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The specificity of phage testing for MAP — where might it fit into the diagnostic armoury? (2019)
Journal Article
Swift, B. M. C., & Rees, C. E. D. (2019). The specificity of phage testing for MAP — where might it fit into the diagnostic armoury?. Livestock, 24(4), https://doi.org/10.12968/live.2019.24.4.176

The current individual tools available for the diagnosis of Johne's disease are far from suitable to tackle this endemic disease. Culture, polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) tests, when used together can be... Read More about The specificity of phage testing for MAP — where might it fit into the diagnostic armoury?.

Searching for the source of Ebola: the elusive factors driving its spillover into humans during the West African outbreak of 2013–2016 (2019)
Book Chapter
Kock, R. A., Begovoeva, M., Ansumana, R., & Suluku, R. (2019). Searching for the source of Ebola: the elusive factors driving its spillover into humans during the West African outbreak of 2013–2016. . https://doi.org/10.20506/rst.issue.38.1.2937

The natural ecology of Ebola virus infection remains enigmatic. No clear reservoir species has been confirmed but there is evidence of infection in a wide spectrum of mammals, including humans, non-human primates, domestic and wild ungulates and a va... Read More about Searching for the source of Ebola: the elusive factors driving its spillover into humans during the West African outbreak of 2013–2016.

Energy turnover in mammalian skeletal muscle in contractions mimicking locomotion: effects of stimulus pattern on work, impulse and energetic cost and efficiency (2019)
Journal Article
Curtin, N. A., Woledge, R. C., West, T. G., Goodwin, D., Piercy, R. J., & Wilson, A. M. (2019). Energy turnover in mammalian skeletal muscle in contractions mimicking locomotion: effects of stimulus pattern on work, impulse and energetic cost and efficiency. Journal of Experimental Biology, 222, https://doi.org/10.1242/jeb.203877

Active muscle performs various mechanical functions during locomotion: work output during shortening, work absorption when resisting (but not preventing) lengthening, and impulse (force–time integral) whenever there is active force. The energetic cos... Read More about Energy turnover in mammalian skeletal muscle in contractions mimicking locomotion: effects of stimulus pattern on work, impulse and energetic cost and efficiency.

What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy? (2019)
Journal Article
Wells, D. J. (2019). What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?. Journal of Muscle Research and Cell Motility, 40(2), 141-150. https://doi.org/10.1007/s10974-019-09535-9

Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle wasting disease. The disease is due to mutations in the DMD gene that encodes for a large intracellular protein called dystrophin. Dystrophin plays a critical role in linking the internal c... Read More about What is the level of dystrophin expression required for effective therapy of Duchenne muscular dystrophy?.

Neurophysiological correlates of stereotypic behaviour in a model carnivore species (2019)
Journal Article
Diez-Leon, M., Kitchenham, L., Duprey, R., Bailey, C. D. C., Choleris, E., Lewis, M., & Mason, G. (2019). Neurophysiological correlates of stereotypic behaviour in a model carnivore species. Behavioural Brain Research, 373, https://doi.org/10.1016/j.bbr.2019.112056

Stereotypic behaviour (SB) is common in animals housed in farm, zoo or laboratory conditions, including captive Carnivora (e.g. wild ursids and felids). Neurobiological data on housing-induced SBs come from four species (macaques, two rodent species,... Read More about Neurophysiological correlates of stereotypic behaviour in a model carnivore species.

Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial (2019)
Journal Article
Sanchis-Mora, S., Chang, Y. M., Abeyesinghe, S. M., Fisher, A., Upton, N., Volk, H. A., & Pelligand, L. (2019). Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial. https://doi.org/10.1016/j.tvjl.2019.06.006

Pregabalin is the first-line treatment for neuropathic pain (NeP) in humans. Dogs with Chiari-like malformation and syringomyelia (CM/SM) associated with NeP could benefit from pregabalin. The aim of this study was to evaluate the efficacy of pregaba... Read More about Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial.

