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Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5 (2018)
Journal Article
Tombacz, K., Burgess, G., Holder, A. L., Werners, A., & Werling, D. (2018). Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5. Innate Immunity, https://doi.org/10.1177/1753425918798450

Toxoplasma gondii is responsible for one of the most prevalent infections in people. T. gondii profilin (TgPr) is a protein integral to parasite movement and cellular invasion. Murine TLR has been described to bind TgPr. Furthermore, more recently, h... Read More about Toxoplasma gondii profilin does not stimulate an innate immune response through bovine or human TLR5.

Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae) (2018)
Journal Article
Catalano, S., Bâ, K., Diouf, N., Léger, E., Verocai, G., & Webster, J. P. (2018). Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae). Parasitology, 146(3), 299-304. https://doi.org/10.1017/S0031182018001427

Hydatigera (Cestoda: Taeniidae) is a recently resurrected genus including species seldom investigated in sub-Saharan Africa. We surveyed wild small mammal populations in the areas of Richard Toll and Lake Guiers, Senegal, with the objective to evalua... Read More about Rodents of Senegal and their role as intermediate hosts of Hydatigera spp. (Cestoda: Taeniidae).

Anthropogenic environmental drivers of antimicrobial resistance in wildlife (2018)
Journal Article
Swift, B. M. C., Bennett, M., Waller, K., Dodd, C., Murray, A., Gomes, R. L., Humphreys, B., Hobman, J. L., Jones, M. A., Whitlock, S. E., Mitchell, L. J., Lennon, R. J., & Arnold, K. E. (2018). Anthropogenic environmental drivers of antimicrobial resistance in wildlife. Science of the Total Environment, 649, 12-20. https://doi.org/10.1016/j.scitotenv.2018.08.180

The isolation of antimicrobial resistant bacteria (ARB) from wildlife living adjacent to humans has led to the suggestion that such antimicrobial resistance (AMR) is anthropogenically driven by exposure to antimicrobials and ARB. However, ARB have al... Read More about Anthropogenic environmental drivers of antimicrobial resistance in wildlife.

Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions (2018)
Journal Article
Hoelzer, K., Bielke, L., Blake, D. P., Cox, E., Cutting, S. M., Devriendt, B., Erlacher-Vindel, E., Goossens, E., Karaca, K., Lemiere, S., Metzner, M., Raicek, M., Collell Suriñach, M., Wong, N. M., Gay, C., & Van Immerseel, F. (2018). Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions. BMC Veterinary Research, 49(70), https://doi.org/10.1186/s13567-018-0561-7

Vaccines and other alternative products are central to the future success of animal agriculture because they can help minimize the need for antibiotics by preventing and controlling infectious diseases in animal populations. To assess scientific adva... Read More about Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions.

Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs (2018)
Journal Article
Hoelzer, K., Bielke, L., Blake, D. P., Cox, E., Cutting, S. M., Devriendt, B., Erlacher-Vindel, E., Goossens, E., Karaca, K., Lemiere, S., Metzner, M., Raicek, M., Collell Suriñach, M., Wong, N. M., Gay, C., & Van Immerseel, F. (2018). Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs. BMC Veterinary Research, 49(64), https://doi.org/10.1186/s13567-018-0560-8

Vaccines and other alternative products can help minimize the need for antibiotics by preventing and controlling infectious diseases in animal populations, and are central to the future success of animal agriculture. To assess scientific advancements... Read More about Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs.

A dynamic model of transmission and elimination of peste des petits ruminants in Ethiopia (2018)
Journal Article
Fournié, G., Waret-Szkuta, A., Camacho, A., Yigezu, L. M., Pfeiffer, D. U., & Roger, F. (2018). A dynamic model of transmission and elimination of peste des petits ruminants in Ethiopia. https://doi.org/10.1073/pnas.1711646115

Peste des petits ruminants (PPR), a devastating viral disease of sheep and goats, has been targeted by the global community for eradication within the next 15 years. Although an efficacious attenuated live vaccine is available, the lack of knowledge... Read More about A dynamic model of transmission and elimination of peste des petits ruminants in Ethiopia.

Genome-wide association studies of inflammatory bowel disease in German shepherd dogs (2018)
Journal Article
Perivan, A., Bertolini, F., Rothschild, M. F., Simpson, K. W., Jergens, A. E., Allenspach, K., & Werling, D. (2018). Genome-wide association studies of inflammatory bowel disease in German shepherd dogs. PLoS ONE, 13(7), e0200685. https://doi.org/10.1371/journal.pone.0200685

Canine Inflammatory Bowel Disease (IBD) is considered a multifactorial disease caused by complex interactions between the intestinal immune system, intestinal microbiota and environmental factors in genetically susceptible individuals. Although IBD c... Read More about Genome-wide association studies of inflammatory bowel disease in German shepherd dogs.

Characterization of a novel reassortant H5N6 highly pathogenic avian influenza virus clade 2.3.4.4 in Korea, 2017 (2018)
Journal Article
Lee, E.-K., Lee, Y.-N., Kye, S.-J., Lewis, N. S., Brown, I. H., Sagong, M., Heo, G.-B., Kang, Y.-M., Cho, H.-K., Kang, H.-M., Cheon, S.-H., Lee, M., Park, B.-K., Kim, Y.-J., & Lee, Y.-J. (2018). Characterization of a novel reassortant H5N6 highly pathogenic avian influenza virus clade 2.3.4.4 in Korea, 2017. Emerging Microbes & Infections, 7(103), https://doi.org/10.1038/s41426-018-0104-3

Quantifying direct and indirect contacts for the potential transmission of infection between species using a multilayer contact network (2018)
Journal Article
Silk, M., Drewe, J., Delahay, R. J., Weber, N., Steward, L., Wilson-Aggarwal, J., Boots, M., Hodgson, D., Croft, D. P., & McDonald, R. (2018). Quantifying direct and indirect contacts for the potential transmission of infection between species using a multilayer contact network. Behaviour, 155(7-9), https://doi.org/10.1163/1568539X-00003493

Detecting opportunities for between-species transmission of pathogens can be challenging, particularly if rare behaviours or environmental transmission are involved. We present a multilayer network framework to quantify transmission potential in mult... Read More about Quantifying direct and indirect contacts for the potential transmission of infection between species using a multilayer contact network.

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control (2018)
Journal Article
Verver, S., Walker, M., Kim, Y. E., Fobi, G., Tekle, A. H., Zouré, H. G. M., Wanji, S., Boakye, D. A., Kuesel, A. C., De Vlas, S. J., Boussinesq, M., Basáñez, M.-G., & Stolk, W. A. (2018). How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control. Clinical Infectious Diseases, 66(4), S267-S274. https://doi.org/10.1093/cid/cix1137

Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa (2018)
Journal Article
Routledge, I., Walker, M., Cheke, R. A., Bhatt, S., Nkot, P. B., Matthews, G. A., Baleguel, D., Dobson, H. M., Wiles, T. L., & Basáñez, M.-G. (2018). Modelling the impact of larviciding on the population dynamics and biting rates of Simulium damnosum (s.l.): implications for vector control as a complementary strategy for onchocerciasis elimination in Africa. https://doi.org/10.1186/s13071-018-2864-y

Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination (2018)
Journal Article
Sadigh, Y., Powers, C., Spiro, S., Pedrera, M., Broadbent, A., & Nair, V. (2018). Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination. npj Vaccines, 3, 21. https://doi.org/10.1038/s41541-018-0056-6

Live herpesvirus-vectored vaccines are widely used in veterinary medicine to protect against many infectious diseases. In poultry, three strains of herpesvirus vaccines are used against Marek’s disease (MD). However, of these, only the herpesvirus of... Read More about Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination.

Whole genome amplification and exome sequencing of archived schistosome miracidia (2018)
Journal Article
Le Clec'H, W., Chevalier, F. D., McDew-White, M., Allan, F., Webster, B. L., Gouvras, A. N., Kinunghi, S., Tchuem Tchuenté, L.-A., Garba, A., Mohammed, K. A., Ame, S. M., Webster, J. P., Rollinson, D., Emery, A. M., & Anderson, T. J. (2018). Whole genome amplification and exome sequencing of archived schistosome miracidia. Parasitology, 145, 1739-1747. https://doi.org/10.1017/S0031182018000811

Adult schistosomes live in the blood vessels and cannot easily be sampled from humans, so archived miracidia larvae hatched from eggs expelled in feces or urine are commonly used for population genetic studies. Large collections of archived miracidia... Read More about Whole genome amplification and exome sequencing of archived schistosome miracidia.

SurF: an innovative framework in biosecurity and animal health surveillance evaluation (2018)
Journal Article
Muellner, P., Watts, J., Bingham, P., Bullians, M., Gould, B., Pande, A., Riding, T., Stevens, P., Vink, D., & Staerk, K. D. C. (2018). SurF: an innovative framework in biosecurity and animal health surveillance evaluation. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.12898

Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system. Surveillance evaluation should be an integral part of the surveilla... Read More about SurF: an innovative framework in biosecurity and animal health surveillance evaluation.

Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem (2018)
Journal Article
Venkatesh, D., Poen, M. J., Bestebroer, T. M., Scheuer, R. D., Vuong, O., Chkhaidze, M., Machablishvili, A., Mamuchadze, J., Ninua, L., Fedorova, N. B., Halpin, R. A., Lin, X., Ransier, A., Stockwell, T. B., Wentworth, D. E., Kriti, D., Dutta, J., Van Bakel, H., Puranik, A., Slomka, M. J., …Lewis, N. S. (2018). Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem. Journal of Virology, 92, https://doi.org/10.1128/JVI.00433-18

Wild ducks and gulls are the major reservoirs for avian influenza A viruses (AIVs). The mechanisms that drive AIV evolution are complex at sites where various duck and gull species from multiple flyways breed, winter, or stage. The Republic of Georgi... Read More about Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem.

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus (2018)
Journal Article
Kamaruzzaman, N. F., de Fatima Pina, M., Chivu, A., & Good, L. (2018). Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus. Polymers, 10(5), 521. https://doi.org/10.3390/polym10050521

The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is lim... Read More about Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus.