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Canine Ependymoma: Diagnostic Criteria and Common Pitfalls (2019)
Journal Article
Miller, A. D., Koehler, J. W., Donovan, T. A., Stewart, J. E., Porter, B. F., Rissi, D. R., …Schulman, F. Y. (2019). Canine Ependymoma: Diagnostic Criteria and Common Pitfalls. Veterinary Pathology, 56(6), 860-867. https://doi.org/10.1177/0300985819859872

Reports of canine ependymoma are generally restricted to single case reports with tumor incidence estimated at 2% to 3% of primary central nervous system (CNS) tumors. While most commonly reported in the lateral ventricle, tumors can occur anywhere i... Read More about Canine Ependymoma: Diagnostic Criteria and Common Pitfalls.

Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy (2019)
Journal Article
Swaffield, M., Hedley, J., Stapleton, N., Priestnall, S. L., Suárez-Bonnet, A., & Baldrey, V. (2019). Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy. Journal of Exotic Pet Medicine, https://doi.org/10.1053/j.jepm.2019.05.003

A six-month-old male entire ferret presented for investigation of atraumatic bilateral pelvic limb lameness. Radiographic and subsequent histopathological assessment of the femoral heads following bilateral femoral head ostectomy was consistent with... Read More about Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy.

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases (2019)
Journal Article
Singhania, A., Graham, C. M., Gabryšová, L., Moreira-Teixeira, L., Stavropoulos, E., Pitt, J. M., …O’Garra, A. (2019). Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. Nature Communications, 10, https://doi.org/10.1038/s41467-019-10601-6

Understanding how immune challenges elicit different responses is critical for diagnosing and deciphering immune regulation. Using a modular strategy to interpret the complex transcriptional host response in mouse models of infection and inflammation... Read More about Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome (2019)
Journal Article
Pittaway, R., Dobromylskyj, M. J., Erles, K., Pittaway, C. E., Suárez-Bonnet, A., Chang, Y. M., & Priestnall, S. L. (2019). Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Veterinary Pathology, 56(6), 868-877. https://doi.org/10.1177/0300985819854435

Nonocular melanocytic neoplasia is considered uncommon in cats yet is routinely encountered in diagnostic pathology and recognized to exhibit a wide variation in biological behavior. Accurate prediction of clinical outcomes is challenging with no wid... Read More about Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome.

Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy (2019)
Journal Article
Wennogle, S. A., Priestnall, S. L., Suárez-Bonnet, A., Soontararak, S., & Webb, C. B. (2019). Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15545

Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease (2019)
Journal Article
Allenspach, K., Mochel, J. P., Du, Y., Priestnall, S. L., Moore, F., Slayter, M., …Jergens, A. E. (2019). Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease. Veterinary Pathology, 56(3), 435-443. https://doi.org/10.1177/0300985818813090

Prior studies have failed to detect a convincing association between histologic lesions of inflammation and clinical activity in dogs with inflammatory bowel disease (IBD). We hypothesized that use of a simplified histopathologic scoring system would... Read More about Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease.

Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat (2018)
Journal Article
Stoll, A. L., Suárez-Bonnet, A., Summers, B. A., & Priestnall, S. L. (2018). Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat. Journal of Comparative Pathology, 165, 1-5. https://doi.org/10.1016/j.jcpa.2018.09.003

Divergent differentiation is encountered frequently within human malignant peripheral nerve sheath tumours (MPNSTs). The new component is often a rhabdomyosarcoma, but in animals this specific form of divergent differentiation within MPNSTs has only... Read More about Malignant Cutaneous Peripheral Nerve Sheath Tumour with Rhabdomyosarcomatous Differentiation (Triton Tumour) in a Domestic Cat.

Observational Study Design in Veterinary Pathology, Part 2: Methodology (2018)
Journal Article
Caswell, J. L., Bassel, L. L., Rothenburger, J. L., Gröne, A., Sargeant, J. M., Beck, A. P., …Yamate, J. (2018). Observational Study Design in Veterinary Pathology, Part 2: Methodology. Veterinary Pathology, 55(6), 774-785. https://doi.org/10.1177/0300985818798121

Observational studies are a basis for much of our knowledge of veterinary pathology, yet considerations for conducting pathology-based observational studies are not readily available. In part 1 of this series, we offered advice on planning and carryi... Read More about Observational Study Design in Veterinary Pathology, Part 2: Methodology.

