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Lasting organ-level bone mechanoadaptation is unrelated to local strain (2020)
Journal Article
Javaheri, B., Razi, H., Gohin, S., Wylie, S., Chang, Y. M., Salmon, P., …Pitsillides, A. A. (2020). Lasting organ-level bone mechanoadaptation is unrelated to local strain. Science Advances, 6(10), https://doi.org/10.1126/sciadv.aax8301

Bones adapt to mechanical forces according to strict principles predicting straight shape. Most bones are, however, paradoxically curved. To solve this paradox, we used computed tomography–based, four-dimensional imaging methods and computational ana... Read More about Lasting organ-level bone mechanoadaptation is unrelated to local strain.

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., …Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Potential of milk mid-infrared spectra to predict nitrogen use efficiency of individual dairy cows in early lactation (2020)
Journal Article
Grelet, C., Froidmont, E., Foldager, L., Salavati, M., Hostens, M., Ferris, C. P., …Dehareng, F. (2020). Potential of milk mid-infrared spectra to predict nitrogen use efficiency of individual dairy cows in early lactation. Journal of Dairy Science, https://doi.org/10.3168/jds.2019-17910

Improving nitrogen use efficiency (NUE) at both the individual cow and the herd level has become a key target in dairy production systems, for both environmental and economic reasons. Cost-effective and large-scale phenotyping methods are required to... Read More about Potential of milk mid-infrared spectra to predict nitrogen use efficiency of individual dairy cows in early lactation.

Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism (2020)
Journal Article
Boag, A. M., Short, A., Kennedy, L. J., Syme, H., Graham, P. A., & Catchpole, B. (2020). Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism. Canine Medicine and Genetics, 7(2), https://doi.org/10.1186/s40575-020-0081-4

Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison’s disease in humans. Several dog breeds are overrepresented in the disease population, suggesting that a geneti... Read More about Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism.

Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases (2020)
Journal Article
Humm, K. R., & Chan, D. L. (2020). Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases. Journal of Small Animal Practice, 61(5), 285-291. https://doi.org/10.1111/jsap.13124

Objectives To: (1) assess the frequency of crossmatch incompatibility in naïve feline blood transfusion recipients using two crossmatching methods, (2) measure the effect of crossmatch incompatibility on change in packed cell volume following tran... Read More about Prospective evaluation of the utility of cross‐matching prior to first transfusion in cats: 101 cases.

Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta) (2020)
Journal Article
Kunze, P. E., Perrault, J. R., Chang, Y. M., Manire, C. A., Clark, S., & Stacy, N. I. (2020). Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta). PLoS ONE, 15, https://doi.org/10.1371/journal.pone.0229800

Blood glucose is vital for many physiological pathways and can be quantified by clinical chemistry analyzers and in-house point-of-care (POC) devices. Pre-analytical and analytical factors can influence blood glucose measurements. This project aimed... Read More about Pre-analytical factors affecting whole blood and plasma glucose concentrations in loggerhead sea turtles (Caretta caretta).

Aldosterone and the mineralocorticoid receptor in renal injury: A potential therapeutic target in feline chronic kidney disease (2020)
Journal Article
Spencer, S., Wheeler-Jones, C. P. D., & Elliott, J. (2020). Aldosterone and the mineralocorticoid receptor in renal injury: A potential therapeutic target in feline chronic kidney disease. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.12848

There is a growing body of experimental and clinical evidence supporting mineralocorticoid receptor (MR) activation as a powerful mediator of renal damage in laboratory animals and humans. Multiple pathophysiological mechanisms are proposed, with the... Read More about Aldosterone and the mineralocorticoid receptor in renal injury: A potential therapeutic target in feline chronic kidney disease.

Assessing the role of live poultry trade in community-structured transmission of avian influenza in China (2020)
Journal Article
Yang, Q., Zhao, X., Lemey, P., Suchard, M. A., Bi, Y., Shi, W., …Tian, H. (2020). Assessing the role of live poultry trade in community-structured transmission of avian influenza in China. Proceedings of the National Academy of Sciences, 117(11), 5949-5954. https://doi.org/10.1073/pnas.1906954117

The live poultry trade is thought to play an important role in the spread and maintenance of highly pathogenic avian influenza A viruses (HP AIVs) in Asia. Despite an abundance of small-scale observational studies, the role of the poultry trade in di... Read More about Assessing the role of live poultry trade in community-structured transmission of avian influenza in China.

Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry (2020)
Journal Article
Serra Bragança, F. M., Roepstorff, C., Rhodin, M., Pfau, T., Van Weeren, P. R., & Roepstorff, L. (2020). Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry. Biomolecular NMR Assignments, 57, https://doi.org/10.1016/j.bspc.2019.101674

Quantitative gait analysis in horses is rapidly gaining importance, both clinically and in research. The number of available systems is increasing, but the methods of signal analysis differ between systems and research groups. Our objectives are to d... Read More about Quantitative lameness assessment in the horse based on upper body movement symmetry: The effect of different filtering techniques on the quantification of motion symmetry.

Malassezia Yeasts in Veterinary Dermatology: An Updated Overview (2020)
Journal Article
Guillot, J., & Bond, R. (2020). Malassezia Yeasts in Veterinary Dermatology: An Updated Overview. Frontiers in Cellular and Infection Microbiology, 10(79), https://doi.org/10.3389/fcimb.2020.00079

Lipophilic yeasts of the genus Malassezia are important skin commensals and opportunistic skin pathogens in a variety of animals. The species M. pachydermatis was first isolated from the skin of a captive Indian rhinoceros with an exfoliative dermati... Read More about Malassezia Yeasts in Veterinary Dermatology: An Updated Overview.

Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future (2020)
Journal Article
Kapata, N., Ihekweazu, C., Ntoumi, F., Tajudeen, R., Chanda-Kapata, P., Mwaba, P., …Zumla, A. (2020). Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future. International Journal of Infectious Diseases, https://doi.org/10.1016/j.ijid.2020.02.049

Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area (2020)
Journal Article
Nicol, C., Bejder, L., Green, L., Johnson, C., Keeling, L., Noren, D., …Simmonds, M. (2020). Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00057

Human activities and anthropogenic environmental changes are having a profound effect on biodiversity and the sustainability and health of many populations and species of wild mammals. There has been less attention devoted to the impact of human acti... Read More about Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area.

Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America (2020)
Journal Article
Haider, N., Yavlinsky, A., Simons, D., Osman, A. Y., Ntoumi, F., Zumla, A., & Kock, R. A. (2020). Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America. Epidemiology and Infection, 148, https://doi.org/10.1017/S0950268820000424

Novel Coronavirus (2019-nCoV [SARS-COV-2]) was detected in humans during the last week of December 2019 at Wuhan city in China, and caused 24 554 cases in 27 countries and territories as of 5 February 2020. The objective of this study was to estimate... Read More about Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America.

Poultry Coccidiosis: Design and Interpretation of Vaccine Studies (2020)
Journal Article
Soutter, F., Werling, D., Tomley, F. M., & Blake, D. P. (2020). Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00101

Eimeria infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost 70 years, but the requirement to formulate blends of oocysts from multiple Eimeria s... Read More about Poultry Coccidiosis: Design and Interpretation of Vaccine Studies.

Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro (2020)
Journal Article
Kafarnik, C., McClellan, A., Dziasko, M., Daniels, J. T., & Guest, D. J. (2020). Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro. Stem Cells and Development, 29(7), https://doi.org/10.1089/scd.2019.0163

The objective of this study was to determine whether corneal stromal cells (CSCs) from the limbal and central corneal stroma in dogs have multipotent mesenchymal stem/stromal cell (MSC) properties, and whether this cell population can be differentiat... Read More about Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro.

Mammalian lectin arrays for screening host-microbe interactions (2020)
Journal Article
Jégouzo, S. A. F., Nelson, C., Hardwick, T., Wong, S. T. A., Lau, N. K. K., Neoh, G. K. E., …Drickamer, K. (2020). Mammalian lectin arrays for screening host-microbe interactions. Journal of Biological Chemistry, 295(14), 4541-4555. https://doi.org/10.1074/jbc.RA120.012783

Many members of the C-type lectin family of glycan-binding receptors have been ascribed roles in the recognition of microorganisms and serve as key receptors in the innate immune response to pathogens. Other mammalian receptors have become targets th... Read More about Mammalian lectin arrays for screening host-microbe interactions.

The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India (2020)
Journal Article
Mangtani, P., Berry, I., Beauvais, W., Holt, H. R., Kulashri, A., Bharti, S., …Kumar, R. (2020). The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India. Transactions of The Royal Society of Tropical Medicine and Hygiene, https://doi.org/10.1093/trstmh/trz133

Brucellosis is an important neglected zoonosis. Effective cattle vaccines are available but are infrequently used in India, where rural households commonly own one or two cattle as sources of protein and income. We assessed the prevalence of infectio... Read More about The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India.