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools (2020)
Journal Article
Walker, M., Webster, J. P., & Milne, G. (2020). Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools. Clinical Infectious Diseases, https://doi.org/10.1093/cid/ciaa428

Background. Horizontal transmission of Toxoplasma gondii occurs primarily via ingestion of environmental oocysts or con- sumption of undercooked/raw meat containing cyst-stage bradyzoites. The relative importance of these 2 transmission routes remain... Read More about Toward Improving Interventions Against Toxoplasmosis by Identifying Routes of Transmission Using Sporozoite- specific Serological Tools.

Structural Uncertainty in Onchocerciasis Transmission Models Influences the Estimation of Elimination Thresholds and Selection of Age Groups for Seromonitoring (2020)
Journal Article
Hamley, J. I. D., Walker, M., Coffeng, C. E., Milton, P., De Vlas, S. J., Stolk, W. A., & Basáñez, M. (2020). Structural Uncertainty in Onchocerciasis Transmission Models Influences the Estimation of Elimination Thresholds and Selection of Age Groups for Seromonitoring. Journal of Infectious Diseases, https://doi.org/10.1093/infdis/jiz674

Serological Evaluation of Onchocerciasis and Lymphatic Filariasis Elimination in the Bakoye and Falémé foci, Mali (2020)
Journal Article
Basáñez, M., Walker, M., Nutman, T. B., Colebunders, R., Diarra, D., Coulibaly, M. E., …Dolo, H. (2020). Serological Evaluation of Onchocerciasis and Lymphatic Filariasis Elimination in the Bakoye and Falémé foci, Mali. Clinical Infectious Diseases, https://doi.org/10.1093/cid/ciaa318

In Mali, ivermectin-based onchocerciasis elimination from the Bakoye and Falémé foci, reported in 2009–2012, was a beacon leading to policy shifting from morbidity control to elimination of transmission (EOT). These foci are also endemic for lymphati... Read More about Serological Evaluation of Onchocerciasis and Lymphatic Filariasis Elimination in the Bakoye and Falémé foci, Mali.

Situation analysis of onchocerciasis in Cameroon: a protocol for systematic review of epidemiological studies and impact of disease control interventions (2020)
Journal Article
Nana-Djeunga, H. C., Domche, A., Niamsi-Emalio, Y., Moungui, H. C., Walker, M., Basáñez, M., & Kamgno, J. (2020). Situation analysis of onchocerciasis in Cameroon: a protocol for systematic review of epidemiological studies and impact of disease control interventions. Systematic Reviews, 9(27), https://doi.org/10.1186/s13643-020-1287-y

Modelling for Taenia solium control strategies beyond 2020 (2020)
Report
Dixon, M. A., Braae, U. C., Winskill, P., Devleesschauwer, B., Trevisan, C., Van Damme, I., …Basáñez, M. (2020). Modelling for Taenia solium control strategies beyond 2020

The cestode Taenia solium is responsible for a considerable cross-sectoral health and economic burden due to human neurocysticercosis and porcine cysticercosis. The 2012 World Health Organization (WHO) roadmap for neglected tropical diseases called f... Read More about Modelling for Taenia solium control strategies beyond 2020.

Sea lice exposure to non-lethal levels of emamectin benzoate after treatments: a potential risk factor for drug resistance (2020)
Journal Article
Lam, C. T., Rosanowski, S. M., Walker, M., & St-Hilaire, S. (2020). Sea lice exposure to non-lethal levels of emamectin benzoate after treatments: a potential risk factor for drug resistance. https://doi.org/10.1038/s41598-020-57594-7

The avermectin derivative emamectin benzoate (EMB) has been widely used by salmon industries around the world to control sea lice infestations. Resistance to this anti-parasitic drug is also commonly reported in these industries. The objective of thi... Read More about Sea lice exposure to non-lethal levels of emamectin benzoate after treatments: a potential risk factor for drug resistance.

Modelling exposure heterogeneity and density dependence in onchocerciasis using a novel individual-based transmission model, EPIONCHO-IBM: implications for elimination and data needs (2019)
Journal Article
Hamley, J. I. D., Milton, P., Walker, M., & Basáñez, M. (2019). Modelling exposure heterogeneity and density dependence in onchocerciasis using a novel individual-based transmission model, EPIONCHO-IBM: implications for elimination and data needs. PLoS Neglected Tropical Diseases, 13(12), https://doi.org/10.1371/journal.pntd.0007557

The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan (2019)
Journal Article
Neves, M. I., Malkawi, I., Walker, M., Alaboudi, A., Abu-Basha, E., Blake, D. P., …Crotta, M. (2019). The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan. Epidemiology and Infection, 147, E134. https://doi.org/10.1017/S0950268818003308

Campylobacter is the leading cause of foodborne bacterial gastroenteritis in humans worldwide, often associated with the consumption of undercooked poultry. In Jordan, the majority of broiler chicken production occurs in semi-commercial farms, where... Read More about The transmission dynamics of Campylobacter jejuni among broilers in semi-commercial farms in Jordan.

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control (2018)
Journal Article
Verver, S., Walker, M., Kim, Y. E., Fobi, G., Tekle, A. H., Zouré, H. G. M., …Stolk, W. A. (2018). How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control. Clinical Infectious Diseases, 66(4), S267-S274. https://doi.org/10.1093/cid/cix1137

Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa (2018)
Journal Article
Routledge, I., Walker, M., Cheke, R. A., Bhatt, S., Nkot, P. B., Matthews, G. A., …Basáñez, M. (2018). Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa. https://doi.org/10.1186/s13071-018-2864-y

The Population Biology and Transmission Dynamics of Loa loa (2018)
Journal Article
Whittaker, C., Walker, M., Pion, S. D. S., Chesnais, C. B., Boussinesq, M., & Basáñez, M. (2018). The Population Biology and Transmission Dynamics of Loa loa. Trends in Parasitology, https://doi.org/10.1016/j.pt.2017.12.003

Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of publi... Read More about The Population Biology and Transmission Dynamics of Loa loa.

Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing (2017)
Journal Article
Halder, J. B., Benton, J., Julé, A. M., Guérin, P. J., Olliaro, P. L., Basáñez, M., & Walker, M. (2017). Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing. PLoS Neglected Tropical Diseases, 11(10), e0006053. https://doi.org/10.1371/journal.pntd.0006053

Preventive chemotherapy and transmission control (PCT) by mass drug administration is the cornerstone of the World Health Organization (WHO)’s policy to control soil-transmitted helminthiases (STHs) caused by Ascaris lumbricoides (roundworm), Trichur... Read More about Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing.