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Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences (2023)
Journal Article
Chang, Y., Xia, D., & Billows, N. (2023). Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences. Bioinformatics, 39(7), https://doi.org/10.1093/bioinformatics/btad428

Background: Tuberculosis is caused by members of the Mycobacterium tuberculosis complex (MTBC) and is the second leading infectious killer after COVID-19. The evolution of drug-resistance poses a threat to successful treatment and disease eradication... Read More about Feature Weighted Models (FWM) to address lineage dependency in drug-resistance prediction from Mycobacterium tuberculosis genome sequences.

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J., Amaral, A., …Pomba, C. (2023). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Extended-spectrum beta-lactamase (ESBL)- and plasmid-mediated cephalosporinase (AmpC)-producing Enterobacterales (ESBL/AmpC-E) are an increasing healthcare problem in both human and veterinary medicine. The aim of this study was to investigate the po... Read More about Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom.

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J. M., Amaral, A. J., …Pomba, C. (in press). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony (2023)
Journal Article
Veen, I., & de Grauw, J. (2023). Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony. Vet Record Case Reports, https://doi.org/10.1002/vrc2.670

A Shetland pony suspected of large intestinal displacement was presented for exploratory laparotomy. The pony was extremely agitated with refractory pain despite repeated intravenous administration of detomidine and morphine. As the pony became unman... Read More about Insufficient effect of sedation followed by difficulties inducing a colicking Shetland pony.

Repeat histopathology and culture of colonic biopsy specimens after treatment for Escherichia coli-associated granulomatous colitis in a cat (2023)
Journal Article
Waite, O., Yaffy, D., & Kathrani, A. (2023). Repeat histopathology and culture of colonic biopsy specimens after treatment for Escherichia coli-associated granulomatous colitis in a cat. Journal of Feline Medicine and Surgery Open Reports, 9(2), https://doi.org/10.1177/20551169231178442

Case summaryA 7.5-year-old neutered male Oriental Shorthair cat presented with an 8-month history of haematochezia, mucoid diarrhoea, tenesmus and vocalisation after a 4-year history of small bowel diarrhoea. Transabdominal ultrasonography confirmed... Read More about Repeat histopathology and culture of colonic biopsy specimens after treatment for Escherichia coli-associated granulomatous colitis in a cat.

Clinical presentation and outcome of gastric impactions with or without concurrent intestinal lesions in horses (2023)
Journal Article
Talbot, S., Tallon, R., & Dunkel, B. (2023). Clinical presentation and outcome of gastric impactions with or without concurrent intestinal lesions in horses. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16735

BackgroundGastric impactions (GI) have been identified as primary lesions (lone GI; LGI) or associated with other intestinal lesions (concurrent GI; CGI). Anecdotally, CGI resolve more rapidly with a better prognosis than LGI. ObjectivesTo determine... Read More about Clinical presentation and outcome of gastric impactions with or without concurrent intestinal lesions in horses.

Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524 (2023)
Journal Article
Green, J., Syme, H., & Tayler, S. (2023). Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16804

BackgroundGS-441524 has been successfully used to treat feline infectious peritonitis (FIP) in cats. However, the use of its prodrug, remdesivir, in combination with a PO GS-441524 containing product for the treatment of FIP has not yet been describe... Read More about Thirty-two cats with effusive or non-effusive feline infectious peritonitis treated with a combination of remdesivir and GS-441524.

Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021 (2023)
Journal Article
Brand, C., Packer, R., Brand, C., Belshaw, Z., Pegram, C., Dale, F., …O'Neill, D. (2023). Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021. Animals, 13(13), 2186. https://doi.org/10.3390/ani13132186

The COVID-19 pandemic led to a surge in acquisitions of puppies in the UK, dubbed the “Pandemic Puppy” phenomenon. In addition to an increased demand for puppies, widespread changes to both why and how puppies were purchased during this period compar... Read More about Is UK Puppy Purchasing Suffering a Long COVID Effect? Ongoing Negative Impacts of the COVID-19 Pandemic upon Puppy Purchase Motivations and Behaviours in 2021.

Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease (2023)
Journal Article
Oyama, M., Scansen, B., Boswood, A., Goldfeder, G., Rosenthal, S., Cober, R., …Li, Q. (2023). Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16796

BackgroundPrevious studies in dogs with degenerative mitral valve disease (DMVD) have identified altered myocardial energy metabolism and oxidation, which might contribute to cardiac hypertrophy. Diets rich in medium chain fatty acids and antioxidant... Read More about Effect of a specially formulated diet on progression of heart enlargement in dogs with subclinical degenerative mitral valve disease.

Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM (2023)
Journal Article
Beeston, D., & Cortellini, S. (in press). Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM. Veterinary Record,

This case report details the clinical investigation of an 11-month intact male Cockapoo who presented with acute left forebrain signs associated with suspected intra-cranial haemorrhage due to Angiostrongylus vasorum. Initial investigations faile... Read More about Demonstration of Angiostrongylus vasorum associated hyperfibrinolysis and its resolution following tranexamic acid on the VCM VetTM.

Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide (2023)
Journal Article
McNally, A., Rossanese, M., Suárez‐Bonnet, A., Hardas, A., & Yale, A. D. (in press). Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16750

Visceral hemangiosarcomas (HSA) are rare in cats and typically associated with aggressive biologic behavior and poor prognosis. A 4-year-old male neutered domestic shorthair cat was presented with a 3-month history of hematuria and stranguria; ultras... Read More about Urinary bladder hemangiosarcoma in a cat treated with partial cystectomy and adjuvant metronomic cyclophosphamide and thalidomide.

Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm (2023)
Journal Article
Mahendran, S., Blackie, N., Wathes, C., & booth, R. (2023). Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm. Animals, https://doi.org/10.3390/ani13132140

Social pair housing of calves has previously demonstrated positive impacts on calf health and productivity compared to individual housing, but much of the research has been conducted in research institutions in different environmental conditions to t... Read More about Effects of individual and pair housing of calves on short term health and behaviour on a UK commercial dairy farm.

Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics (2023)
Journal Article
Murray, R., Fisher, M., Fairfax, V., & MacKechnie-Guire, R. (2023). Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics. Animals, 13(13), https://doi.org/10.3390/ani13132127

Simple Summary There is increasing interest in the effect of saddle design on horse kinematics, but little evidence of the influence on rider-saddle interaction and how this affects horse movement patterns. We aimed to investigate the effect of chang... Read More about Saddle Thigh Block Design Can Influence Rider and Horse Biomechanics.

Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy (2023)
Journal Article
Cheng, W., Lawson, C., Liu, H., Wilkie, L., Dobromylskyj, M., Fuentes, V. L., …Connolly, D. J. (2023). Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy. Animals, 13(13), 2112. https://doi.org/10.3390/ani13132112

Simple Summary: The hallmark changes in hypertrophic cardiomyopathy (HCM), a naturally occurring heart disease in both humans and cats, are left ventricular hypertrophy (LVH) and myocardial fibrosis. Key myocardial proteins, lumican, lysyl oxidase (L... Read More about Exploration of Mediators Associated with Myocardial Remodelling in Feline Hypertrophic Cardiomyopathy.

Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study (2023)
Journal Article
Pelligand, L., Baker, D., Sivagurunathan, A., Kovačević, Z., Suemanotham, N., Stair, J. L., …Steagall, P. V. (in press). Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13648

Objectives: Antimicrobial formulations of substandard quality have negative consequences for efficacy in patients and potentially promote antimicrobial resistance. Amoxicillin/clavulanate (AMC) is the most commonly used oral antimicrobial drug in com... Read More about Are there substandard amoxicillin/clavulanic acid oral formulations for intended veterinary use in Malaysia, the United Kingdom, Serbia and Thailand? A convenience sampling study.

Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma (2023)
Journal Article
Williams, J., Werling, D., Davison, L., Hiron, T., & Xia, D. (in press). Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma. Journal of Comparative Pathology, https://doi.org/10.1016/j.jcpa.2023.03.186

Differentiating between canine inflammatory bowel disease and intestinal T-cell lymphoma via histopathological examination of endoscopically-derived intestinal biopsies can be challenging and involves an invasive procedure requiring specialised equip... Read More about Characterisation of Canine Intestinal MicroRNA Expression in Inflammatory Bowel Disease and T-Cell Lymphoma.