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All Outputs (412)

Evaluation of radiography as a screening method for detection and characterisation of congenital vertebral malformations in dogs (2018)
Journal Article
Brocal, J., De Decker, S., José-López, R., Guevar, J., Ortega, M., Parkin, T., …Gutierrez-Quintana, R. (2018). Evaluation of radiography as a screening method for detection and characterisation of congenital vertebral malformations in dogs. Veterinary Record, 182(573), https://doi.org/10.1136/vr.104388

Congenital vertebral malformations (CVM) are common in brachycephalic ‘screw-tailed’ dogs; they can be associated with neurological deficits and a genetic predisposition has been suggested. The purpose of this study was to evaluate radiography as a s... Read More about Evaluation of radiography as a screening method for detection and characterisation of congenital vertebral malformations in dogs.

Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum (2018)
Journal Article
Soutter, F., Martorell, S., Solano-Gallego, L., & Catchpole, B. (2018). Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum. https://doi.org/10.1016/j.tvjl.2018.03.001

The clinical outcome of Leishmania infantum infection in dogs varies from subclinical infection to severe disease. Researchers attribute this variability in clinical manifestations to the ability of the immune response to limit pathogen multiplicatio... Read More about Inconsistent MHC class II association in Beagles experimentally infected with Leishmania infantum.

Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens (2018)
Journal Article
Pastor-Fernández, I., Kim, S., Billington, K., Bumstead, J., Marugán-Hernández, V., Küster, T., …Tomley, F. M. (2018). Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens. International Journal for Parasitology, 48(7), 505-518. https://doi.org/10.1016/j.ijpara.2018.01.003

Recently, the availability of protocols supporting genetic complementation of Eimeria has raised the prospect of generating transgenic parasite lines which can function as vaccine vectors, expressing and delivering heterologous proteins. Complementat... Read More about Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens.

A systems approach to evaluate One Health initiatives (2018)
Journal Article
Ruegg, S. R., Nielsen, L. R., Buttigieg, S. C., Santa, M., Aragrande, M., Canali, M., …Haesler, B. (2018). A systems approach to evaluate One Health initiatives. Frontiers in Veterinary Science, 5(23), https://doi.org/10.3389/fvets.2018.00023

Challenges calling for integrated approaches to health, such as the One Health (OH) approach, typically arise from the intertwined spheres of humans, animals, and ecosystems constituting their environment. Initiatives addressing such wicked problems... Read More about A systems approach to evaluate One Health initiatives.

Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009–2014) (2018)
Journal Article
Harris, G. L., Brodbelt, D. C., Church, D. B., Humm, K. R., McGreevy, P. D., Thomson, P. C., & O'Neill, D. G. (2018). Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009–2014). Journal of Veterinary Emergency and Critical Care, 28(2), 140-148. https://doi.org/10.1111/vec.12704

Electronic patient records of dogs attending practices participating in the VetCompass Programme were assessed against selection criteria used to define RTA cases. Cases identified as RTAs were identified and manually verified to calculate prevalence... Read More about Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009–2014).

Immunolocalization of angiogenic growth factors in the ovine uterus during the oestrus cycle and in response to Steroids (2018)
Journal Article
Tremaine, T. D., & Fouladi-Nashta, A. A. (2018). Immunolocalization of angiogenic growth factors in the ovine uterus during the oestrus cycle and in response to Steroids. Reproduction in Domestic Animals, 53(3), 667-679. https://doi.org/10.1111/rda.13156

The vascular changes associated with endometrial maturation in preparation for embryo implantation depend on numerous growth factors, known to regulate key angiogenic events. Primarily, the vascular endothelial growth factor (VEGF) family promotes va... Read More about Immunolocalization of angiogenic growth factors in the ovine uterus during the oestrus cycle and in response to Steroids.

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) (2018)
Journal Article
Stolp, H. B., Ball, G., So, P., Tournier, J., Jones, M., Thornton, C., & Edwards, A. D. (2018). Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND). https://doi.org/10.1038/s41598-018-22295-9

A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology. We present a new tec... Read More about Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND).

Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis (2018)
Journal Article
Verbiest, T., Finnon, P., Brown, N., Cruz-Garcia, L., Finnon, P., O'Brien, G., …Badie, C. (2018). Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis. Nature, 32, 1435-1444. https://doi.org/10.1038/s41375-018-0085-1

Epidemiological studies have demonstrated an increased leukemia incidence following ionizing radiation exposure, but to date, the target cells and underlying mechanisms of radiation leukemogenesis remain largely unidentified. We engineered a mouse mo... Read More about Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis.

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy (2018)
Journal Article
Charalambous, M., Pakozdy, A., Bhatti, S. F. M., & Volk, H. A. (2018). Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy. BMC Veterinary Research, 14(64), https://doi.org/10.1186/s12917-018-1386-3

Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease. However, there is a lack of information about the treatment of feline epilepsy and th... Read More about Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy.

Arthroscopic treatment for cervical articular process joint osteochondrosis in a Thoroughbred horse (2018)
Journal Article
Tucker, R., Piercy, R. J., Dixon, J. J., Muir, C. F., Smith, K. C., Potter, K. E., …Smith, R. K. W. (2018). Arthroscopic treatment for cervical articular process joint osteochondrosis in a Thoroughbred horse. Equine Veterinary Education, 30(3), 116-121. https://doi.org/10.1111/eve.12610

A yearling Thoroughbred colt was presented for investigation of neck stiffness and episodes of intermittent neck pain without neurological signs. Osteochondrosis (OCD) of the cervical articular process joints (APJs) was diagnosed with the aid of radi... Read More about Arthroscopic treatment for cervical articular process joint osteochondrosis in a Thoroughbred horse.

Sedative effects of intramuscular alfaxalone in pet guinea pigs (Cavia porcellus) (2018)
Journal Article
D'Ovidio, D., Marino, F., Noviello, E., Lanaro, E., Monticelli, P., & Adami, C. (2018). Sedative effects of intramuscular alfaxalone in pet guinea pigs (Cavia porcellus). Veterinary Anaesthesia and Analgesia, 45(2), 183-189. https://doi.org/10.1016/j.vaa.2017.08.004

Objective: To evaluate the efficacy and side effects of alfaxalone administered intramuscularly (IM) as a sedative agent in guinea pigs undergoing survey radiographs.

Brucellosis in West and Central Africa: A review of the current situation in a changing landscape of dairy cattle systems (2018)
Journal Article
Craighead, L., Meyer, A., Chengat, B., Musallam, I., Akakpo, J., Kone, P., …Haesler, B. (2018). Brucellosis in West and Central Africa: A review of the current situation in a changing landscape of dairy cattle systems. Acta Tropica, 179, 96-108. https://doi.org/10.1016/j.actatropica.2017.12.026

Brucellosis is a neglected endemic zoonosis in West and Central Africa. In this narrative review, evidence of livestock and human infection is presented along with details of past and current control strategies in 14 selected countries. Data from ava... Read More about Brucellosis in West and Central Africa: A review of the current situation in a changing landscape of dairy cattle systems.

Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures (2018)
Journal Article
Bate, C., & Williams, A. (2018). Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures. Neurobiology of Disease, 111, 48-58. https://doi.org/10.1016/j.nbd.2017.12.007

Alzheimer's disease is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) in the brain. Aβ oligomers are believed to cause synapse damage resulting in the memory deficits that are characteristic of this diseas... Read More about Monomeric amyloid-ß reduced amyloid-ß oligomer-induced synapse damage in neuronal cultures.

Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation (2018)
Journal Article
McAulay, G., Borgeat, K. A., Sargent, J., Mõtsküla, P., Neves, J., Dukes-McEwan, J., & Fuentes, V. L. (2018). Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation. https://doi.org/10.1016/j.tvjl.2018.02.015

The aim of this study was to describe the clinical phenotype of Dogue de Bordeaux (DdB) referred for cardiac investigation, with particular reference to the prevalence of atrial fibrillation and associated features. Review of canine medical records o... Read More about Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation.