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Evaluation of physical euthanasia for neonatal piglets on-farm (2020)
Journal Article
Dalla Costa, F. A., Gibson, T. J., Oliveira, S. E. O., Gregory, N. G., Coldebella, A., Faucitano, L., …Dalla Costa, O. A. (2020). Evaluation of physical euthanasia for neonatal piglets on-farm. Journal of Animal Science, 98(7), https://doi.org/10.1093/jas/skaa204

Twenty-seven neonate piglets (range from 0.35 to 1.17 kg) were evaluated for the effectiveness of blunt force trauma as a method of on-farm cull. Brainstem function, brain injury, and hemorrhage scores (increasing from 0 to 3) were assessed after str... Read More about Evaluation of physical euthanasia for neonatal piglets on-farm.

Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis (2020)
Journal Article
Holder, A., Garty, R., Elder, C., Mesnard, P., Laquerbe, C., Bartens, M., …Werling, D. (2020). Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis. Frontiers in Microbiology, 11, https://doi.org/10.3389/fmicb.2020.01420

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic zoonotic disease where host genetics is thought to contribute to susceptibility or resistance. One of the genes implicated is the SLC11A1 gene, that encodes for the natural resist... Read More about Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis.

β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression (2020)
Journal Article
Tajadura, V., Hansen, M. H., Smith, J., Charles, H., Rickman, M., Farrell-Dillon, K., …Ferro, A. (2020). β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression. Cell Death and Disease, 11(6), https://doi.org/10.1038/s41419-020-2687-6

Increased endothelial cell (EC) apoptosis is associated with the development of atherosclerotic plaques that develop predominantly at sites exposed to disturbed flow (DF). Strategies to promote EC survival may therefore represent a novel therapeutic a... Read More about β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression.

Suspected congenital hyperinsulinism in a Shiba Inu dog (2020)
Journal Article
Cook, S., McKenna, M., Glanemann, B., Sandhu, R., & Scudder, C. (2020). Suspected congenital hyperinsulinism in a Shiba Inu dog. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15834

A 3-month-old male intact Shiba Inu dog was evaluated for a seizure disorder initially deemed idiopathic in origin. Seizure frequency remained unchanged despite thera- peutic serum phenobarbital concentration and use of levetiracetam. The dog was doc... Read More about Suspected congenital hyperinsulinism in a Shiba Inu dog.

In dogs with metaldehyde intoxication, are benzodiazepines more effective than methocarbamol in relaxing muscles and reducing tremors? (2020)
Journal Article
Liatis, T. (2020). In dogs with metaldehyde intoxication, are benzodiazepines more effective than methocarbamol in relaxing muscles and reducing tremors?. Veterinary Evidence, 5(2), https://doi.org/10.18849/ve.v5i2.292

PICO question In dogs with metaldehyde intoxication, are benzodiazepines (e.g. diazepam, midazolam) more effective than methocarbamol in relaxing muscles and reducing tremors? Clinical bottom line Category of research question Treatm... Read More about In dogs with metaldehyde intoxication, are benzodiazepines more effective than methocarbamol in relaxing muscles and reducing tremors?.

Comparison of Doppler ultrasonic and oscillometric devices (with or without proprietary optimisations) for non-invasive blood pressure measurement in conscious cats (2020)
Journal Article
Cerna, P., Archontakis, P. E., Cheuk, H. O. K., & Gunn-Moore, D. A. (2020). Comparison of Doppler ultrasonic and oscillometric devices (with or without proprietary optimisations) for non-invasive blood pressure measurement in conscious cats. Journal of Feline Medicine and Surgery, 1098612X2093240

Objectives This study compared Doppler and oscillometric (PetMAP+) devices (with or without proprietary optimisations) for the non-invasive measurement of blood pressure in conscious cats. Methods Twenty-three cats were enrolled; however, five w... Read More about Comparison of Doppler ultrasonic and oscillometric devices (with or without proprietary optimisations) for non-invasive blood pressure measurement in conscious cats.

Factors affecting survival to discharge in 53 cats diagnosed with uroabdomen: a single-centre retrospective analysis (2020)
Journal Article
Hornsey, S. J., Halfacree, Z., Kulendra, E., Parker, S., & Kulendra, N. (2020). Factors affecting survival to discharge in 53 cats diagnosed with uroabdomen: a single-centre retrospective analysis. Journal of Feline Medicine and Surgery, 1098612X2093226. https://doi.org/10.1177/1098612X20932267

Objectives The aim of this study was to assess outcomes in cats diagnosed with uroabdomen at a single referral centre. Methods Fifty-three cats diagnosed with uroabdomen at a veterinary teaching hospital were identified between June 2003 and Sep... Read More about Factors affecting survival to discharge in 53 cats diagnosed with uroabdomen: a single-centre retrospective analysis.

