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All Outputs (242)

Determinants of Thoroughbred yearling sales price in the UK (2024)
Journal Article
Mouncey, R. R., Alarcon, P., & Verheyen, K. L. (2024). Determinants of Thoroughbred yearling sales price in the UK. Veterinary Record Open, 11(1), https://doi.org/10.1002/vro2.81

Background
Industry-level figures suggest that up to two-thirds of Thoroughbred breeding operations in the UK are unprofitable and that around half of sales transactions of Thoroughbred yearlings, commercial breeders’ predominant income source, retu... Read More about Determinants of Thoroughbred yearling sales price in the UK.

Flow sensing on dragonfly wings (2024)
Journal Article
Uhrhan, M. J., Bomphrey, R. J., & Lin, H. (2024). Flow sensing on dragonfly wings. Annals of the New York Academy of Sciences, 1536(1), 107-121. https://doi.org/10.1111/nyas.15152

One feature of animal wings is their embedded mechanosensory system that can support flight control. Insect wings are particularly interesting as they are highly deformable yet the actuation is limited to the wing base. It is established that strain... Read More about Flow sensing on dragonfly wings.

Regenerative Medicine and Biological Treatments (2024)
Book Chapter
Guest, D., Schramme, M., & Smith, R. (2024). Regenerative Medicine and Biological Treatments. In Essential Facts of Equine Physical Therapy, Rehabilitation and Sports Medicine

Many tissues undergo poor natural regeneration following injury or disease and the reparative healing process can lead to tissues that are functionally inferior and prone to re-injury. Regenerative medicine aims to induce natural tissue regeneration... Read More about Regenerative Medicine and Biological Treatments.

Variations in touch representation in the hummingbird and zebra finch forebrain (2024)
Journal Article
Gaede, A., Wu, P., & Leitch, D. (2024). Variations in touch representation in the hummingbird and zebra finch forebrain. Current Biology, 34(12), https://doi.org/10.1016/j.cub.2024.04.081

Somatosensation is essential for animals to perceive the external world through touch, allowing them to detect physical contact, temperature, pain, and body position. Studies on rodent vibrissae have highlighted the organization and processing in mam... Read More about Variations in touch representation in the hummingbird and zebra finch forebrain.

Is badger culling associated with risk compensation behaviour among cattle farmers? (2024)
Journal Article
Brunton, L., & Enticott, G. (in press). Is badger culling associated with risk compensation behaviour among cattle farmers?. Veterinary Record, https://doi.org/10.1002/vetr.4152

Background
Risk compensation theory suggests that behaviours are modified in response to interventions that remove risks by substituting them with other risky behaviours to maintain a ‘risk equilibrium’. Alternatively, risk reduction interventions m... Read More about Is badger culling associated with risk compensation behaviour among cattle farmers?.

Large-scale statistical analysis of Mycobacterium tuberculosis genome sequences identifies compensatory mutations associated with multi-drug resistance (2024)
Journal Article
Billow, N., Phelan, J., Xia, D., Peng, Y., Clark, T. G., & Chang, Y.-M. (in press). Large-scale statistical analysis of Mycobacterium tuberculosis genome sequences identifies compensatory mutations associated with multi-drug resistance. Scientific Reports, https://doi.org/10.1038/s41598-024-62946-8

Tuberculosis (TB), caused by Mycobacterium tuberculosis, has a significant impact on global health worldwide. The development of multi-drug strains that are resistant to the first-line drugs isoniazid and rifampicin threatens public health security.... Read More about Large-scale statistical analysis of Mycobacterium tuberculosis genome sequences identifies compensatory mutations associated with multi-drug resistance.

Exposure to urban particulate matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response (2024)
Journal Article
Morris, R. H., Counsell, S. J., McGonnell, I. M., & Thornton, C. (in press). Exposure to urban particulate matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response. Journal of Physiology, https://doi.org/10.1113/jp285978

World Health Organisation data suggest that up to 99% of the global population are exposed to air pollutants above recommended levels. Impacts to health range from increased risk of stroke and cardiovascular disease to chronic respiratory conditions,... Read More about Exposure to urban particulate matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response.

Exposure to Urban Particulate Matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response (2024)
Journal Article
Morris, R., Counsell, S., McGonnell, I., & Thornton, C. (in press). Exposure to Urban Particulate Matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response. Journal of Physiology, https://doi.org/10.1113/JP285978

World Health Organisation data suggest that up to 99% of the global population are exposed to air pollutants above recommended levels. Impacts to health range from increased risk of stroke and cardiovascular disease to chronic respiratory conditions,... Read More about Exposure to Urban Particulate Matter (UPM) impairs mitochondrial dynamics in BV2 cells, triggering a mitochondrial biogenesis response.

Re-evaluating the placebo response in recent canine dietary epilepsy trials (2024)
Journal Article
Schmidt, T., Meyerhoff, N., Meller, S., Twele, F., Charalambous, M., Berk, B., Law, T., Packer, R., Zanghi, B., Pan, Y., Fischer, A., & Volk, H. (2024). Re-evaluating the placebo response in recent canine dietary epilepsy trials. BMC Veterinary Research, 20(1), https://doi.org/10.1186/s12917-024-04066-z

The placebo response is a common phenomenon. Limited evidence is available about its magnitude in canine epilepsy trials, even though it can significantly influence the efficacy evaluation of new treatments. It was hypothesised that the placebo respo... Read More about Re-evaluating the placebo response in recent canine dietary epilepsy trials.

Epidemiology of heat-related illness in dogs under UK emergency veterinary care in 2022 (2024)
Journal Article
Beard, S., Hall, E. J., Bradbury, J., Carter, A. J., Gilbert, S., & O'Neill, D. G. (2024). Epidemiology of heat-related illness in dogs under UK emergency veterinary care in 2022. Herpetological Conservation and Biology, https://doi.org/10.1002/vetr.4153

Background: Dogs are exposed to increasing environmental risk for developing heat-related illness (HRI), with 2022 recorded as the hottest year to date in the UK and most of Europe. Methods: This study used VetCompass data to report the incidence ris... Read More about Epidemiology of heat-related illness in dogs under UK emergency veterinary care in 2022.

Researcher, research thyself? Mapping the landscape of canine health and welfare research funding provided by UK not-for-profit organisations from 2012–2022 (2024)
Journal Article
O'Neill, D., Skipper, A. M., & Packer, R. M. . A. (2024). Researcher, research thyself? Mapping the landscape of canine health and welfare research funding provided by UK not-for-profit organisations from 2012–2022. Herpetological Conservation and Biology, 19(5), e0303498. https://doi.org/10.1371/journal.pone.0303498

Background Research into canine health and welfare is supported by Government, charitable and private UK funding organisations. However, there is no current overall visibility or coordination of these funding activities, potentially compromising opti... Read More about Researcher, research thyself? Mapping the landscape of canine health and welfare research funding provided by UK not-for-profit organisations from 2012–2022.

Diabetes drugs activate neuroprotective pathways in models of neonatal hypoxic-ischemic encephalopathy (2024)
Journal Article
Poupon-Bejuit, L., Geard, A., Millicheap, N., Rocha-Ferreira, E., Hagberg, H., Thornton, C., & Rahim, A. A. (2024). Diabetes drugs activate neuroprotective pathways in models of neonatal hypoxic-ischemic encephalopathy. EMBO Molecular Medicine, https://doi.org/10.1038/s44321-024-00079-1

Hypoxic-ischaemic encephalopathy (HIE) arises from diminished blood flow and oxygen to the neonatal brain during labor, leading to infant mortality or severe brain damage, with a global incidence of 1.5 per 1000 live births. Glucagon-like Peptide 1 R... Read More about Diabetes drugs activate neuroprotective pathways in models of neonatal hypoxic-ischemic encephalopathy.

Environmental Land Management scheme (ELMs) (2024)
Report
Myers, J., Whatford, L., Qi, A., Cooke, R., Payne-Gifford, S., Tak, M., van Winden, S., Barling, D., & Haesler, B. (2024). Environmental Land Management scheme (ELMs). not applicable

An unprecedented set of challenges now confronts livestock food systems in Britain. With household budgets being squeezed, producers, processors, retailers and wholesalers are under increasing pressure to maintain the affordability of their products... Read More about Environmental Land Management scheme (ELMs).

