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Fracture-induced pain-like behaviours in a femoral fracture mouse model (2021)
Journal Article
Magnusdottir, R., Gohin, S., ter Heegde, F., Hopkinson, M., McNally, I., Fisher, A., …Chenu, C. (2021). Fracture-induced pain-like behaviours in a femoral fracture mouse model. Osteoporosis International, 32(11), 2347-2359. https://doi.org/10.1007/s00198-021-05991-7

This study is the first comprehensive characterisation of the pain phenotype after fracture using both evoked and naturalistic behaviours in adult male and ovariectomised female mice. It also shows that an anti-nerve growth factor (NGF) therapy could... Read More about Fracture-induced pain-like behaviours in a femoral fracture mouse model.

COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION (2021)
Journal Article
Perez, S., Encinoso, M., Morales, M., Arencibia, A., Suarez-Bonnet, A., Gonzalez-Rodriguez, E., & RaduanJaber, J. (2021). COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION. Slovenian Veterinary Research, 58(3), 111-116. https://doi.org/10.26873/SVR-1330-2021

The purpose of this paper was to do a comparative evaluation of the skull of two species of lizards, the Komodo dragon (Varanus komodoensis) and the Green Iguana ( Iguana iguana), by three-dimensional computed tomographic reconstruction. Images provi... Read More about COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION.

Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection (2021)
Journal Article
Al-Neama, R., Bown, K., Blake, D., & Birtles, R. (2021). Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection. Parasitology, 148(5), 623-629. https://doi.org/10.1017/S0031182021000044

Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enter... Read More about Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.

The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia (2021)
Journal Article
Rebecca, F., van den Broek, D., Chang, Y., Biourge, V., Elliott, J., & Jepson, R. (2021). The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia. Journal of Veterinary Internal Medicine, 35(2), 997-1007. https://doi.org/10.1111/jvim.16050

Background Hypercalcemia is commonly observed in cats with azotemic chronic kidney disease (CKD). Dietary phosphate restriction is considered standard of care but may contribute to the development of hypercalcemia. The optimal dietary management stra... Read More about The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia.

Gastroesophageal intussusception and extreme esophageal dilatation secondary to bilateral laryngeal paralysis in a cat (2021)
Journal Article
Tayler, S., Mullowney, D., Lataretu, A., Plested, M., Tuan, J., & Kathrani, A. (2021). Gastroesophageal intussusception and extreme esophageal dilatation secondary to bilateral laryngeal paralysis in a cat. Journal of Veterinary Internal Medicine, 35(2), 1088-1092. https://doi.org/10.1111/jvim.16056

Gastroesophageal intussusception, extreme esophageal dilatation, and laryngeal paralysis are individually rare clinical entities in cats and the simultaneous occurrence in a single animal has not been described. We describe these 3 conditions occurri... Read More about Gastroesophageal intussusception and extreme esophageal dilatation secondary to bilateral laryngeal paralysis in a cat.

A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses (2021)
Journal Article
O'Hara, V., Cowan, A., Riddell, D., Massey, C., Martin, J., & Piercy, R. (2021). A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-86783-1

Horse racing is a popular and financially important industry worldwide and researchers and horse owners are interested in genetic and training influences that maximise athletic performance. An association has been found between the presence of a shor... Read More about A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses.

Pharmacokinetics of Colistin in the Gastrointestinal Tract of Poultry Following Dosing via Drinking Water and Its Bactericidal Impact on Enteric Escherichia coli (2021)
Journal Article
Mead, A., Richez, P., Azzariti, S., & Pelligand, L. (2021). Pharmacokinetics of Colistin in the Gastrointestinal Tract of Poultry Following Dosing via Drinking Water and Its Bactericidal Impact on Enteric Escherichia coli. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.698135

Colistin, a last-line antibiotic of major importance in veterinary medicine and of critical importance in human medicine, is authorized to treat gastrointestinal (enteric) infections caused by non-invasive Escherichia coli in multiple veterinary spec... Read More about Pharmacokinetics of Colistin in the Gastrointestinal Tract of Poultry Following Dosing via Drinking Water and Its Bactericidal Impact on Enteric Escherichia coli.

Differential rotational movement and symmetry values of the thoracolumbosacral region in high-level dressage horses when trotting (2021)
Journal Article
MacKechnie-Guire, R., & Pfau, T. (2021). Differential rotational movement and symmetry values of the thoracolumbosacral region in high-level dressage horses when trotting. PLoS ONE, 16(5), https://doi.org/10.1371/journal.pone.0251144

High-level dressage horses regularly perform advanced movements, requiring coordination and force transmission between front and hind limbs across the thoracolumbosacral region. This study aimed at quantifying kinematic differences in dressage horses... Read More about Differential rotational movement and symmetry values of the thoracolumbosacral region in high-level dressage horses when trotting.

Magnetic resonance imaging of the caudal portion of the digastric muscle in canine idiopathic facial neuropathy (2021)
Journal Article
McGregor, O., Plested, M., & Beltran, E. (2021). Magnetic resonance imaging of the caudal portion of the digastric muscle in canine idiopathic facial neuropathy. Veterinary Radiology and Ultrasound, 62(4), 455-462. https://doi.org/10.1111/vru.12974

Idiopathic is the most common etiology for acute onset of facial neuropathy in dogs with limited number of studies describing MRI characteristics. A retrospective, observational study was performed using archived records, aiming to describe the MRI f... Read More about Magnetic resonance imaging of the caudal portion of the digastric muscle in canine idiopathic facial neuropathy.

Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy (2021)
Journal Article
Hornby, N., Drees, R., Harron, R., Chang, R., Wells, D., & Piercy, R. (2021). Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy. Neuromuscular Disorders, 31(8), 736-751. https://doi.org/10.1016/j.nmd.2021.05.010

The DE50-MD canine model of Duchenne muscular dystrophy (DMD) has a dystrophin gene splice site mutation causing deletion of exon 50, an out-of-frame transcript and absence of dystrophin expression in striated muscles. We hypothesized that the muscul... Read More about Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy.

Treatment failure in hyperthyroid cats after radioiodine (I-131) injection (2021)
Journal Article
Mullowney, D., Chang, Y., Glanemann, B., & Syme, H. (2021). Treatment failure in hyperthyroid cats after radioiodine (I-131) injection. Journal of Veterinary Internal Medicine, 35(4), 1688-1696. https://doi.org/10.1111/jvim.16161

Background There is limited published information on the outcome for cats where total thyroxine concentration (TT4) remains elevated after treatment with radioactive iodine (RAI). Objective To determine the frequency of, and predictors for, subsequen... Read More about Treatment failure in hyperthyroid cats after radioiodine (I-131) injection.

Differential Rotational Movement of the Thoracolumbosacral Spine in High-Level Dressage Horses Ridden in a Straight Line, in Sitting Trot and Seated Canter Compared to In-Hand Trot (2021)
Journal Article
MacKechnie-Guire, R., & Pfau, T. (2021). Differential Rotational Movement of the Thoracolumbosacral Spine in High-Level Dressage Horses Ridden in a Straight Line, in Sitting Trot and Seated Canter Compared to In-Hand Trot. Animals, 11(3), https://doi.org/10.3390/ani11030888

Simple Summary As part of the investigative process of "loss of athletic performance", quantitative data may help veterinary decision making when assessing equine back dysfunction. Ranges of motion of differential rotational movement were quantified... Read More about Differential Rotational Movement of the Thoracolumbosacral Spine in High-Level Dressage Horses Ridden in a Straight Line, in Sitting Trot and Seated Canter Compared to In-Hand Trot.

Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection (2021)
Journal Article
Cole, L., Hardas, A., Priestnall, S., & Tinson, E. (2021). Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection. Journal of Veterinary Emergency and Critical Care, 31(4), 531-536. https://doi.org/10.1111/vec.13063

Objective To describe a case of Waterhouse-Friderichsen syndrome of adrenocortical failure in a cat with Klebsiella spp. infection. Case Summary A 12-year-old male neutered domestic short-haired cat was referred for respiratory failure requiring mech... Read More about Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection.

Sustainable veterinary anaesthesia: single centre audit of oxygen and inhaled anaesthetic consumption and comparisons to a hypothetical model (2021)
Journal Article
McMillan, M. (2021). Sustainable veterinary anaesthesia: single centre audit of oxygen and inhaled anaesthetic consumption and comparisons to a hypothetical model. Journal of Small Animal Practice, 62(6), 420-427. https://doi.org/10.1111/jsap.13316

Objectives Single centre carbon footprint audit of oxygen and inhaled anaesthetic agent consumption. Study design: Retrospective audit with hypothetical intervention. Materials and Methods Records of 100 consecutive anaesthetics were examined. Consum... Read More about Sustainable veterinary anaesthesia: single centre audit of oxygen and inhaled anaesthetic consumption and comparisons to a hypothetical model.

Influence of endocrine disease on l-lactate concentrations in blood of ponies (2021)
Journal Article
Dunkel, B., Knowles, E., Chang, Y., & Menzies-Gow, N. (2021). Influence of endocrine disease on l-lactate concentrations in blood of ponies. Journal of Veterinary Internal Medicine, 35(3), 1582-1588. https://doi.org/10.1111/jvim.16079

Background Blood l-lactate concentrations are higher in people with developing or established diabetes mellitus and insulin resistance. Objectives To investigate whether blood l-lactate concentrations are positively correlated with measures of insuli... Read More about Influence of endocrine disease on l-lactate concentrations in blood of ponies.

Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves (2021)
Journal Article
Almuhanna, A., Cahalan, S., Lane, A., Goodwin, D., Perkins, J., & Piercy, R. (2021). Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves. Equine Veterinary Journal, 53(6), 1188-1198. https://doi.org/10.1111/evj.13403

Background: Horses are affected by various peripheral nerve disorders but defining their aetiology and pathophysiology is hampered by limited understanding of associated morphological and pathological changes and involvement of specific axonal types.... Read More about Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves.

Anaesthetic and perioperative management of a dog with biventricular congestive heart failure and advanced second-degree atrioventricular block (2021)
Journal Article
Foster, A., Seo, J., & Veres-Nyeki, K. (2021). Anaesthetic and perioperative management of a dog with biventricular congestive heart failure and advanced second-degree atrioventricular block. Vet Record Case Reports, 9(3), https://doi.org/10.1002/vrc2.94

A 7-year-old male neutered Cocker Spaniel presented with a 6-h history of severe tachypnoea. Cardiac evaluation revealed advanced second-degree atrioventricular block (2AVB) and biventricular congestive heart failure (CHF). Due to concerns of impendi... Read More about Anaesthetic and perioperative management of a dog with biventricular congestive heart failure and advanced second-degree atrioventricular block.

Acquired cervical scoliosis in two dogs with inflammatory central nervous system disease (2021)
Journal Article
Poad, L., De Decker, S., & Fenn, J. (2021). Acquired cervical scoliosis in two dogs with inflammatory central nervous system disease. Journal of Veterinary Internal Medicine, 35(5), 2421-2426. https://doi.org/10.1111/jvim.16257

Acquired cervical scoliosis previously has been reported in dogs as a clinical sign associated with Chiari-like malformation and syringomyelia but has not been described with inflammatory central nervous system disease. A 9-month-old Flat-Coated Retr... Read More about Acquired cervical scoliosis in two dogs with inflammatory central nervous system disease.

Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines (2021)
Journal Article
Bremner, A., Kim, S., Morris, K., Nolan, M., Borowska, D., Wu, Z., …Vervelde, L. (2021). Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines. Frontiers in Immunology, 12, https://doi.org/10.3389/fimmu.2021.653085

Eimeria maxima is a common cause of coccidiosis in chickens, a disease that has a huge economic impact on poultry production. Knowledge of immunity to E. maxima and the specific mechanisms that contribute to differing levels of resistance observed be... Read More about Kinetics of the Cellular and Transcriptomic Response to Eimeria maxima in Relatively Resistant and Susceptible Chicken Lines.

Equine squamous gastric disease: prevalence, impact and management (2021)
Journal Article
Hewetson, M., & Tallon, R. (2021). Equine squamous gastric disease: prevalence, impact and management. Veterinary Medicine: Research and Reports, https://doi.org/10.2147/VMRR.S235258

This narrative review explores the etiopathogenesis, clinical signs, diagnosis and treatment of ESGD (Equine Squamous Gastric Disease) and discusses the impact of this commonly encountered condition on the equine industry. ESGD refers specifically to... Read More about Equine squamous gastric disease: prevalence, impact and management.