Comparison of the effects of high and low milk-replacer feeding regimens on health and growth of crossbred dairy heifers (2019)
Journal Article
Johnson, K. F., Vinod Nair, R., & Wathes, D. C. (2019). Comparison of the effects of high and low milk-replacer feeding regimens on health and growth of crossbred dairy heifers. Animal Production Science, https://doi.org/10.1071/AN18432

This study compared performance relating to the growth and health of calves receiving one of two commercial feeding regimens: High or Low.

Regulation of the bone vascular network is sexually dimorphic (2019)
Journal Article
Goring, A., Sharma, A., Javaheri, B., Smith, R. C., Kanczler, J. M., Boyde, A., Hesse, E., Mahajan, S., Olsen, B. R., Pitsillides, A. A., Schneider, P., Oreffo, R. O., & Clarkin, C. E. (2019). Regulation of the bone vascular network is sexually dimorphic. Journal of Bone and Mineral Research, https://doi.org/10.1002/jbmr.3825

Osteoblast (OB) lineage cells are an important source of vascular endothelial growth factor (VEGF), which is critical for bone growth and repair. During bone development, pubertal differences in males and females exist, but little is known about whet... Read More about Regulation of the bone vascular network is sexually dimorphic.

Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy (2019)
Journal Article
Swaffield, M., Hedley, J., Stapleton, N., Priestnall, S. L., Suárez-Bonnet, A., & Baldrey, V. (2019). Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy. Journal of Exotic Pet Medicine, https://doi.org/10.1053/j.jepm.2019.05.003

A six-month-old male entire ferret presented for investigation of atraumatic bilateral pelvic limb lameness. Radiographic and subsequent histopathological assessment of the femoral heads following bilateral femoral head ostectomy was consistent with... Read More about Bilateral capital physeal dysplasia in a ferret (Mustela putorius furo) treated with femoral head ostectomy.

Canine Ependymoma: Diagnostic Criteria and Common Pitfalls (2019)
Journal Article
Miller, A. D., Koehler, J. W., Donovan, T. A., Stewart, J. E., Porter, B. F., Rissi, D. R., Priestnall, S. L., & Schulman, F. Y. (2019). Canine Ependymoma: Diagnostic Criteria and Common Pitfalls. Veterinary Pathology, 56(6), 860-867. https://doi.org/10.1177/0300985819859872

Reports of canine ependymoma are generally restricted to single case reports with tumor incidence estimated at 2% to 3% of primary central nervous system (CNS) tumors. While most commonly reported in the lateral ventricle, tumors can occur anywhere i... Read More about Canine Ependymoma: Diagnostic Criteria and Common Pitfalls.

Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs (2019)
Journal Article
Pelander, L., Brunchault, V., Buffin-Meyer, B., Klein, J., Breuil, B., Zürbig, P., Magalhães, P., Mullen, W., Elliott, J., Syme, H. M., Schanstra, J. P., Häggström, J., & Ljungvall, I. (2019). Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs. https://doi.org/10.1016/j.tvjl.2019.05.010

Chronic kidney disease (CKD) is clinically important in canine medicine. Current diagnostic tools lack sensitivity for detection of subclinical CKD. The aim of the present study was to evaluate urinary peptidome analysis for diagnosis of CKD in dogs.... Read More about Urinary peptidome analyses for the diagnosis of chronic kidney disease in dogs.

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts (2019)
Journal Article
Patel, J. J., Bourne, L. E., Davies, B. K., Arnett, T. R., MacRae, V. E., Wheeler-Jones, C. P. D., & Orriss, I. R. (2019). Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts. Experimental Cell Research, 380(1), 100-113. https://doi.org/10.1016/j.yexcr.2019.04.020

Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, in the medial layer of the arteries. AMC shares some similarities to skeletal mineralisation and has been associated with the transdifferenti... Read More about Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts.