Cutaneous Botryomycosis in Two Pet Rabbits (2018)
Journal Article
Hedley, J., Stapleton, N., Muir, C., Priestnall, S. L., & Smith, K. (2018). Cutaneous Botryomycosis in Two Pet Rabbits. Journal of Exotic Pet Medicine, 28, 143-147. https://doi.org/10.1053/j.jepm.2018.01.005

A 5-year-old male neutered rabbit was presented for assessment of multiple abscesses, which had appeared suddenly over the ventrum, perineum and hindlimbs over the previous few days. Thirteen abscesses were surgically excised. Culture revealed Pseudo... Read More about Cutaneous Botryomycosis in Two Pet Rabbits.

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig (2018)
Journal Article
Wong, H. E., Hedley, J., Stapleton, N., Murphy, B., & Priestnall, S. L. (2018). Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718794784

Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas a... Read More about Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig.

Observational Study Design in Veterinary Pathology, Part 1: Study Design (2018)
Journal Article
Caswell, J. L., Bassel, L. L., Rothenburger, J. L., Gröne, A., Sargeant, J. M., Beck, A. P., …Yamate, J. (2018). Observational Study Design in Veterinary Pathology, Part 1: Study Design. Veterinary Pathology, 55(6), https://doi.org/10.1177/0300985818785705

Observational studies are the basis for much of our knowledge of veterinary pathology and are highly relevant to the daily practice of pathology. However, recommendations for conducting pathology-based observational studies are not readily available.... Read More about Observational Study Design in Veterinary Pathology, Part 1: Study Design.

Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers (2018)
Journal Article
Beever, L., Swinbourne, F., Priestnall, S. L., Ter Haar, G., & Brockman, D. J. (2018). Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers. Journal of Small Animal Practice, 60(4), 254-260. https://doi.org/10.1111/jsap.12839

Three West Highland white terriers were presented for investigation of left‐sided para‐aural abscessation. CT revealed chronic otitis media with extensive osseous proliferation surrounding the horizontal and vertical ear canals contiguous with the ex... Read More about Surgical management of chronic otitis secondary to craniomandibular osteopathy in three West Highland white terriers.

Canine NAPEPLD-associated models of human myelin disorders (2018)
Journal Article
Minor, K. M., Letko, A., Becker, D., Drogemuller, M., Mandigers, P. J. J., Bellekom, S. R., …Drogemuller, C. (2018). Canine NAPEPLD-associated models of human myelin disorders. https://doi.org/10.1038/s41598-018-23938-7

Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to... Read More about Canine NAPEPLD-associated models of human myelin disorders.

Small animal disease surveillance: respiratory disease 2017 (2018)
Journal Article
Arsevska, E., Priestnall, S. L., Singleton, D. A., Jones, P. H., Smyth, S., Brant, B., …Radford, A. D. (2018). Small animal disease surveillance: respiratory disease 2017. Veterinary Record, 182, 369-373. https://doi.org/10.1136/vr.k1426

This report focuses on surveillance for respiratory disease in companion animals. It begins with an analysis of data from 392 veterinary practices contributing to the Small Animal Veterinary Surveillance Network (SAVSNET) between January and December... Read More about Small animal disease surveillance: respiratory disease 2017.

Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry (2018)
Journal Article
Pittaway, R., Wu, Y., Suárez-Bonnet, A., Szladovits, B., Scurrell, E. J., Garden, O. A., …Priestnall, S. L. (2018). Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718760965

Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large pleomorphic cells that express CD30. Null-cell lymphoma has also been described in dogs when neither... Read More about Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry.

Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy (2017)
Journal Article
Carvalho, S., Stoll, A. L., Priestnall, S. L., Suárez-Bonnet, A., Rassnick, K., Lynch, S., …Lara-Garcia, A. (2017). Retrospective evaluation of COX-2 expression, histological and clinical factors as prognostic indicators in dogs with renal cell carcinomas undergoing nephrectomy. Veterinary and Comparative Oncology, 15(4), 1280-1294. https://doi.org/10.1111/vco.12264

14-3-3s Protein Expression in Canine Renal Cell Carcinomas (2017)
Journal Article
Suárez-Bonnet, A., Lara-García, A., Stoll, A. L., Carvalho, S., & Priestnall, S. L. (2017). 14-3-3s Protein Expression in Canine Renal Cell Carcinomas. Veterinary Pathology, 55(2), 233-240. https://doi.org/10.1177/0300985817738097

14-3-3σ is a protein expressed in many epithelial tissues associated with essential cell functions, including cell-cycle control, apoptosis, and cytoskeletal integrity. There is a paucity of knowledge of the tumorigenesis of canine renal cell carcino... Read More about 14-3-3s Protein Expression in Canine Renal Cell Carcinomas.