Skip to main content

Research Repository

Advanced Search

All Outputs (506)

Probing differences in gene essentiality between the human and animal adapted (2021)
Journal Article
Gibson, A. J., Passmore, I. J., Faulkner, V., Xia, D., Nobeli, I., Stiens, J., …Kendall, S. L. (2021). Probing differences in gene essentiality between the human and animal adapted. Frontiers in Veterinary Science,

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, ho... Read More about Probing differences in gene essentiality between the human and animal adapted.

First reported case of fragile foal syndrome type 1 in the Thoroughbred caused by PLOD1 c.2032G>A (2021)
Journal Article
Grillos, A., Roach, J., de Mestre, A., Foote, A., Kinglsey, N., Mienaltowski, M., & Bellone, R. (in press). First reported case of fragile foal syndrome type 1 in the Thoroughbred caused by PLOD1 c.2032G>A. Equine Veterinary Journal, https://doi.org/10.1111/evj.13547

Background Warmblood Fragile Foal Syndrome Type 1 (WFFS) is an autosomal recessive disorder reported previously only in warmbloods and thought to be caused by a variant in the gene procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1, c.2032G>A,... Read More about First reported case of fragile foal syndrome type 1 in the Thoroughbred caused by PLOD1 c.2032G>A.

Vesicular dysfunction and pathways to neurodegeneration (2021)
Journal Article
Lewis, P. (2021). Vesicular dysfunction and pathways to neurodegeneration. Essays in Biochemistry, 65(7), 941-948. https://doi.org/10.1042/ebc20210034

Cellular control of vesicle biology and trafficking is critical for cell viability, with disruption of these pathways within the cells of the central nervous system resulting in neurodegeneration and disease. The past two decades have provided import... Read More about Vesicular dysfunction and pathways to neurodegeneration.

Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England (2021)
Journal Article
Romero, M. P., Chang, Y., Brunton, L. A., Parry, J., Prosser, A., Upton, P., & Drewe, J. A. (2021). Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England. Preventive Veterinary Medicine,

Bovine tuberculosis (bTB) remains one of the most complex, challenging, and costly animal health problems in England. Identifying and promptly removing all infected cattle from affected herds is key to its eradication strategy; the imperfect sensitiv... Read More about Machine learning classification methods informing the management of inconclusive reactors at bovine tuberculosis surveillance tests in England.

Phylogenetic Analysis of H5N8 Highly Pathogenic Avian Influenza Viruses in Ukraine, 2016-2017 (2021)
Journal Article
Sapachova, M., Kovalenko, G., Sushko, M., Bezymennyi, M., Muzyka, D., Usachenko, N., …Bortz, E. (2021). Phylogenetic Analysis of H5N8 Highly Pathogenic Avian Influenza Viruses in Ukraine, 2016-2017. Vector-Borne and Zoonotic Diseases, 21(12), 979-988. https://doi.org/10.1089/vbz.2021.0031

Highly pathogenic avian influenza viruses (HPAIV) can be carried long distances by migratory wild birds and by poultry trade. Highly pathogenic avian influenza (HPAI) is often lethal in domestic poultry and can sporadically infect and cause severe re... Read More about Phylogenetic Analysis of H5N8 Highly Pathogenic Avian Influenza Viruses in Ukraine, 2016-2017.

A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia (2021)
Journal Article
GOSgene, Whittaker, D., Oleari, R., Gregory, L., Le Quesne-Stabej, P., Williams, H., …Dattani, M. (2021). A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. Journal of Clinical Investigation, 131(24), https://doi.org/10.1172/JCI141587

The positive regulatory (PR) domain containing 13 (PRDM13) putative chromatin modifier and transcriptional regulator functions downstream of the transcription factor PTF1A, which controls GABAergic fate in the spinal cord and neurogenesis in the hypo... Read More about A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia.

Computed tomographic findings and clinical features in dogs with canine cutaneous lymphoma: 10 cases (2007-2018) (2021)
Journal Article
Watton, T., Purzycka, K., & Fitzgerald, E. (2021). Computed tomographic findings and clinical features in dogs with canine cutaneous lymphoma: 10 cases (2007-2018). Journal of the American Veterinary Medical Association, 259(12), 1433-1440. https://doi.org/10.2460/javma.20.11.0635

OBJECTIVE To report clinical features, CT findings, treatment protocols, and outcomes for dogs in which canine cutaneous lymphoma (CCL) was diagnosed. ANIMALS 10 client -owned dogs with CCL. PROCEDURES Medical records of dogs in which a diagnosis of... Read More about Computed tomographic findings and clinical features in dogs with canine cutaneous lymphoma: 10 cases (2007-2018).

Leveraging Sub-national Collaboration and Influence for Improving Animal Health Surveillance and Response: A Stakeholder Mapping in Tanzania (2021)
Journal Article
George, J., Häsler, B., Komba, E. V. G., Sindato, C., Rweyemamu, M., Kimera, S. I., & Mlangwa, J. E. D. (in press). Leveraging Sub-national Collaboration and Influence for Improving Animal Health Surveillance and Response: A Stakeholder Mapping in Tanzania. Frontiers in Veterinary Science, 8, https://doi.org/10.3389/fvets.2021.738888

Animal health surveillance plays a vital role in ensuring public health, animal welfare, and sustainable food production by monitoring disease trends, early detecting (new) hazards, facilitating disease control and infection, and providing data for r... Read More about Leveraging Sub-national Collaboration and Influence for Improving Animal Health Surveillance and Response: A Stakeholder Mapping in Tanzania.

Primary orthostatic tremor and orthostatic tremor plus in dogs: 60 cases (2003 - 2020) (2021)
Journal Article
Liatis, T., Gutierrez-Quintana, R., Mari, L., Czopowicz, M., Polidoro, D., Bhatti, S. F., …Rossmeisl, J. H. (in press). Primary orthostatic tremor and orthostatic tremor plus in dogs: 60 cases (2003 - 2020). Journal of Veterinary Internal Medicine,

Background: Orthostatic tremor (OT) is a rare movement disorder characterized by high- frequency (>12 Hz) involuntary, rhythmic, sinusoidal movements affecting predominantly the limbs while standing. Objective: To describe the signalment, presenti... Read More about Primary orthostatic tremor and orthostatic tremor plus in dogs: 60 cases (2003 - 2020).

Community engagement: The key to tackling Antimicrobial Resistance (AMR) across a One Health context? (2021)
Journal Article
Mitchell, J., Cooke, P., Ahorlu, C., Arjyal, A., Baral, S., Carter, L., …King, R. (2022). Community engagement: The key to tackling Antimicrobial Resistance (AMR) across a One Health context?. Global Public Health, 17(11), 2647-2664. https://doi.org/10.1080/17441692.2021.2003839

Antimicrobial resistance (AMR) is a One Health problem underpinned by complex drivers and behaviours. This is particularly so in low - and middle-income countries (LMICs), where social and systemic factors fuel (mis)use and drive AMR. Behavioural cha... Read More about Community engagement: The key to tackling Antimicrobial Resistance (AMR) across a One Health context?.

Renal Senescence, Telomere Shortening and Nitrosative Stress in Feline Chronic Kidney Disease (2021)
Journal Article
Quimby, J., Erickson, A., Mcleland, S., Cianciolo, R., Maranon, D., Lunn, K., …Bailey, S. (2021). Renal Senescence, Telomere Shortening and Nitrosative Stress in Feline Chronic Kidney Disease. Veterinary Sciences, 8(12), https://doi.org/10.3390/vetsci8120314

Kidney tissues from cats with naturally occurring chronic kidney disease (CKD) and adult and senior cats without CKD were assessed to determine whether telomere shortening and nitrosative stress are associated with senescence in feline CKD. The histo... Read More about Renal Senescence, Telomere Shortening and Nitrosative Stress in Feline Chronic Kidney Disease.