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Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication (2023)
Journal Article
Savagar, B., Jones, B. A., Arnold, M., Walker, M., & Fournié, G. (2023). Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication. Epidemics, 45, https://doi.org/10.1016/j.epidem.2023.100725

Peste des petits ruminants (PPR) is an acute infectious disease of small ruminants targeted for global eradication by 2030. The Global Strategy for Control and Eradication (GSCE) recommends mass vaccination targeting 70% coverage of small ruminant po... Read More about Modelling flock heterogeneity in the transmission of peste des petits ruminants virus and its impact on the effectiveness of vaccination for eradication.

Identifying Fibroblast Growth Factor Receptor 3 as a Mediator of Periosteal Osteochondral Differentiation through the Construction of microRNA-Based Interaction Networks (2023)
Journal Article
Wells, L. M., Roberts, H. C., Luyten, F. P., & Roberts, S. J. (2023). Identifying Fibroblast Growth Factor Receptor 3 as a Mediator of Periosteal Osteochondral Differentiation through the Construction of microRNA-Based Interaction Networks. Biology, 12(11), 1381. https://doi.org/10.3390/biology12111381

Human periosteum-derived progenitor cells (hPDCs) have the ability to differentiate towards both the chondrogenic and osteogenic lineages. This coordinated and complex osteochondrogenic differentiation process permits endochondral ossification and is... Read More about Identifying Fibroblast Growth Factor Receptor 3 as a Mediator of Periosteal Osteochondral Differentiation through the Construction of microRNA-Based Interaction Networks.

DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages (2023)
Journal Article
Subudhi, A. K., Green, J. L., Satyam, R., Salunke, R. P., Lenz, T., Shuaib, M., …Pain, A. (2023). DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages. Nature Microbiology, 8(11), 2154-2169. https://doi.org/10.1038/s41564-023-01497-6

Malaria-associated pathogenesis such as parasite invasion, egress, host cell remodelling and antigenic variation requires concerted action by many proteins, but the molecular regulation is poorly understood. Here we have characterized an essential Pl... Read More about DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages.

Can mass drug administration of moxidectin accelerate onchocerciasis elimination in Africa? (2023)
Journal Article
Kura, K., Milton, P., Hamley, J., Walker, M., Bakajika, D., Kanza, E., …Basáñez, M. (2023). Can mass drug administration of moxidectin accelerate onchocerciasis elimination in Africa?. Philosophical Transactions of the Royal Society B: Biological Sciences, 378(1887), https://doi.org/10.1098/rstb.2022.0277

Epidemiological and modelling studies suggest that elimination of Onchocerca volvulus transmission (EoT) throughout Africa may not be achievable with annual mass drug administration (MDA) of ivermectin alone, particularly in areas of high endemicity... Read More about Can mass drug administration of moxidectin accelerate onchocerciasis elimination in Africa?.

Reaching the World Health Organization elimination targets for schistosomiasis: the importance of a One Health perspective (2023)
Journal Article
Diaz, A., Walker, M., & Webster, J. (2023). Reaching the World Health Organization elimination targets for schistosomiasis: the importance of a One Health perspective. Philosophical Transactions of the Royal Society B: Biological Sciences, 378(1887), https://doi.org/10.1098/rstb.2022.0274

The past three years has seen the launch of a new World Health Organization (WHO) neglected tropical diseases (NTDs) roadmap, together with revised control and elimination guidelines. Across all, there is now a clear emphasis on the need to incorpora... Read More about Reaching the World Health Organization elimination targets for schistosomiasis: the importance of a One Health perspective.

SARS-CoV-2 evolution in the Omicron era (2023)
Journal Article
Roemer, C., Sheward, D., Hisner, R., Gueli, F., Sakaguchi, H., Frohberg, N., …Peacock, T. (2023). SARS-CoV-2 evolution in the Omicron era. Nature Microbiology, 8(11), 1952-1959. https://doi.org/10.1038/s41564-023-01504-w

Since SARS-CoV-2 BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have markedly diversified. Here we review the evolutionary trajectories and processes that underpin the emergence of these lineages, and identify the most prevalent sublinea... Read More about SARS-CoV-2 evolution in the Omicron era.

Assessing antibiotic usage data capture accuracy on dairy farms in England and Wales (2023)
Journal Article
Strang, C., Alarcon, P., Cardwell, J., & Brunton, L. (2023). Assessing antibiotic usage data capture accuracy on dairy farms in England and Wales. Veterinary Record, https://doi.org/10.1002/vetr.3505

Background: Accurate farm-level data on antibiotic usage (ABU) are needed for surveillance of antibiotic resistance. The study aim was to determine the accuracy of ABU data capture by dairy farmers in South West England and Wales. Methods: Through a... Read More about Assessing antibiotic usage data capture accuracy on dairy farms in England and Wales.

A review of human dog-bite injuries in Kitui South subcounty, Kenya (2017-2021) (2023)
Journal Article
Kungu, P., & Brodbelt, D. (2023). A review of human dog-bite injuries in Kitui South subcounty, Kenya (2017-2021). Vet Record Open, 10(2), https://doi.org/10.1002/vro2.72

IntroductionDog bites continue to be a serious public health issue due to their association with the transmission of rabies virus. In Kenya, there are no studies estimating dog-bite incidence. Annual mortalities resulting from dog-mediated rabies are... Read More about A review of human dog-bite injuries in Kitui South subcounty, Kenya (2017-2021).

Lifting laboratory rats: a survey of methods, handlers’ reasons and concerns, and rat behavioural responses (2023)
Journal Article
Burn, C., Camacho, T., & Hockenhull, J. (2023). Lifting laboratory rats: a survey of methods, handlers’ reasons and concerns, and rat behavioural responses. Applied Animal Behaviour Science, 268, Article 106077. https://doi.org/10.1016/j.applanim.2023.106077

Lifting mice by the tail is of animal welfare and scientific concern, but rat lifting methods are little researched, potentially differing from mice. Using an online questionnaire we explored different methods for lifting laboratory rats, alongside h... Read More about Lifting laboratory rats: a survey of methods, handlers’ reasons and concerns, and rat behavioural responses.

Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies (2023)
Journal Article
Barnabé, M., Elliott, J., Harris, P., & Menzies-Gow, N. (2023). Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies. Equine Veterinary Journal, https://doi.org/10.1111/evj.14012

BackgroundHypoadiponectinaemia is a risk factor for endocrinopathic laminitis, but the directionality and nature of its association with insulin dysregulation is unclear.ObjectivesTo investigate the effects of short-term induced hyperinsulinaemia and... Read More about Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies.

Prognostic factors and outcome in cats with thymic epithelial tumours: 64 cases (1999‐2021) (2023)
Journal Article
Marks, T. A., Rossanese, M., Yale, A. D., Stewart, S., Smallwood, K., Rigas, K., & Guillén, A. (in press). Prognostic factors and outcome in cats with thymic epithelial tumours: 64 cases (1999‐2021). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13675

Objectives: To describe the clinical presentation, treatment and outcomes of cats diagnosed with thymic epithelial tumours and to determine prognostic factors for survival and recurrence. Materials and Methods: Clinical records of cats diagnosed w... Read More about Prognostic factors and outcome in cats with thymic epithelial tumours: 64 cases (1999‐2021).

BEVA primary care clinical guidelines: Diagnosis and management of equine pituitary pars intermedia dysfunction (2023)
Journal Article
Menzies-Gow, N., Knowles, E., & Hart, N. (in press). BEVA primary care clinical guidelines: Diagnosis and management of equine pituitary pars intermedia dysfunction. Equine Veterinary Journal, https://doi.org/10.1111/evj.14009

Background: Pituitary pars intermedia dysfunction (PPID) is a prevalent, age-related chronic disorder in equids. Diagnosis of PPID can be challenging because of its broad spectrum of clinical presentations and disparate published diagnostic criteria,... Read More about BEVA primary care clinical guidelines: Diagnosis and management of equine pituitary pars intermedia dysfunction.

Survival to discharge and outcome of a dog following out-of-hospital cardiac arrest due to asphyxiation (2023)
Journal Article
Lang, K., Crawford, A., Hall, G., & Humm, K. (2023). Survival to discharge and outcome of a dog following out-of-hospital cardiac arrest due to asphyxiation. Vet Record Case Reports, https://doi.org/10.1002/vrc2.659

A 7-month-old dog presented with a 10-minute history of upper respiratory tract obstruction and secondary loss of consciousness in the minute before its arrival to the hospital. The dog was found to be dead on arrival. Cardiopulmonary resuscitation w... Read More about Survival to discharge and outcome of a dog following out-of-hospital cardiac arrest due to asphyxiation.