Animal Health and Welfare Pathway (AHWP) (2024)
Report
Payne-Gifford, S., Myers, J., Whatford, L., Tak, M., van Winden, S., Qi, A., Haesler, B., & Barling, D. (2024). Animal Health and Welfare Pathway (AHWP). RVC Research online: not applicable

An unprecedented set of challenges now confronts livestock food systems in Britain. With household budgets being squeezed, producers, processors, retailers and wholesalers are under increasing pressure to maintain the affordability of their products... Read More about Animal Health and Welfare Pathway (AHWP).

Transparency in the beef and sheep meat food systems enables agency and fairness. (2024)
Report
Whatford, L., Payne-Gifford, S., Myers, J., Tak, M., van Winden, S., Qi, A., Barling, D., & Haesler, B. (2024). Transparency in the beef and sheep meat food systems enables agency and fairness. RVC Research online: not applicable

An unprecedented set of challenges now confronts livestock food systems in Britain. With household budgets being squeezed, producers, processors, retailers and wholesalers are under increasing pressure to maintain the affordability of their products... Read More about Transparency in the beef and sheep meat food systems enables agency and fairness..

A prospective cohort study of factors associated with the digital cushion thickness in dairy cattle (2024)
Journal Article
Griffiths, B., Barden, M., Anagnostopoulos, A., Wilson, J., Lamprou, E., Tulley, W., Bedford, C., Psifidi, A., Banos, G., & Oikonomou, G. (2024). A prospective cohort study of factors associated with the digital cushion thickness in dairy cattle. Journal of Dairy Science, 107(9), 7230-7244. https://doi.org/10.3168/jds.2023-24563

Key factors such as stage of lactation, parity, and body fat reserves have been associated with the digital cushion thickness (DCT), however, there are discrepancies between the results of previously published studies. The objective of this study was... Read More about A prospective cohort study of factors associated with the digital cushion thickness in dairy cattle.

Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion. (2024)
Journal Article
Beeston, D., Szladovits, B., & Cortellini, S. (in press). Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion. Journal of the American Veterinary Medical Association, https://doi.org/10.2460/javma.24.03.0148

Abstract
Objective
To describe the presentation, diagnosis and treatment of four cases of splenic torsion with associated spherocytosis.

Animals
Four client-owned dogs with spherocytosis and splenic torsion.

Case Presentation
Each dog prese... Read More about Spherocytosis as an indicator of fragmentation injury in dogs with splenic torsion..

Autologous bone marrow derived mesenchymal stem cells are safe for the treatment of Achilles tendinopathy (2024)
Journal Article
Goldberg, A., Masci, L., O'Donnell, P., Green, R., Brooking, D., Bassett, P., Lowdell, M., & Smith, R. (2024). Autologous bone marrow derived mesenchymal stem cells are safe for the treatment of Achilles tendinopathy. Scientific Reports, 14(1), https://doi.org/10.1038/s41598-024-61399-3

Achilles tendinopathy is a disabling condition that affects more than 50% of runners. Pre-clinical studies in a large animal model of naturally-occurring tendinopathy similar to human Achilles tendinopathy has shown benefits of autologous bone marrow... Read More about Autologous bone marrow derived mesenchymal stem cells are safe for the treatment of Achilles tendinopathy.

A screen for <i>Plasmodium falciparum</i> sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions (2024)
Journal Article
Segireddy, R., Belda, H., Yang, A., Dundas, K., Knoeckel, J., Galaway, F., Wood, L., Quinkert, D., Knuepfer, E., Treeck, M., Wright, G., & Douglas, A. (2024). A screen for Plasmodium falciparum sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions. Malaria Journal, 23(1), https://doi.org/10.1186/s12936-024-04913-2

Background Sporozoite invasion of hepatocytes is an essential step in the Plasmodium life-cycle and has similarities, at the cellular level, to merozoite invasion of erythrocytes. In the case of the Plasmodium blood-stage, efforts to identify host-pa... Read More about A screen for <i>Plasmodium falciparum</i> sporozoite surface protein binding to human hepatocyte surface receptors identifies novel host-pathogen interactions.