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All Outputs (402)

Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv (2022)
Journal Article
Asai, M., Li, Y., Spiropoulos, J., Cooley, W., Everest, D. J., Kendall, S., …Newton, S. M. (2022). Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv. Virulence, https://doi.org/10.1080/21505594.2022.2119657

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a leading cause of infectious disease mortality. Animal infection models have contributed substantially to our understanding of TB, yet their biological and non-biological limitation... Read More about Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv.

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins (2022)
Journal Article
Cogo, S., Tomkins, J., Vavouraki, N., Giusti, V., Forcellato, F., Franchin, C., …Greggio, E. (2022). Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins. Neurobiology of Disease, 174, https://doi.org/10.1016/j.nbd.2022.105858

Mutations in SPG11, encoding spatacsin, constitute the major cause of autosomal recessive Hereditary Spastic Paraplegia (HSP) with thinning of the corpus callosum. Previous studies showed that spatacsin orchestrates cellular traffic events through th... Read More about Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

Survey investigating factors affecting recruitment and retention in the UK veterinary nursing profession (2022)
Journal Article
Hagen, J., Weller, R., Mair, T., Batt-Williams, S., & Kinnison, T. (2022). Survey investigating factors affecting recruitment and retention in the UK veterinary nursing profession. Vet Record Case Reports, https://doi.org/10.1002/vetr.2078

Background: Recruitment and retention have been identified as contributing factors to workforce shortages in the veterinary team. Methods: Results from veterinary nurses to an online questionnaire regarding recruitment and retention were analysed. Re... Read More about Survey investigating factors affecting recruitment and retention in the UK veterinary nursing profession.

Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession (2022)
Journal Article
Hagen, J., Weller, R., Mair, T., Batt-Williams, S., & Kinnison, T. (2022). Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession. Vet Record Case Reports, https://doi.org/10.1136/vr.106044

Background Recruitment and retention have been identified as contributing factors to workforce shortages in the veterinary team. Methods In this second part of a project exploring recruitment and retention in veterinary professions, results from v... Read More about Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession.

Additional stains and immunohistochemistry: what else can the pathologist tell us? (2022)
Journal Article
Priestnall, S., & Suarez-Bonnet, A. (2022). Additional stains and immunohistochemistry: what else can the pathologist tell us?. In Practice, 44(7), 385-393. https://doi.org/10.1002/inpr.90

Background: For the veterinary pathologist, the 'bread and butter' of our work is the tissue slide stained with haematoxylin and eosin (H&E). This has long become globally recognised as the 'standard' stain, with haematoxylin highlighting the nuclei... Read More about Additional stains and immunohistochemistry: what else can the pathologist tell us?.

Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance (2022)
Journal Article
Díaz, A. V., Lambert, S., Neves, M. I., Borlase, A., Léger, E., Diouf, N. D., …Walker, M. (2022). Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance. Frontiers in Tropical Diseases, 3, 1-12. https://doi.org/10.3389/fitd.2022.893066

Schistosomiasis, a neglected tropical disease, is a widespread chronic helminthiasis reported in 78 countries, predominantly those within sub-Saharan Africa, as well as Latin America, Asia, and most recently, even Europe. Species of the causative blo... Read More about Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance.

Endogenous Viral Elements in Shrew Genomes Provide Insights into Pestivirus Ancient History (2022)
Journal Article
Li, Y., Bletsa, M., Zisi, Z., Boonen, I., Gryseels, S., Kafetzopoulou, L., …Lequime, S. (2022). Endogenous Viral Elements in Shrew Genomes Provide Insights into Pestivirus Ancient History. Molecular Biology and Evolution, 39(10), https://doi.org/10.1093/molbev/msac190

As viral genomic imprints in host genomes, endogenous viral elements (EVEs) shed light on the deep evolutionary history of viruses, ancestral host ranges, and ancient viral-host interactions. In addition, they may provide crucial information for cali... Read More about Endogenous Viral Elements in Shrew Genomes Provide Insights into Pestivirus Ancient History.

Copy Number Variants in Two Northernmost Cattle Breeds Are Related to Their Adaptive Phenotypes (2022)
Journal Article
Buggiotti, L., Yudin, N., & Larkin, D. (2022). Copy Number Variants in Two Northernmost Cattle Breeds Are Related to Their Adaptive Phenotypes. Genes, 13(9), https://doi.org/10.3390/genes13091595

Copy number variations (CNVs) are genomic structural variants with potential functional and evolutionary effects on phenotypes. In this study, we report the identification and characterization of CNVs from the whole-genome resequencing data of two no... Read More about Copy Number Variants in Two Northernmost Cattle Breeds Are Related to Their Adaptive Phenotypes.

Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma (2022)
Journal Article
Azzariti, S., Bond, R., Loeffler, A., Zendri, F., Timofte, D., Chang, Y., & Pelligand, L. (2022). Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma. Antibiotics, https://doi.org/10.3390/antibiotics11091204

Fluoroquinolones (FQ) are commonly used in dogs with bacterial skin infections. Their use as first choice, along with the increased incidence of FQ-resistance, represents a risk to animal and public health. Our study determined minimum inhibitory (M... Read More about Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma.

Computed tomographic arthrography, gross anatomy and histology demonstrate a communication between synovial invaginations in the proximal aspect of the third interosseous muscle and the carpometacarpal joint in horses (2022)
Journal Article
Gerdes, C., Morgan, R., Terry, R., Foote, A., & Smith, R. (2022). Computed tomographic arthrography, gross anatomy and histology demonstrate a communication between synovial invaginations in the proximal aspect of the third interosseous muscle and the carpometacarpal joint in horses. Frontiers in Veterinary Science, 9, https://doi.org/10.3389/fvets.2022.958598

This descriptive anatomical study investigates the relationship between the third interosseous muscle, also known as the suspensory ligament, and the carpometacarpal joint in forelimbs of horses, with the hypothesis that there was a direct synovial c... Read More about Computed tomographic arthrography, gross anatomy and histology demonstrate a communication between synovial invaginations in the proximal aspect of the third interosseous muscle and the carpometacarpal joint in horses.

Histopathological description of iridophoromas resembling skin nodule syndrome in Siamese fighting fish Betta splendens (2022)
Journal Article
Oros, J., Priestnall, S., & Suarez-Bonnet, A. (2022). Histopathological description of iridophoromas resembling skin nodule syndrome in Siamese fighting fish Betta splendens. Diseases of Aquatic Organisms, 151, 23-27. https://doi.org/10.3354/dao03686

Intensive breeding of the Siamese fighting fish Betta splendens, a species that inhabits marshlands in Thailand and other countries in south-east Asia, was traditionally focused on game fighting because the males are very territorial, but has evolved... Read More about Histopathological description of iridophoromas resembling skin nodule syndrome in Siamese fighting fish Betta splendens.

Spherical Frame Projections for Visualizing Joint Range of Motion (2022)
Journal Article
Herbst, E. C., Eberhard, E. A., Richards, C. T., & Hutchinson, J. R. (2022). Spherical Frame Projections for Visualizing Joint Range of Motion. Journal of Experimental Biology, https://doi.org/10.1242/jeb.xxxxxx

Quantifying joint range of motion (RoM), the reachable poses at a joint, has many applications in research and clinical care. Joint RoM measurements can be used to investigate the link between form and function in extant and extinct animals, to diagn... Read More about Spherical Frame Projections for Visualizing Joint Range of Motion.

Effect of tuberculin skin testing on serological results against Mycobacterium avium ssp. paratuberculosis (MAP): Evidence of distinct effects in MAP-infected and noninfected cows. (2022)
Journal Article
Nunney, E., Crotta, M., Van Winden, S., Bond, K., Green, M., & Guitian, J. (2022). Effect of tuberculin skin testing on serological results against Mycobacterium avium ssp. paratuberculosis (MAP): Evidence of distinct effects in MAP-infected and noninfected cows. Journal of Dairy Science, https://doi.org/10.3168/jds.2021-21753

Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves (2022)
Journal Article
Mead, A., Toutain, P., Richez, P., & Pelligand, L. (2022). Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves. Antimicrobial Agents and Chemotherapy, https://doi.org/10.1128/aac.00793-22

Heteroresistance correspond to the presence in a bacterial isolate of an initial small subpopulation of bacteria characterized by a significant reduction in their sensitivity to a given antibiotic. Mechanisms of heteroresistance vs. resistance are po... Read More about Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves.

Can AI imaging technology be used for monitoring specific behaviours in broiler flocks (2022)
Conference Proceeding
Demmers, T. (2022). Can AI imaging technology be used for monitoring specific behaviours in broiler flocks.

Commercial poultry production, e.g. optimum bird growth, requires an optimally controlled environment, which is currently based upon temperature, humidity, CO2 and air pressure, whilst water and feed consumption are also measured. PLF systems exist... Read More about Can AI imaging technology be used for monitoring specific behaviours in broiler flocks.