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All Outputs (412)

Quantitative Outcomes of a One Health approach to Study Global Health Challenges (2018)
Journal Article
Falzon, L. C., Lechner, I., Chantziaras, I., Collineau, L., Courcoul, A., Filippitzi, M. E., …Brennan, M. L. (2018). Quantitative Outcomes of a One Health approach to Study Global Health Challenges. EcoHealth,

Having gained momentum in the last decade, the One Health initiative promotes a holistic approach to address complex global health issues. Before recommending its adoption to stakeholders, however, it is paramount to first compile quantitative eviden... Read More about Quantitative Outcomes of a One Health approach to Study Global Health Challenges.

Brucellosis remains a neglected disease inthe developing world: a call forinterdisciplinary action (2018)
Journal Article
Franc, K. A., Krecek, R. C., Haesler, B., & Arenas-Gamboa, A. M. (2018). Brucellosis remains a neglected disease inthe developing world: a call forinterdisciplinary action. BMC Public Health, 18(125), https://doi.org/10.1186/s12889-017-5016-y

Brucellosis places significant burdens on the human healthcare system and limits the economic growth of individuals, communities, and nations where such development is especially important to diminish the prevalence of poverty. The implementation of... Read More about Brucellosis remains a neglected disease inthe developing world: a call forinterdisciplinary action.

Ventral Slot Surgery to Manage Cervical Intervertebral Disc Disease in Three Cats (2018)
Journal Article
Crawford, A. H., Cappello, R., Alexander, A., & De Decker, S. (2018). Ventral Slot Surgery to Manage Cervical Intervertebral Disc Disease in Three Cats. Veterinary and Comparative Orthopaedics and Traumatology, 31(1), 71-76. https://doi.org/10.3415/vcot-17-05-0074

This is a retrospective case series evaluating client-owned cats undergoing a ventral slot surgical procedure to manage cervical intervertebral disc disease (n = 3).

The Population Biology and Transmission Dynamics of Loa loa (2018)
Journal Article
Whittaker, C., Walker, M., Pion, S. D. S., Chesnais, C. B., Boussinesq, M., & Basáñez, M. (2018). The Population Biology and Transmission Dynamics of Loa loa. Trends in Parasitology, https://doi.org/10.1016/j.pt.2017.12.003

Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of publi... Read More about The Population Biology and Transmission Dynamics of Loa loa.

Mitochondrial calcium imbalance in Parkinson's disease (2018)
Journal Article
Ludtmann, M. H. R., & Abramov, A. Y. (2018). Mitochondrial calcium imbalance in Parkinson's disease. Neuroscience Letters, 663, 8690. https://doi.org/10.1016/j.neulet.2017.08.044

Multiple factors are involved in the mechanism(s) of neuronal loss in neurodegenerative disorders whilst mitochondria are thought to play a central role in neurodegeneration of Parkinson’s disease. Mitochondria are vital to cellular functions by supp... Read More about Mitochondrial calcium imbalance in Parkinson's disease.

The effect of electromagnetic fields on postoperative pain and locomotor recovery in dogs with acute, severe thoracolumbar intervertebral disc extrusion: a randomized placebo-controlled, prospective clinical trial. (2018)
Journal Article
Zidan, N., Fenn, J., Griffith, E., Early, P., Mariani, C. L., Munana, K. R., …Olby, N. J. (2018). The effect of electromagnetic fields on postoperative pain and locomotor recovery in dogs with acute, severe thoracolumbar intervertebral disc extrusion: a randomized placebo-controlled, prospective clinical trial. Journal of Neurotrauma, 35(15), https://doi.org/10.1089/neu.2017.5485

Spinal cord injury (SCI) due to acute intervertebral disc extrusions (IVDE) is common in dogs and is treated by surgical decompression. Dogs with sensorimotor complete injuries have an incomplete recovery. Pulsed electromagnetic fields (PEMF) reduce... Read More about The effect of electromagnetic fields on postoperative pain and locomotor recovery in dogs with acute, severe thoracolumbar intervertebral disc extrusion: a randomized placebo-controlled, prospective clinical trial..

In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae (2018)
Journal Article
Antenucci, F., Fougeroux, C., Deeney, A., Orskov, C., Rycroft, A. N., Holst, P. J., & Bojesen, A. M. (2018). In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae. Veterinary Research, 49, 4. https://doi.org/10.1186/s13567-017-0502-x

Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is a Gram-negative bacterium that represents the main cause of porcine pleuropneumonia in pigs, causing significant economic losses to the livestock industry worldwide. A. pleuropneumoniae, as the... Read More about In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae.

Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales (2018)
Journal Article
Grierson, S. S., Werling, D., Bidewell, C., & Williamson, S. (2018). Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales. Veterinary Record, 182(1), 22. https://doi.org/10.1136/vr.104450

Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed. The authors carried out a genotyping... Read More about Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales.

Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs (2018)
Journal Article
De Souza, M. C. C. M. I., Ryan, R., Ter Haar, G., Packer, R. M. A., Volk, H. A., & De Decker, S. (2018). Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs. BMC Veterinary Research, 14, 5. https://doi.org/10.1186/s12917-017-1316-9

Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and int... Read More about Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs.