Peritoneal fluid accumulation in the femoral canal as a result of a post‐traumatic femoral hydrocele in a mature Warmblood stallion (2020)
Journal Article
Baldwin, C. M., Priestnall, S. L., & McMaster, M. (2020). Peritoneal fluid accumulation in the femoral canal as a result of a post‐traumatic femoral hydrocele in a mature Warmblood stallion. Equine Veterinary Education, https://doi.org/10.1111/eve.13301

The following case report documents the clinical presentation, ultrasonographic appearance, surgical management and outcome of a horse with a traumatic tear extending from the superficial and deep inguinal rings, across the aponeurosis of the externa... Read More about Peritoneal fluid accumulation in the femoral canal as a result of a post‐traumatic femoral hydrocele in a mature Warmblood stallion.

Incidence and risk factors for heat-related illness (heatstroke) in UK dogs under primary veterinary care in 2016 (2020)
Journal Article
Hall, E., Carter, A., & O’Neill, D. (2020). Incidence and risk factors for heat-related illness (heatstroke) in UK dogs under primary veterinary care in 2016. Scientific Reports, 10(1),

As climate change causes global temperatures to rise, heat-related illness, a potentially fatal condition in dogs, will become an ever-greater threat. This study aimed to report the incidence, fatality and canine risk factors of heat-related illness... Read More about Incidence and risk factors for heat-related illness (heatstroke) in UK dogs under primary veterinary care in 2016.

Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities (2020)
Journal Article
D'Anselme, O., Pelligand, L., Veres-Nyeki, K. O., Zaccagnini, A., & Zilberstein, L. (2020). Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities. Veterinary Anaesthesia and Analgesia,

Objectives: There are no standardized methods for teaching anaesthesia in veterinary universities. Our aims were 1) design a holistic audit tool to assess anaesthesia teaching strategies in veterinary universities; 2) to apply the tool to 4 veterina... Read More about Analysis of teaching methods in anaesthesia in the undergraduate curriculum of 4 veterinary universities.

The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond (2020)
Journal Article
Bowen, J., García, E., Darder, P., Argüelles, J., & Fatjó, J. (2020). The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond

The purpose of this study was to investigate the effects of the Spanish confinement for the control of the COVID-19 pandemic on the behavior of pet cats and dogs, and the support that pets provided to their owners. We found that the quality of life o... Read More about The effects of the Spanish COVID-19 lockdown on people, their pets and the human-animal bond.

Full‐field strain of regenerated bone tissue in a femoral fracture model (2020)
Journal Article
KARALI, A., KAO, A., MEESON, R., ROLDO, M., BLUNN, G., & TOZZI, G. (2020). Full‐field strain of regenerated bone tissue in a femoral fracture model. Journal of Microscopy, https://doi.org/10.1111/jmi.12937

The mechanical behavior of regenerated bone tissue during fracture healing is key in determining its ability to withstand physiological loads. However, the strain distribution in the newly formed tissue and how this influences the way a fracture heal... Read More about Full‐field strain of regenerated bone tissue in a femoral fracture model.

The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes (2020)
Journal Article
Bitsi, S. (2020). The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes. Cytokine, 133, 155154. https://doi.org/10.1016/j.cyto.2020.155154

In obesity, macrophages infiltrate peripheral tissues and secrete pro-inflammatory cytokines that impact local insulin sensitivity. Lipopolysaccharide (LPS) and the saturated fatty acid (FA) palmitate polarise macrophages towards a pro-inflammatory p... Read More about The chemokine CXCL16 can rescue the defects in insulin signaling and sensitivity caused by palmitate in C2C12 myotubes.

Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation (2020)
Journal Article
González Medina, S., Hyde, C., Lovera, I., & Piercy, R. J. (2020). Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation. Equine Veterinary Journal, https://doi.org/10.1111/evj.13303

Measurement of hypoglycin A (HGA) and its toxic metabolite, methylenecyclopropylacetic acid (MCPA), in equine serum confirms a diagnosis of atypical myopathy (AM), a pasture‐associated toxic rhabdomyolysis with high mortality linked to the ingestion... Read More about Detection of hypoglycin A and MCPA‐carnitine in equine serum and muscle tissue: optimisation and validation of a LC‐MS based method without derivatisation.

Test, test, test for COVID-19 antibodies: the importance of sensitivity, specificity and predictive powers (2020)
Journal Article
specificity and predictive powers. Public Health, Vol.185, 88-90. https://doi.org/10.1016/j.puhe.2020.06.006

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody tests of varying specificity and sensitivity are now available. For informing individuals whether they have had coronavirus disease 2019 (COVID-19), they need to be very accurate.... Read More about Test, test, test for COVID-19 antibodies: the importance of sensitivity, specificity and predictive powers.

Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival (2020)
Journal Article
Heeley, A., O’Neill, D., Davison, L., Church, D., Corless, E., & Brodbelt, D. (2020). Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival. Canine Medicine and Genetics, 7(1), https://doi.org/10.1186/s40575-020-00087-7

Background: Diabetes mellitus (DM) is an important endocrine disorder of dogs. The objectives of this study were to estimate prevalence and incidence of DM in dogs, and to explore risk factors for DM and the survival of DM cases in primary-care clini... Read More about Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival.