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Pulmonary mass-like lesion caused by Toxoplasma gondii in a domestic shorthair cat (2021)
Journal Article
McKenna, M., Augusto, M., Suarez-Bonnet, A., & Fitzgerald, E. (2021). Pulmonary mass-like lesion caused by Toxoplasma gondii in a domestic shorthair cat. Journal of Veterinary Internal Medicine, 35(3), 1547-1550. https://doi.org/10.1111/jvim.16111

A 2-year-old male neutered domestic shorthair cat underwent investigations for acute onset of lethargy, hyporexia, and cough. Computed tomography of the thorax identified a large mass-like lesion in the left cranial lung lobe and bilateral pleural ef... Read More about Pulmonary mass-like lesion caused by Toxoplasma gondii in a domestic shorthair cat.

Combined effect of probiotics and specific immunoglobulin Y directed against Escherichia coli on growth performance, diarrhea incidence, and immune system in calves (2021)
Journal Article
Karamzadeh-Dehaghani, A., Towhidi, A., Zhandi, M., Mojgani, N., & Fouladi-Nashta, A. (2021). Combined effect of probiotics and specific immunoglobulin Y directed against Escherichia coli on growth performance, diarrhea incidence, and immune system in calves. animal, 15(2), https://doi.org/10.1016/j.animal.2020.100124

Enterotoxigenic Escherichia coli (ETEC) K99 is one of the major pathogens associated with calf diarrhea. The induction of passive immunity in animals by immunoglobulin Y and using probiotics are inexpensive alternatives to antibiotics for the prevent... Read More about Combined effect of probiotics and specific immunoglobulin Y directed against Escherichia coli on growth performance, diarrhea incidence, and immune system in calves.

Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease (2021)
Journal Article
Gonzalez-Medina, S., Bevin, W., Alzola-Domingo, R., Chang, Y., & Piercy, R. (2021). Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease. Journal of Veterinary Internal Medicine, 35(2), 1170-1176. https://doi.org/10.1111/jvim.16077

Background Hypoglycin A (HGA) intoxication after ingestion of Acer spp. tree material has never been confirmed in domesticated ruminants despite their similar grazing habitats. Objectives To investigate whether sheep have low HGA bioavailability caus... Read More about Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease.

Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria (2021)
Journal Article
Nzelu, I., Kwaga, J., Kabir, J., Lawal, I., Beazley, C., Evans, L., & Blake, D. (2021). Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria. PLoS Neglected Tropical Diseases, 15(6), https://doi.org/10.1371/journal.pntd.0009458

Toxoplasma gondii parasites present strong but geographically varied signatures of population structure. Populations sampled from Europe and North America have commonly been defined by over-representation of a small number of clonal types, in contras... Read More about Detection and genetic characterisation of Toxoplasma gondii circulating in free-range chickens, pigs and seropositive pregnant women in Benue state, Nigeria.

Parasitological findings in the invasive California kingsnake (Lampropeltis californiae) in Gran Canaria, Spain (2021)
Journal Article
Santana-Hernandez, K., Oros, J., Priestnall, S., Monzon-Arguello, C., & Rodriguez-Ponce, E. (2021). Parasitological findings in the invasive California kingsnake (Lampropeltis californiae) in Gran Canaria, Spain. Parasitology, 148(11), 1345-1352. https://doi.org/10.1017/S0031182021000871

The California kingsnake (Lampropeltis californiae), native to North America, is a significant threat to the conservation of endemic species in the Spanish Macaronesian island of Gran Canaria. However, its role disseminating potential invasive parasi... Read More about Parasitological findings in the invasive California kingsnake (Lampropeltis californiae) in Gran Canaria, Spain.

Characterization and Antimicrobial Resistance of Environmental and Clinical Aeromonas Species Isolated from Fresh Water Ornamental Fish and Associated Farming Environment in Sri Lanka (2021)
Journal Article
Dhanapala, P., Kalupahana, R., Kalupahana, A., Wijesekera, D., Kottawatta, S., Jayasekera, N., …Jagoda, S. (2021). Characterization and Antimicrobial Resistance of Environmental and Clinical Aeromonas Species Isolated from Fresh Water Ornamental Fish and Associated Farming Environment in Sri Lanka. Microorganisms, 9(10), https://doi.org/10.3390/microorganisms9102106

The aims of this study were to characterize and investigate antimicrobial susceptibility and presence of integrons in 161 Aeromonas spp. isolated from ornamental freshwater fish farming environment, apparently healthy and diseased fish. Phylogenetic... Read More about Characterization and Antimicrobial Resistance of Environmental and Clinical Aeromonas Species Isolated from Fresh Water Ornamental Fish and Associated Farming Environment in Sri Lanka.

Effect of Speed and Surface Type on Individual Rein and Combined Left-Right Circle Movement Asymmetry in Horses on the Lunge (2021)
Journal Article
Pfau, T., Persson-Sjodin, E., Gardner, H., Orssten, O., Hernlund, E., & Rhodin, M. (2021). Effect of Speed and Surface Type on Individual Rein and Combined Left-Right Circle Movement Asymmetry in Horses on the Lunge. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.692031

Differences in movement asymmetry between surfaces and with increasing speed increase the complexity of incorporating gait analysis measurements from lunging into clinical decision making. This observational study sets out to quantify by means of qua... Read More about Effect of Speed and Surface Type on Individual Rein and Combined Left-Right Circle Movement Asymmetry in Horses on the Lunge.

Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance (2021)
Journal Article
Eilers, W., Cleasby, M., & Foster, K. (2021). Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-81222-7

Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle disorders and type 2 diabetes. However, there is currently no clinically effective myostatin inhibitor, and therefore nove... Read More about Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance.

The effect of myxomatous mitral valve disease severity on packed cell volume in dogs (2021)
Journal Article
Wilshaw, J., Stein, M., Lotter, N., Elliott, J., & Boswood, A. (2021). The effect of myxomatous mitral valve disease severity on packed cell volume in dogs. Journal of Small Animal Practice, 62(6), 428-436. https://doi.org/10.1111/jsap.13308

Objectives The aim of this study was to examine whether associations between disease severity and packed cell volume exist in dogs with myxomatous mitral valve disease. Materials and Methods Data were selected from 289 dogs that had been examined at... Read More about The effect of myxomatous mitral valve disease severity on packed cell volume in dogs.

Human-relevant near-organ neuromodulation of the immune via the nerve (2021)
Journal Article
Donega, M., Fjordbakk, C., Kirk, J., Sokal, D., Gupta, I., Hunsberger, G., …Perkins, J. (2021). Human-relevant near-organ neuromodulation of the immune via the nerve. Proceedings of the National Academy of Sciences, 118(20), https://doi.org/10.1073/pnas.2025428118

Neuromodulation of immune function by stimulating the autonomic connections to the spleen has been demonstrated in rodent models. Consequently, neuroimmune modulation has been proposed as a new therapeutic strategy for the treatment of inflammatory c... Read More about Human-relevant near-organ neuromodulation of the immune via the nerve.

Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time (2021)
Journal Article
Witkowska-Wrobel, A., Aristovich, K., Crawford, A., Perkins, J., & Holder, D. (2021). Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time. NeuroImage, 234, https://doi.org/10.1016/j.neuroimage.2021.117972

A B S T R A C T Intracranial EEG is the current gold standard technique for localizing seizures for surgery, but it can be insen-sitive to tangential dipole or distant sources. Electrical Impedance Tomography (EIT) offers a novel method to improve co... Read More about Imaging of focal seizures with Electrical Impedance Tomography and depth electrodes in real time.

Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii) (2021)
Journal Article
Fountain, K., Gibbon, M., Loeffler, A., & Feil, E. (2021). Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii). International Journal of Systematic and Evolutionary Microbiology, 71(3), https://doi.org/10.1099/ijsem.0.004715

The increasing availability of whole genome sequencing of bacteria has accelerated the discovery of novel species which may not have been easy to discriminate using standard phenotypic or single gene methods. Phylogenomic analysis of genome sequences... Read More about Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii).

The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression (2021)
Journal Article
McDonnell, C., Dunphy-Doherty, F., Rouine, J., Bianchi, M., Upton, N., Sokolowska, E., & Prenderville, J. (2021). The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression. Frontiers in Psychiatry, 11, https://doi.org/10.3389/fpsyt.2020.599588

Major depressive disorder (MDD) is the leading cause of disability worldwide. The majority of antidepressant drugs require several weeks or months of treatment to demonstrate efficacy and a subset of patients are resistant to such interventions. Keta... Read More about The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression.

Fracture-induced pain-like behaviours in a femoral fracture mouse model (2021)
Journal Article
Magnusdottir, R., Gohin, S., ter Heegde, F., Hopkinson, M., McNally, I., Fisher, A., …Chenu, C. (2021). Fracture-induced pain-like behaviours in a femoral fracture mouse model. Osteoporosis International, 32(11), 2347-2359. https://doi.org/10.1007/s00198-021-05991-7

This study is the first comprehensive characterisation of the pain phenotype after fracture using both evoked and naturalistic behaviours in adult male and ovariectomised female mice. It also shows that an anti-nerve growth factor (NGF) therapy could... Read More about Fracture-induced pain-like behaviours in a femoral fracture mouse model.

COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION (2021)
Journal Article
Perez, S., Encinoso, M., Morales, M., Arencibia, A., Suarez-Bonnet, A., Gonzalez-Rodriguez, E., & RaduanJaber, J. (2021). COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION. Slovenian Veterinary Research, 58(3), 111-116. https://doi.org/10.26873/SVR-1330-2021

The purpose of this paper was to do a comparative evaluation of the skull of two species of lizards, the Komodo dragon (Varanus komodoensis) and the Green Iguana ( Iguana iguana), by three-dimensional computed tomographic reconstruction. Images provi... Read More about COMPARATIVE EVALUATION OF THE KOMODO DRAGON (Varanus komodoensis) AND THE GREEN IGUANA (Iguana iguana) SKULL BY THREE-DIMENSIONAL COMPUTED TOMOGRAPHIC RECONSTRUCTION.

Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection (2021)
Journal Article
Al-Neama, R., Bown, K., Blake, D., & Birtles, R. (2021). Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection. Parasitology, 148(5), 623-629. https://doi.org/10.1017/S0031182021000044

Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enter... Read More about Determinants of Eimeria and Campylobacter infection dynamics in UK domestic sheep: the role of co-infection.

Defining a safe corridor for trans-iliac pin placement in cats (2021)
Journal Article
Garcia-Pertierra, S., Meeson, R., Yeung, B., Bedford, G., & Pead, M. (2021). Defining a safe corridor for trans-iliac pin placement in cats. Australian Veterinary Journal, 99(6), 242-248. https://doi.org/10.1111/avj.13062

Objective To identify whether a theoretical predictable safe corridor is available in cats for placement of trans-iliac pins without the use of fluoroscopy. Methods Twenty-one cats with straight orthogonal normal pelvic radiographs were included. Two... Read More about Defining a safe corridor for trans-iliac pin placement in cats.

Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice (2021)
Journal Article
Galea, G., Maniou, E., Edwards, T., Marshall, A., Ampartzidis, I., Greene, N., & Copp, A. (2021). Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice. Nature Communications, 12(1), https://doi.org/10.1038/s41467-021-21372-4

Post-zygotic mutations that generate tissue mosaicism are increasingly associated with severe congenital defects, including those arising from failed neural tube closure. Here we report that neural fold elevation during mouse spinal neurulation is vu... Read More about Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice.

Comparison of the Ability of High and Low Virulence Strains of Non-cytopathic Bovine Viral Diarrhea Virus-1 to Modulate Expression of Interferon Tau Stimulated Genes in Bovine Endometrium (2021)
Journal Article
Wang, K., Thomas, C., Zhang, S., Wathes, D., & Cheng, Z. (2021). Comparison of the Ability of High and Low Virulence Strains of Non-cytopathic Bovine Viral Diarrhea Virus-1 to Modulate Expression of Interferon Tau Stimulated Genes in Bovine Endometrium. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.659330

Bovine Viral Diarrhea virus (BVDV) is a pestivirus with a single-stranded, positive sense RNA genome. It is endemic in many cattle populations, causing major economic losses in part due to reduced fertility. BVDV exhibits great genetic diversity and... Read More about Comparison of the Ability of High and Low Virulence Strains of Non-cytopathic Bovine Viral Diarrhea Virus-1 to Modulate Expression of Interferon Tau Stimulated Genes in Bovine Endometrium.

The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia (2021)
Journal Article
Rebecca, F., van den Broek, D., Chang, Y., Biourge, V., Elliott, J., & Jepson, R. (2021). The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia. Journal of Veterinary Internal Medicine, 35(2), 997-1007. https://doi.org/10.1111/jvim.16050

Background Hypercalcemia is commonly observed in cats with azotemic chronic kidney disease (CKD). Dietary phosphate restriction is considered standard of care but may contribute to the development of hypercalcemia. The optimal dietary management stra... Read More about The effect of attenuating dietary phosphate restriction on blood ionized calcium concentrations in cats with chronic kidney disease and ionized hypercalcemia.