Description of a new approach for great auricular and auriculotemporal nerve blocks: A cadaveric study in foxes and dogs (2018)
Journal Article
Stathopoulou, T., Pinelas, R., Ter Haar, G., Cornelis, I., & Viscasillas, J. (2018). Description of a new approach for great auricular and auriculotemporal nerve blocks: A cadaveric study in foxes and dogs. Veterinary Medicine and Science, 4(2), 91-97. https://doi.org/10.1002/vms3.90

Otitis externa is a painful condition that may require surgical intervention in dogs. A balanced analgesia protocol should combine systemic analgesic agents and local anaesthesia techniques. The aim of the study was to find anatomical landmarks for t... Read More about Description of a new approach for great auricular and auriculotemporal nerve blocks: A cadaveric study in foxes and dogs.

Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs (2018)
Journal Article
Brockmeier, S. L., Loving, C. L., Nicholson, T. L., Wang, J., Peters, S. E., Weinert, L., …Tucker, A. W. (2018). Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs. Infection and Immunity, 86(3), e00559. https://doi.org/10.1128/IAI.00559-17

Streptococcus suis is a bacterium that is commonly carried in the respiratory tract and that is also one of the most important invasive pathogens of swine, commonly causing meningitis, arthritis, and septicemia. Due to the existence of many serotypes... Read More about Use of proteins identified through a functional genomic screen to develop a protein subunit vaccine that provides significant protection against virulent Streptococcus suis in pigs.

Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells (2018)
Journal Article
Williams, R. S. B., & Bate, C. (2018). Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells. Neuropharmacology, 128, 54-62. https://doi.org/10.1016/j.neuropharm.2017.09.031

The amyloid hypothesis of Alzheimer's disease suggests that synaptic degeneration and pathology is caused by the accumulation of amyloid-β (Aβ) peptides derived from the amyloid precursor protein (APP). Subsequently, soluble Aβ oligomers cause the lo... Read More about Valproic acid and its congener propylisopropylacetic acid reduced the amount of soluble amyloid-ß oligomers released from 7PA2 cells.

Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia (2018)
Journal Article
Tsai, H. P., Middleton, K. M., Hutchinson, J. R., & Holliday, C. M. (2018). Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia. Journal of Vertebrate Paleontology, 38(1), https://doi.org/10.1080/02724634.2017.1427593

Dinosauromorphs evolved a wide diversity of hind limb skeletal morphologies, suggesting highly divergent articular soft tissue anatomies. However, poor preservation of articular soft tissues in fossils has hampered any follow-on functional inferences... Read More about Hip joint articular soft tissues of non-dinosaurian Dinosauromorpha and early Dinosauria: evolutionary and biomechanical implications for Saurischia.

Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy (2018)
Journal Article
Packer, R. M. A., McGreevy, P. D., Pergande, A., & Volk, H. A. (2018). Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy. Applied Animal Behaviour Science, 200, 106-113. https://doi.org/10.1016/j.applanim.2017.11.008

Epilepsy and anti-epileptic drug (AED) treatment have been found to induce or exacerbate underlying cognitive impairments in people, affecting learning ability, attention and memory. Idiopathic epilepsy (IE) is the most common chronic neurological co... Read More about Negative effects of epilepsy and antiepileptic drugs on the trainability of dogs with naturally occurring idiopathic epilepsy.

Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya (2018)
Journal Article
Onono, J. O., Alarcon, P., Karani, M., Muinde, P., Akoko, J. M., Maud, C., …Rushton, J. (2018). Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya. Agricultural Systems, 159, 1-8. https://doi.org/10.1016/j.agsy.2017.10.001

Commercial layer and indigenous chicken farming in Nairobi and associated activities in the egg value chains are a source of livelihood for urban families. A value chain mapping framework was used to describe types of inputs and outputs from chicken... Read More about Identification of production challenges and benefits using value chain mapping of egg food systems in Nairobi, Kenya.

Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae) (2018)
Journal Article
Michaels, C. J., Das, S., Chang, Y. M., & Tapley, B. (2018). Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae)

Aquatic predators must forage for prey in a complex three-dimensional environment where the availability of different prey types with different spatial niches may vary. Aquatic predators have evolved a number of ways in which they may respond to this... Read More about Modulation of foraging strategy in response to distinct prey items and their scents in the aquatic frog Xenopus longipes (Anura: Pipidae).

A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle (2018)
Journal Article
Meyer, A., Bond, K., Van Winden, S. C. L., Green, M., & Guitian, J. (2018). A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle. Preventive Veterinary Medicine, 150, 30-37. https://doi.org/10.1016/j.prevetmed.2017.11.016

Johne’s disease is a serious wasting disease of ruminants that is of high economic importance for the dairy sector in particular. The chronic nature of the disease, the fluctuations in antibody levels and the limited ability of diagnostic tests to id... Read More about A probabilistic approach to the interpretation of milk antibody results for diagnosis of Johne’s disease in dairy cattle.

Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-beta oligomers (2018)
Journal Article
McHale-Owen, H., & Bate, C. (2018). Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-beta oligomers. https://doi.org/10.1016/j.bbadis.2017.12.017

The production of amyloid-β (Aβ) is the key factor driving pathogenesis in Alzheimer's disease (AD). Increasing concentrations of Aβ within the brain cause synapse degeneration and the dementia that is characteristic of AD. Here the factors that affe... Read More about Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-beta oligomers.