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Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J., Amaral, A., …Pomba, C. (2023). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Extended-spectrum beta-lactamase (ESBL)- and plasmid-mediated cephalosporinase (AmpC)-producing Enterobacterales (ESBL/AmpC-E) are an increasing healthcare problem in both human and veterinary medicine. The aim of this study was to investigate the po... Read More about Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom.

Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom (2023)
Journal Article
Menezes, J., Frosini, S., Belas, A., Marques, C., da Silva, J. M., Amaral, A. J., …Pomba, C. (in press). Longitudinal study of ESBL/AmpC-producing Enterobacterales strains sharing between cohabiting healthy companion animals and humans in Portugal and in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, https://doi.org/10.1007/s10096-023-04629-2

Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’? (2023)
Journal Article
Frosini, S., Gallow, G., Gibson, A., Menezes, J., Pomba, C., & Loeffler, A. (in press). Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’?. Microbiology Research, https://doi.org/10.3390/microbiolres14010005

Sampling animals for carriage of meticillin-resistant coagulase-positive staphylococci (MRCoPS), considered zoonotic pathogens, can be challenging and time-consuming. Developing methods to identify mecA from non-invasive samples, e.g. faeces, would b... Read More about Detecting mecA in faecal samples: a tool for assessing carriage of meticillin resistant staphylococci in pets and owners in the microbiological ‘fast age’?.

Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma (2022)
Journal Article
Azzariti, S., Bond, R., Loeffler, A., Zendri, F., Timofte, D., Chang, Y., & Pelligand, L. (2022). Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma. Antibiotics, https://doi.org/10.3390/antibiotics11091204

Fluoroquinolones (FQ) are commonly used in dogs with bacterial skin infections. Their use as first choice, along with the increased incidence of FQ-resistance, represents a risk to animal and public health. Our study determined minimum inhibitory (M... Read More about Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma.

The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households (2022)
Journal Article
Frosini, S., Bond, R., King, R. H., & Loeffler, A. (2022). The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households. Veterinary Dermatology, https://doi.org/10.1111/vde.13118

Background: Following recovery from meticillin-resistant Staphylococcus pseudintermedius (MRSP) infection of any type, dogs may continue to carry MRSP asymptomatically on skin and mucosae, contributing to the spread of this multidrug-resistant, veter... Read More about The nose is not enough: Multi-site sampling is best for MRSP detection in dogs and households.

Staphylococcus aureus lineages associated with a free-ranging population of the fruit bat Pteropus livingstonii retained over 25 years in captivity (2022)
Journal Article
Fountain, K., Barbon, A., Gibbon, M., Lloyd, D., Loeffler, A., & Feil, E. (2022). Staphylococcus aureus lineages associated with a free-ranging population of the fruit bat Pteropus livingstonii retained over 25 years in captivity. Scientific Reports, 12(1), https://doi.org/10.1038/s41598-022-17835-3

Conservation of endangered species has become increasingly complex, and costly interventions to protect wildlife require a robust scientific evidence base. This includes consideration of the role of the microbiome in preserving animal health. Captivi... Read More about Staphylococcus aureus lineages associated with a free-ranging population of the fruit bat Pteropus livingstonii retained over 25 years in captivity.

Hostage to history - questioning the duration of systemic antimicrobial therapy for the treatment of canine superficial bacterial folliculitis (2022)
Journal Article
Sousa, C., Chatfield, J., File, T., Koch, S., Leu, D., Loeffler, A., …Weese, J. (2022). Hostage to history - questioning the duration of systemic antimicrobial therapy for the treatment of canine superficial bacterial folliculitis. Journal of the American Veterinary Medical Association, 260(10), 1153-1156. https://doi.org/10.2460/javma.22.03.0113

Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii) (2021)
Journal Article
Fountain, K., Gibbon, M., Loeffler, A., & Feil, E. (2021). Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii). International Journal of Systematic and Evolutionary Microbiology, 71(3), https://doi.org/10.1099/ijsem.0.004715

The increasing availability of whole genome sequencing of bacteria has accelerated the discovery of novel species which may not have been easy to discriminate using standard phenotypic or single gene methods. Phylogenomic analysis of genome sequences... Read More about Closed genome sequences of Staphylococcus lloydii sp. nov. and Staphylococcus durrellii sp. nov. isolated from captive fruit bats (Pteropus livingstonii).

Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA) (2021)
Journal Article
Loeffler, A., Scott, C., & Frosini, S. M. (2021). Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA). Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, 49(06), 437-440. https://doi.org/10.1055/a-1624-0951

Objective Autogenous Staphylococcus pseudintermedius bacterins can reduce prescribing of antimicrobials in the management of canine recurrent pyoderma. However, increasing prevalence of meticillin-resistant, mecA-positive S. pseudintermedius (MRSP) r... Read More about Canine pyoderma: mecA persists autogenous bacterin formulation from meticillin-resistant Staphylococcus pseudintermedius (MRSP) and S. aureus (MRSA).

Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs (2021)
Journal Article
Frosini, S. M., Bond, R., King, R., Feudi, C., Schwarz, S., & Loeffler, A. (2021). Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs. BMJ Open, https://doi.org/10.1002/vetr.937

Abstract MRSP is a multidrug-resistant, zoonotic canine pathogen. This study investigated MRSP carriage and clearance through topical antimicrobial therapy and household cleaning in dogs recovered from MRSP infection. Dogs were swabbed for MRSP c... Read More about Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs.

Vetreccr R1 Text Final AL 27May21 (2021)
Journal Article
Loeffler, A., Boone, J., Boone, J., Fountain, K., Williams, J., Lloyd, D. H., …Loeffler, A. (in press). Vetreccr R1 Text Final AL 27May21. Veterinary Record,

Pinnae are vital structures for echolocation and survival in many species of bats. Pinnal lesions have been described as common in captive bats, but information on specific diseases affecting the pinnae is scarce. A collection of histological section... Read More about Vetreccr R1 Text Final AL 27May21.

Fatal Exudative Dermatitis (FED) in Island Populations of Red Squirrels (Sciurus vulgaris): Spillover of a Virulent Staphylococcus aureus Clone (ST49) From Reservoir Hosts. (2021)
Journal Article
Fountain, K., Feil, E., Blackett, T., Butler, H., Schilling, A., Meredith, A., …Feil, E. J. (2021). Fatal Exudative Dermatitis (FED) in Island Populations of Red Squirrels (Sciurus vulgaris): Spillover of a Virulent Staphylococcus aureus Clone (ST49) From Reservoir Hosts. Microbial Genomics, https://doi.org/10.1099/mgen.0.000565

Fatal exudative dermatitis (FED) is a significant cause of death of red squirrels (Sciurus vulgaris) on the island of Jersey in the Channel Islands where it is associated with a virulent clone of Staphylococcus aureus, ST49. S. aureus ST49 has been f... Read More about Fatal Exudative Dermatitis (FED) in Island Populations of Red Squirrels (Sciurus vulgaris): Spillover of a Virulent Staphylococcus aureus Clone (ST49) From Reservoir Hosts..

Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens (2020)
Journal Article
Frosini, S., Bond, R., McCarthy, A., Feudi, C., Schwarz, S., Lindsay, J., & Loeffler, A. (2020). Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens. Microorganisms, https://doi.org/10.3390/microorganisms8122031

Transmission of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus pseudintermedius (MRSP) between people and pets, and their co-carriage, are well-described. Potential exchange of antimicrobial resistance (AM... Read More about Genes on the Move: In Vitro Transduction of Antimicrobial Resistance Genes between Human and Canine Staphylococcal Pathogens.

Reduced antimicrobial prescribing during autogenous staphylococcal bacterin therapy: a retrospective study in dogs with pyoderma (2019)
Journal Article
Wilson, A., Allers, N., Lloyd, D. H., Bond, R., & Loeffler, A. (2019). Reduced antimicrobial prescribing during autogenous staphylococcal bacterin therapy: a retrospective study in dogs with pyoderma. Veterinary Record, 184(24), https://doi.org/10.1136/vr.105223

Autogenous staphylococcal bacterins are commonly mentioned as treatment for canine recurrent pyoderma but little is known about their efficacy. This retrospective study describes use and assesses efficacy of an autogenous Staphylococcus (pseud)interm... Read More about Reduced antimicrobial prescribing during autogenous staphylococcal bacterin therapy: a retrospective study in dogs with pyoderma.