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All Outputs (19)

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID) (2025)
Journal Article
Loeffler, A., Cain, C., Ferrer, L., Nishifuji, K., Varjonen, K., Papich, M., Guardabassi, L., Frosini, S., Barker, E., & Weese, S. (2025). Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). Veterinary Dermatology, https://doi.org/10.1111/vde.13365

BackgroundCanine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing.ObjectivesTo provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including... Read More about Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID) (2025)
Journal Article
Loeffler, A., Cain, C., Ferrer, L., Nishifuji, K., Varjonen, K., Papich, M., Guardabassi, L., Frosini, S., Barker, E., & Weese, J. (2025). Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). Veterinary Dermatology, 36(3), 234-282. https://doi.org/10.1111/vde.13342

BackgroundCanine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing.ObjectivesTo provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including... Read More about Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).

Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs (2025)
Journal Article
O'Neill, D., Becker, S. D., Frosini, S.-M., Stapleton, L. E., Hughes, D. M., & Brodbelt, D. C. (2025). Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs. PLoS ONE, 20(2), e0318734. https://doi.org/10.1371/journal.pone.0318734

Standard bodyweights are an essential component of calculations that summarise many
population-level measures in companion animals, including the defined daily doses for
veterinary species (DDDVet) reporting antimicrobial usage. Standard species bo... Read More about Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs.

Dissemination of blaNDM-5-carrying IncX3-type plasmid among non-clonal Escherichia coli strains colonising a dog with a skin infection caused by a carbapenem-resistant Klebsiella pneumoniae, United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S.-M., Amaral, A. J., Loeffler, A., & Pomba, C. (2023). Dissemination of blaNDM-5-carrying IncX3-type plasmid among non-clonal Escherichia coli strains colonising a dog with a skin infection caused by a carbapenem-resistant Klebsiella pneumoniae, United Kingdom. Journal of Infection and Public Health, https://doi.org/10.1016/j.jiph.2023.10.048

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S.-M., Belas, A., Marques, C., da Silva, J. M., Amaral, A. J., Loeffler, A., & Pomba, C. (in press). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J., Amaral, A., Loeffler, A., & Pomba, C. (2023). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Extended-spectrum beta-lactamase (ESBL)- and plasmid-mediated cephalosporinase (AmpC)-producing Enterobacterales (ESBL/AmpC-E) are an increasing healthcare problem in both human and veterinary medicine. The aim of this study was to investigate the po... Read More about Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom.

Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’? (2023)
Journal Article
Frosini, S.-M., Gallow, G., Gibson, A., Menezes, J., Pomba, C., & Loeffler, A. (in press). Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’?. Microbiology Research, https://doi.org/10.3390/microbiolres14010005

Sampling animals for carriage of meticillin-resistant coagulase-positive staphylococci (MRCoPS), considered zoonotic pathogens, can be challenging and time-consuming. Developing methods to identify mecA from non-invasive samples, e.g. faeces, would b... Read More about Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’?.

mcr-1 colistin resistance gene sharing between Escherichia coli from cohabiting dogs and humans, Lisbon, Portugal, 2018 to 2020 (2022)
Journal Article
Menezes, J., Moreira da Silva, J., Frosini, S.-M., Loeffler, A., Weese, S., Perreten, V., Schwarz, S., Telo da Gama, L., Amaral, A. J., & Pomba, C. (2022). mcr-1 colistin resistance gene sharing between Escherichia coli from cohabiting dogs and humans, Lisbon, Portugal, 2018 to 2020. Eurosurveillance, 27(44), https://doi.org/10.2807/1560-7917.es.2022.27.44.2101144

The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households (2022)
Journal Article
Frosini, S.-M., Bond, R., King, R. H., & Loeffler, A. (2022). The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households. Veterinary Dermatology, https://doi.org/10.1111/vde.13118

Background: Following recovery from meticillin-resistant Staphylococcus pseudintermedius (MRSP) infection of any type, dogs may continue to carry MRSP asymptomatically on skin and mucosae, contributing to the spread of this multidrug-resistant, veter... Read More about The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households.

Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA) (2021)
Journal Article
Loeffler, A., Scott, C., & Frosini, S. M. (2021). Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA). Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, 49(06), 437-440. https://doi.org/10.1055/a-1624-0951

Objective Autogenous Staphylococcus pseudintermedius bacterins can reduce prescribing of antimicrobials in the management of canine recurrent pyoderma. However, increasing prevalence of meticillin-resistant, mecA-positive S. pseudintermedius (MRSP) r... Read More about Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA).

Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs (2021)
Journal Article
Frosini, S. M., Bond, R., King, R., Feudi, C., Schwarz, S., & Loeffler, A. (2021). Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs. BMJ Open, https://doi.org/10.1002/vetr.937

Abstract
MRSP is a multidrug-resistant, zoonotic canine pathogen. This study investigated MRSP carriage and clearance through topical antimicrobial therapy and household cleaning in dogs recovered from MRSP infection.
Dogs were swabbed for MRSP c... Read More about Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs.

Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens (2020)
Journal Article
Frosini, S.-M., Bond, R., McCarthy, A., Feudi, C., Schwarz, S., Lindsay, J., & Loeffler, A. (2020). Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens. Microorganisms, https://doi.org/10.3390/microorganisms8122031

Transmission of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus pseudintermedius (MRSP) between people and pets, and their co-carriage, are well-described. Potential exchange of antimicrobial resistance (AM... Read More about Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens.

DIVERSITY OF STAPHYLOCOCCAL SPECIES CULTURED FROM CAPTIVE LIVINGSTONE’S FRUIT BATS (PTEROPUS LIVINGSTONII) AND THEIR ENVIRONMENT (2019)
Journal Article
Fountain, K., Roberts, L., Young, V., Barbon, A., Frosini, S.-M., Lloyd, D. H., & Loeffler, A. (2019). DIVERSITY OF STAPHYLOCOCCAL SPECIES CULTURED FROM CAPTIVE LIVINGSTONE’S FRUIT BATS (PTEROPUS LIVINGSTONII) AND THEIR ENVIRONMENT. Journal of Zoo and Wildlife Medicine, 50(1), 266-269. https://doi.org/10.1638/2018-0121

Livingstone's fruit bats (Pteropus livingstonii) are critically endangered and a captive population has been established as part of the International Union for Conservation of Nature Species Action Plan. The largest colony, in Jersey Zoo, was sampled... Read More about DIVERSITY OF STAPHYLOCOCCAL SPECIES CULTURED FROM CAPTIVE LIVINGSTONE’S FRUIT BATS (PTEROPUS LIVINGSTONII) AND THEIR ENVIRONMENT.

Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius (2017)
Journal Article
Frosini, S.-M., & Bond, R. (2017). Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius. Antibiotics, 6(4), https://doi.org/10.3390/antibiotics6040029

Emergence of multidrug-resistance in Staphylococcus pseudintermedius (SP) has increased interest in topical therapy as an alternative to systemic antibiotics in canine pyoderma. The antifungal imidazole, clotrimazole, is contained in numerous license... Read More about Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius.

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid (2017)
Journal Article
Frosini, S.-M., Bond, R., Loeffler, A., & Larner, J. (2017). Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid. BMC Veterinary Research, 13(345), https://doi.org/10.1186/s12917-017-1270-6

Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic the... Read More about Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid.

Interaction of chlorhexidine with trisEDTA or miconazole in vitro against canine meticillin-resistant and susceptible Staphylococcus pseudintermedius isolates from two UK regions (2016)
Journal Article
Clark, S. M., Schmidt, V. M., Chang, Y. M., Wilson, A., Timofte, D., Bond, R., & Loeffler, A. (2016). Interaction of chlorhexidine with trisEDTA or miconazole in vitro against canine meticillin-resistant and susceptible Staphylococcus pseudintermedius isolates from two UK regions. Veterinary Dermatology, 27(5), 340+. https://doi.org/10.1111/vde.12357

Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: opportunities for topical therapy of canine superficial pyoderma (2015)
Journal Article
Clark, S. M., Loeffler, A., & Bond, R. (2015). Susceptibility in vitro of canine methicillin-resistant and -susceptible staphylococcal isolates to fusidic acid, chlorhexidine and miconazole: opportunities for topical therapy of canine superficial pyoderma. Journal of Antimicrobial Chemotherapy, 70(7), 2048-52. https://doi.org/10.1093/jac/dkv056