Sedative and antinociceptive effects of different detomidine constant rate infusions, with or without methadone in standing horses (2019)
Journal Article
Gozalo-Marcilla, M., Rodrigues De Oliveira, A., Werneck Fonseca, M., Possebon, F. S., Pelligand, L., Taylor, P. M., & Luna, S. P. L. (2019). Sedative and antinociceptive effects of different detomidine constant rate infusions, with or without methadone in standing horses. Equine Veterinary Journal, 51(4), 530-536. https://doi.org/10.1111/evj.13054

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases (2019)
Journal Article
Singhania, A., Graham, C. M., Gabryšová, L., Moreira-Teixeira, L., Stavropoulos, E., Pitt, J. M., Chakravarty, P., Warnatsch, A., Branchett, W. J., Conejero, L., Lin, J.-W., Davidson, S., Wilson, M. S., Bancroft, G., Langhorne, J., Frickel, E., Sesay, A. K., Priestnall, S. L., Herbert, E., Ioannou, M., …O’Garra, A. (2019). Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. Nature Communications, 10, https://doi.org/10.1038/s41467-019-10601-6

Understanding how immune challenges elicit different responses is critical for diagnosing and deciphering immune regulation. Using a modular strategy to interpret the complex transcriptional host response in mouse models of infection and inflammation... Read More about Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.

Clinical reasoning in feline spinal disease: which combination of clinical information is useful? (2019)
Journal Article
Mella, S. L., Cardy, T. J. A., Volk, H. A., & De Decker, S. (2019). Clinical reasoning in feline spinal disease: which combination of clinical information is useful?. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612X19858447

The aim of this study was to evaluate if a combination of discrete clinical characteristics can be used to identify the most likely differential diagnoses in cats with spinal disease.

Managed trade: The US–Mexico sugar suspension agreements (2019)
Journal Article
Carter, C. A., Saitone, T. L., & Schaefer, K. A. (2019). Managed trade: The US–Mexico sugar suspension agreements. Canadian Journal of Economics, https://doi.org/10.1111/caje.12393

Under the 1994 North American Free Trade Agreement, Mexican sugar producers were ultimately granted free access to the US sugar market, while all other suppliers, including US refiners, were subject to supply quotas. Following a surge in imports of M... Read More about Managed trade: The US–Mexico sugar suspension agreements.

Pet owners' awareness of animal blood banks and their motivations towards animal blood donation (2019)
Journal Article
Wilder, A., & Humm, K. R. (2019). Pet owners' awareness of animal blood banks and their motivations towards animal blood donation. Veterinary Record, https://doi.org/10.1136/vr.105139

The general public’s awareness of, and attitude to, canine and feline blood donation is poorly understood. Increasing understanding of pet owners’ thoughts about donation may allow more effective blood donor recruitment. The aims of this study were t... Read More about Pet owners' awareness of animal blood banks and their motivations towards animal blood donation.

Physics of Animal Health: On the mechano-biology of hoof growth and form (2019)
Journal Article
Al-Agele, R., Paul, E., Taylor, S., Watson, C., Sturrock, C., Drakopoulos, M., Atwood, R. C., Rutland, C. S., Menzies-Gow, N. J., Knowles, E., Elliott, J., Harris, P., & Rauch, C. (2019). Physics of Animal Health: On the mechano-biology of hoof growth and form. https://doi.org/10.1098/rsif.2019.0214

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of Animal Health: On the mechano-biology of hoof growth and form.

Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales (2019)
Journal Article
Wileman, T. M., Weinert, L. A., Howell, K. J., Wang, J., Peters, S. E., Williamson, S. M., Wells, J. M., Langford, P. R., Rycroft, A. N., Wren, B. W., Maskell, D. J., & Tucker, A. W. (2019). Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales. Journal of Clinical Microbiology, 57, e01712. https://doi.org/10.1128/JCM.01712-18

Streptococcus suis is one of the most important zoonotic bacterial pathogens of pigs, causing significant economic losses to the global swine industry. S. suis is also a very successful colonizer of mucosal surfaces, and commensal strains can be foun... Read More about Pathotyping the Zoonotic Pathogen Streptococcus suis: Novel Genetic Markers To Differentiate Invasive Disease-Associated Isolates from Non-Disease-Associated Isolates from England and Wales.