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MEF2 transcription factors are key regulators of sprouting angiogenesis (2016)
Journal Article
Sacilotto, N., Chouliaras, K. M., Nikitenko, L. L., Lu, Y. W., Fritzsche, M., Wallace, M. D., Nornes, S., García-Moreno, F., Payne, S., Bridges, E., Liu, K., Biggs, D., Ratnayaka, I., Herbert, S. P., Molnár, Z., Harris, A. L., Davies, B., Bond, G. L., Bou-Gharios, G., Schwarz, J. J., & De Val, S. (2016). MEF2 transcription factors are key regulators of sprouting angiogenesis. Genes and Development, 30(20), 2297-2309. https://doi.org/10.1101/gad.290619.116

Angiogenesis, the fundamental process by which new blood vessels form from existing ones, depends on precise spatial and temporal gene expression within specific compartments of the endothelium. However, the molecular links between proangiogenic sign... Read More about MEF2 transcription factors are key regulators of sprouting angiogenesis.

Role for migratory wild birds in the global spread of avian influenza (2016)
Journal Article
The Global Consortium For H5N8 And Related Influenza Viruses. (2016). Role for migratory wild birds in the global spread of avian influenza. Science, 354(6309), 213-217. https://doi.org/10.1126/science.aaf8852

Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014–2015. Our analysis of H5N8 viral sequenc... Read More about Role for migratory wild birds in the global spread of avian influenza.

Monomeric alpha-synuclein exerts a physiological role in brain ATP synthase (2016)
Journal Article
Ludtmann, M. H. R., Angelova, P. R., Ninkina, N., Gandhi, S., Buchman, V. L., & Abramov, A. Y. (2016). Monomeric alpha-synuclein exerts a physiological role in brain ATP synthase. Journal of Neuroscience, 36(41), 10510-10521. https://doi.org/10.1523/JNEUROSCI.1659-16.2016

Misfolded α-synuclein is a key factor in the pathogenesis of Parkinson's disease (PD). However, knowledge about a physiological role for the native, unfolded α-synuclein is limited. Using brains of mice lacking α-, β-, and γ-synuclein, we report that... Read More about Monomeric alpha-synuclein exerts a physiological role in brain ATP synthase.

Development and evaluation of a Markov model to predict changes in schistosomiasis prevalence in response to praziquantel treatment: a case study of Schistosoma mansoni in Uganda and Mali (2016)
Journal Article
Deol, A., Webster, J. P., Walker, M., Basáñez, M.-G., Hollingsworth, T. D., Fleming, F. M., Montresor, A., & French, M. D. (2016). Development and evaluation of a Markov model to predict changes in schistosomiasis prevalence in response to praziquantel treatment: a case study of Schistosoma mansoni in Uganda and Mali. https://doi.org/10.1186/s13071-016-1824-7

Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries (2016)
Journal Article
Garvican, E. R., Salavati, M., Smith, R. K. W., & Dudhia, J. (2016). Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries. Connective Tissue Research, 58(5), 438-446. https://doi.org/10.1080/03008207.2016.1245726

Aim: The purpose of this study was to investigate the effect of normal synovial fluid (SF) on exposed endogenous tendon-derived cells (TDC) and engrafted mesenchymal stem cells (MSCs) within the tendon extracellular matrix.
Methods: Explants from eq... Read More about Exposure of a tendon extracellular matrix to synovial fluid triggers endogenous and engrafted cell death: A mechanism for failed healing of intrathecal tendon injuries.

Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR (2016)
Journal Article
Seeker, L. A., Holland, R., Underwood, S., Fairlie, J., Psifidi, A., Ilska, J. J., Bagnall, A., Whitelaw, B., Coffey, M., Banos, G., & Nussey, D. H. (2016). Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR. PLoS ONE, https://doi.org/10.1371/journal.pone.0164046

Telomere length (TL) is increasingly being used as a biomarker in epidemiological, biomedical and ecological studies. A wide range of DNA extraction techniques have been used in telomere experiments and recent quantitative PCR (qPCR) based studies su... Read More about Method specific calibration corrects for DNA extraction method effects on relative telomere length measurements by quantitative PCR.

Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets (2016)
Journal Article
Moraes, L. A., Unsworth, A. J., Vaiyapuri, S., Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P., Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D., & Gibbins, J. M. (2016). Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets. Arteriosclerosis, Thrombosis, and Vascular Biology, 36(12), 2324-2333. https://doi.org/10.1161/ATVBAHA.116.308093

Foot pressure distributions during walking in African elephants (Loxodonta africana) (2016)
Journal Article
Panagiotopoulou, O., Pataky, T. C., Day, M., Hensman, S., Hutchinson, J. R., & Clemente, C. J. (2016). Foot pressure distributions during walking in African elephants (Loxodonta africana). Royal Society Open Science, 3(10), 160203. https://doi.org/10.1098/rsos.160203

Elephants, the largest living land mammals, have evolved a specialized foot morphology to help reduce locomotor pressures while supporting their large body mass. Peak pressures that could cause tissue damage are mitigated passively by the anatomy of... Read More about Foot pressure distributions during walking in African elephants (Loxodonta africana).

High-intensity cardiac infections of Phthinomita heinigerae n. sp (Digenea: Aporocotylidae) in the orangelined cardinalfish, Taeniamia fucata (Cantor), off Heron Island on the Great Barrier Reef (2016)
Journal Article
Nolan, M. J., Cantacessi, C., Cutmore, S. C., Cribb, T. H., & Miller, T. L. (2016). High-intensity cardiac infections of Phthinomita heinigerae n. sp (Digenea: Aporocotylidae) in the orangelined cardinalfish, Taeniamia fucata (Cantor), off Heron Island on the Great Barrier Reef. Parasitology International, 65(5), 371-377. https://doi.org/10.1016/j.parint.2016.05.006

Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion (2016)
Journal Article
Fenn, J. T., Drees, R., Volk, H. A., & De Decker, S. (2016). Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion. Journal of the American Veterinary Medical Association, 249(7), 767-775. https://doi.org/10.2460/javma.249.7.767

Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes (2016)
Journal Article
Psifidi, A., Banos, G., Matika, O., Desta, T. T., Bettridge, J., Hume, D. A., Tadelle, D., Christley, R., Wigley, P., Hanotte, O., & Kaiser, P. (2016). Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes. Genetics Selection Evolution, 48(74), https://doi.org/10.1186/s12711-016-0252-7

The majority of chickens in sub-Saharan Africa are indigenous ecotypes, well adapted to the local environment and raised in scavenging production systems. Although they are generally resilient to disease challenge, routine vaccination and biosecurity... Read More about Genome-wide association studies of immune, disease and productivity traits in indigenous chicken ecotypes.

Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study - A Randomized Clinical Trial (2016)
Journal Article
Boswood, A., Haggstrom, J., Gordon, S. G., Wess, G., Stepien, R. L., Oyama, M. A., Keene, B. W., Bonagura, J. D., MacDonald, K. A., Patteson, M., Smith, S., Fox, P. R., Sanderson, K., Woolley, R., Szatmari, V., Menaut, P., Church, W. M., O'Sullivan, M. L., Jaudon, J. P., Kresken, J. G., …Watson, P. (2016). Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study - A Randomized Clinical Trial. Journal of Veterinary Internal Medicine, 30(6), 1765-1779. https://doi.org/10.1111/jvim.14586