Skip to main content

Research Repository

Advanced Search

All Outputs (412)

Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension (2022)
Journal Article
Al Hosni, R., Bozec, L., Roberts, S. J., & Cheema, U. (2022). Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension. iScience, 25(4), 104059. https://doi.org/10.1016/j.isci.2022.104059

The biophysical microenvironment of the cell is being increasingly used to control cell signaling and to direct cell function. Herein, engineered 3D tuneable biomimetic scaffolds are used to control the cell microenvironment of Adipose-derived Mesenc... Read More about Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension.

Feline Femoral Fracture Fixation: What are the options? (2022)
Journal Article
Roberts, V. J., & Meeson, R. L. (in press). Feline Femoral Fracture Fixation: What are the options?. Journal of Feline Medicine and Surgery, 1098612X2210903. https://doi.org/10.1177/1098612x221090391

Practical relevance: The femur is the most commonly fractured bone in cats. Femoral fractures usually result from high-velocity trauma such as a road traffic accident or fall from a height and, as such, are associated with a wide variety of concurren... Read More about Feline Femoral Fracture Fixation: What are the options?.

The immunomodulatory effects of statins on macrophages Author information (2022)
Journal Article
Sheridan, A., Wheeler-Jones, C., & Gage, M. C. (2022). The immunomodulatory effects of statins on macrophages Author information. Immuno, https://doi.org/10.3390/immuno2020021

Statins are extensively used in the medical practice, with their action as lipid-lowering agents proving to be central in the treatment of atherosclerotic cardiovascular disease. However, in addition to their cholesterol-reducing effects, mounting ev... Read More about The immunomodulatory effects of statins on macrophages Author information.

Chemical Characterization and Cytotoxic/Antibacterial Effects of Nine Iranian Propolis Extracts on Human Fibroblast Cells and Oral Bacteria (2022)
Journal Article
Yazdanian, M., Motallaei, M., Tahmasebi, E., Tebyaniyan, H., Alam, M., Abbasi, K., …Moghaddam, M. (2022). Chemical Characterization and Cytotoxic/Antibacterial Effects of Nine Iranian Propolis Extracts on Human Fibroblast Cells and Oral Bacteria. BioMed Research International, 2022, https://doi.org/10.1155/2022/6574997

Multimicrobial infections caused by pathobionts are called dysbiotic multimicrobial illnesses. Commercial mouthwashes, such as chlorhexidine, have negative side effects that can prevent tooth decay and infection. The present study aimed to determine... Read More about Chemical Characterization and Cytotoxic/Antibacterial Effects of Nine Iranian Propolis Extracts on Human Fibroblast Cells and Oral Bacteria.

Ocean Currents May Influence the Endolithic Bacterial Composition in Coral Skeletons (2022)
Journal Article
Liu, P., Yang, S., Lu, C., Wada, N., De Palmas, S., Yeh, S., …Yang, S. (2022). Ocean Currents May Influence the Endolithic Bacterial Composition in Coral Skeletons. Frontiers in Marine Science, 9, https://doi.org/10.3389/fmars.2022.850984

Coral endolithic microbes can be an important nutrients support for hosts while under stresses. Previous studies have found that the endolithic microbial composition of a single coral species can be biogeographical diverse. However, the potential env... Read More about Ocean Currents May Influence the Endolithic Bacterial Composition in Coral Skeletons.

Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals (2022)
Journal Article
Almeida, A., Soares-de-Oliveira, J., Drpic, D., Cheeseman, L., Damas, J., Lewin, H., …Maiato, H. (2022). Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals. Cell Reports, 39(1), https://doi.org/10.1016/j.celrep.2022.110610

Chromosome segregation in mammals relies on the maturation of a thick bundle of kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial kinetochore microtubule attachments remains a fundamental question. By combining mole... Read More about Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals.

The UK Antimicrobial Resistance Strategy 2013–18: A Qualitative Study of International and Domestic Policy and Action Related to Livestock and the Food Chain (2022)
Journal Article
Blake, L. J., Häsler, B., Bennani, H., Mateus, A. L. P., Eastmure, E., Mays, N., & Stärk, K. D. C. (2022). The UK Antimicrobial Resistance Strategy 2013–18: A Qualitative Study of International and Domestic Policy and Action Related to Livestock and the Food Chain. Frontiers in Sustainable Food Systems, 6, -. https://doi.org/10.3389/fsufs.2022.819158

Antimicrobial resistance (AMR) is an increasingly important challenge within global health, and growing action is being taken by countries across the world. The UK Government established a national AMR Strategy in 2013, encompassing human and animal... Read More about The UK Antimicrobial Resistance Strategy 2013–18: A Qualitative Study of International and Domestic Policy and Action Related to Livestock and the Food Chain.

Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure (2022)
Journal Article
Walker, A., DeFrancesco, T., Bonagura, J., Keene, B., Meurs, K., Tou, S., …Adin, D. (2022). Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure. Journal of Veterinary Cardiology, 40, 99-109. https://doi.org/10.1016/j.jvc.2021.02.001

Introduction: Dilated cardiomyopathy (DCM) in dogs has been associated with feeding of grain-free (GF), legume-rich diets. Some dogs with presumed diet-associated DCM have shown improved myocardial function and clinical outcomes following a change in... Read More about Association of diet with clinical outcomes in dogs with dilated cardiomyopathy and congestive heart failure.

Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus (2022)
Journal Article
Collings, A., Eberhard, E., Basu, C., & Richards, C. (2022). Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus. Frontiers in Bioengineering and Biotechnology, 10, https://doi.org/10.3389/fbioe.2022.806174

Using their abundant musculature, frogs are able to exhibit outstanding behavioural versatility. However, understanding the dynamic motion of their 30 + hindlimb muscles, with multi-joint action, and curved pathways, is challenging. This is particula... Read More about Functional Analysis of Anuran Pelvic and Thigh Anatomy Using Musculoskeletal Modelling of Phlyctimantis maculatus.

Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia–Ischemia (2022)
Journal Article
Nair, S., Leverin, A., Rocha-Ferreira, E., Sobotka, K., Thornton, C., Mallard, C., & Hagberg, H. (2022). Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia–Ischemia. Cells, https://doi.org/10.3390/cells11071193

Abstract: Hypoxia–ischemia (HI) leads to immature brain injury mediated by mitochondrial stress. If damaged mitochondria cannot be repaired, mitochondrial permeabilization ensues, leading to cell death. Non-optimal turnover of mitochondria is criti... Read More about Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia–Ischemia.

Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy (2022)
Journal Article
Bostrom, A., Parzefall, B., Blutke, A., & Davies, E. (2022). Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy. Research in Veterinary Science, 146, 60-69. https://doi.org/10.1016/j.rvsc.2022.03.011

Cross-sectional area (CSA) decreases and fat infiltration increases in epaxial muscles of Dachshunds with intervertebral disc disease (IVDD), but less is known about large breed dogs with IVDD. The aim here was to investigate thoracolumbar epaxial mu... Read More about Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy.