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All Outputs (154)

Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial (2019)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Upton, N., Volk, H. A., & Pelligand, L. (2019). Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial. https://doi.org/10.1016/j.tvjl.2019.06.006

Pregabalin is the first-line treatment for neuropathic pain (NeP) in humans. Dogs with Chiari-like malformation and syringomyelia (CM/SM) associated with NeP could benefit from pregabalin. The aim of this study was to evaluate the efficacy of pregaba... Read More about Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial.

Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome (2019)
Journal Article
Pittaway, R., Dobromylskyj, M. J., Erles, K., Pittaway, C. E., Suárez-Bonnet, A., Chang, Y. M., & Priestnall, S. L. (2019). Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Veterinary Pathology, 56(6), 868-877. https://doi.org/10.1177/0300985819854435

Nonocular melanocytic neoplasia is considered uncommon in cats yet is routinely encountered in diagnostic pathology and recognized to exhibit a wide variation in biological behavior. Accurate prediction of clinical outcomes is challenging with no wid... Read More about Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome.

Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases (2019)
Journal Article
Dunkel, B., Mason, C. J., & Chang, Y. M. (2019). Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.12851

A recent study described increased l‐lactate concentrations in ponies with gastrointestinal disease compared to horses, but blood glucose (BG) concentrations were not considered. The study tested the hypothesis that BG and l‐lactate concentrations ar... Read More about Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases.

Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study (2019)
Journal Article
Conroy, M. C., Brodbelt, D. C., O'Neill, D. G., Chang, Y. M., & Elliott, J. (2019). Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study. Veterinary Record, 184(17), https://doi.org/10.1136/vr.105100

Chronic kidney disease (CKD) is a frequent diagnosis in cats attending primary care practice and the most frequent cause of death in cats aged over five years, yet there is limited published research for CKD in cats attending primary care practice. T... Read More about Chronic kidney disease in cats attending primary care practice in the UK: a VetCompassTM study.

Visual outcome following phacoemulsification in English Cocker Spaniels with suspected progressive retinal atrophy: A retrospective multicenter study of 54 cases (2002-2017) (2019)
Journal Article
Koll, S., Enache, A., Fenollosa-Romero, E., Chang, Y. M., Busse, C., Oliver, J., …Matas Riera, M. (2019). Visual outcome following phacoemulsification in English Cocker Spaniels with suspected progressive retinal atrophy: A retrospective multicenter study of 54 cases (2002-2017). Veterinary Ophthalmology, https://doi.org/10.1111/vop.12627

Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares (2019)
Journal Article
De Mestre, A. M., Rose, V. B., Chang, Y. M., Wathes, D. C., & Verheyen, K. L. P. (2019). Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares. Theriogenology, 124, 18-23. https://doi.org/10.1016/j.theriogenology.2018.10.008

Early pregnancy loss (EPL) between days 15–65 after breeding has been shown to occur in 7.9% of equine pregnancies with substantial economical, welfare and safety implications. Whilst maternal age has been recognised as an important risk factor in re... Read More about Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares.

Survival after diagnosis of hypertension in cats attending primary care practice in the UK (2018)
Journal Article
Chang, Y. M., Brodbelt, D. C., Elliott, J., & Conroy, M. C. (2018). Survival after diagnosis of hypertension in cats attending primary care practice in the UK. Journal of Veterinary Internal Medicine, 32(6), 1846-1855. https://doi.org/10.1111/jvim.15307

Background: Hypertension is common in older cats. There is limited evidence for predictors of survival after diagnosis. Hypothesis/Objectives: Investigate blood pressure assessment (BPA) and hypertension diagnosis in cats attending UK primary care... Read More about Survival after diagnosis of hypertension in cats attending primary care practice in the UK.

Campylobacter, a zoonotic pathogen of global importance: Prevalence and risk factors in the fast-evolving chicken meat system of Nairobi, Kenya (2018)
Journal Article
Carron, M., Chang, Y. M., Momanyi, K., Akoko, J., Kiiru, J., Bettridge, J. M., …Haesler, B. (2018). Campylobacter, a zoonotic pathogen of global importance: Prevalence and risk factors in the fast-evolving chicken meat system of Nairobi, Kenya. PLoS Neglected Tropical Diseases, 12(8), e0006658. https://doi.org/10.1371/journal.pntd.0006658

Campylobacteriosis is a leading foodborne zoonosis worldwide, and is frequently associated with handling and consumption of poultry meat. Various studies indicate that Campylobacter causes a substantial human disease burden in low to middle-income co... Read More about Campylobacter, a zoonotic pathogen of global importance: Prevalence and risk factors in the fast-evolving chicken meat system of Nairobi, Kenya.

Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice (2018)
Journal Article
Javaheri, B., Razi, H., Piles, M., De Souza, R., Chang, Y. M., Maric-Mur, I., …Pitsillides, A. A. (2018). Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice. Osteoarthritis and Cartilage, 26(6), 807-817. https://doi.org/10.1016/j.joca.2018.03.008

Human osteoarthritis (OA) is detected only at late stages. Male STR/Ort mice develop knee OA spontaneously with known longitudinal trajectory, offering scope to identify OA predisposing factors. We exploit the lack of overt OA in female STR/Ort and i... Read More about Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice.

Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease (2018)
Journal Article
Van Den Broek, D. H. N., Geddes, R. F., Williams, T. L., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease. Journal of Veterinary Internal Medicine, 32(2), 727-735. https://doi.org/10.1111/jvim.15051

Background: Hypercalcemia is commonly associated with chronic kidney disease (CKD) in cats. Objectives: To explore the calcitonin response to naturally occurring ionized hypercalcemia in cats with azotemic CKD, and to assess the relationship of... Read More about Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease.

Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle (2018)
Journal Article
Damaso, A. F., Velasova, M., Van Winden, S. C. L., Chang, Y. M., & Guitian, J. (2018). Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle. Veterinary Record Open, 5, e000221. https://doi.org/10.1136/vetreco-2017-000221

This study describes the occurrence of preterm calving in Great Britain and evaluates its associations with subsequent milk production and reproductive performances and survival on farm of dairy cows. A total of 53 British dairy farms and 5759 animal... Read More about Occurrence of preterm calving in Great Britain and associations with milk production and reproductive performance in dairy cattle.

Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae) (2018)
Journal Article
Michaels, C. J., Das, S., Chang, Y. M., & Tapley, B. (2018). Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae)

Aquatic predators must forage for prey in a complex three-dimensional environment where the availability of different prey types with different spatial niches may vary. Aquatic predators have evolved a number of ways in which they may respond to this... Read More about Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae).

Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013) (2017)
Journal Article
Rosanowski, S. M., Chang, Y. M., Stirk, A. J., & Verheyen, K. L. P. (2017). Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013). Preventive Veterinary Medicine, 148, 58-65. https://doi.org/10.1016/j.prevetmed.2017.10.003

The incidence of race-day injuries in Great Britain (GB) is higher on all-weather (AW) surfaces than on turf. However, to date no studies have focused on identifying risk factors for injury specific to AW racing. Therefore, the objective of the curre... Read More about Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013).

Disease risk analysis and post-release health surveillance for a reintroduction programme: the pool frog Pelophylax lessonae (2017)
Journal Article
Sainsbury, A. W., Chang, Y. M., Ågren, E., Vaughan-Higgins, R. J., McGill, I. S., Molenaar, F., …Foster, J. (2017). Disease risk analysis and post-release health surveillance for a reintroduction programme: the pool frog Pelophylax lessonae. Transboundary and Emerging Diseases, 64(5), 1530-1548. https://doi.org/10.1111/tbed.12545

There are risks from disease in undertaking wild animal reintroduction programmes. Methods of disease risk analysis have been advocated to assess and mitigate these risks, and post‐release health and disease surveillance can be used to assess the eff... Read More about Disease risk analysis and post-release health surveillance for a reintroduction programme: the pool frog Pelophylax lessonae.

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.