The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation
Journal Article
Bate, C., & Williams, A. The cellular prion protein with a monoacylated glycosylphosphatidylinositol anchor modifies cell membranes, inhibits cell signaling and reduces prion formation. Prion, 5(2), 65-68. https://doi.org/10.4161/pri.5.2.16095
Outputs (130)
Immunogenic Eimeria tenella glycosylphosphatidylinositol-anchored surface antigens (SAGs) induce inflammatory responses in avian macrophages
Journal Article
Chow, Y. P., Wan, K. L., Blake, D. P., Tomley, F. M., & Nathan, S. Immunogenic Eimeria tenella glycosylphosphatidylinositol-anchored surface antigens (SAGs) induce inflammatory responses in avian macrophages. PLoS ONE, 6(9), e25233. https://doi.org/10.1371/journal.pone.0025233
Eimeria tenella Glycosylphosphatidylinositol-anchored Surface Antigens (SAGs) Induce Inflammatory Responses in Avian Macrophages
Journal Article
Chow, Y.-P., Wan, K.-L., Blake, D. P., Tomley, F. M., & Nathan, S. Eimeria tenella Glycosylphosphatidylinositol-anchored Surface Antigens (SAGs) Induce Inflammatory Responses in Avian Macrophages. PLoS ONE, 6(9), e25233. https://doi.org/10.1371/journal.pone.0025233
Eimeria maxima phosphatidylinositol 4-phosphate 5-kinase: locus sequencing, characterization, and cross-phylum comparison
Journal Article
Goh, M., Pan, M., Blake, D. P., Wan, K., & Song, B. Eimeria maxima phosphatidylinositol 4-phosphate 5-kinase: locus sequencing, characterization, and cross-phylum comparison. Parasitology Research, 108(3), 611-620. https://doi.org/10.1007/s00436-010-2104-7
Molecular characterisation of 'strangles' outbreaks in the UK: The use of M-protein typing of Streptococcus equi ssp. equi
Journal Article
Ivens, P. A. S., Matthews, D., Webb, K., Newton, J. R., Steward, K., Waller, A. S., Robinson, C., & Slater, J. D. Molecular characterisation of 'strangles' outbreaks in the UK: The use of M-protein typing of Streptococcus equi ssp. equi. Equine Veterinary Journal, 43(3), 359-364. https://doi.org/10.1111/j.2042-3306.2010.00177.x
The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella
Journal Article
Lai, L., Bumstead, J., Liu, Y., Garnett, J., Campanero-Rhodes, M. A., Blake, D. P., Palma, A. S., Chai, W., Ferguson, D. J. P., Simpson, P., Feizi, T., Tomley, F. M., & Matthews, S. The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella. PLoS Pathogens, 7(10), e1002296. https://doi.org/10.1371/journal.ppat.1002296
Alpha-synuclein induced synapse damage is enhanced by amyloid-beta
Journal Article
Bate, C., Gentleman, S., & Williams, A. Alpha-synuclein induced synapse damage is enhanced by amyloid-beta. Molecular Neurodegeneration, 5(55), https://doi.org/10.1186/1750-1326-5-55
Polyunsaturated Fatty Acids Protect Against Prion-Mediated Synapse Damage In Vitro
Journal Article
Bate, C., Tayebi, M., Salmona, M., Diomede, L., & Williams, A. Polyunsaturated Fatty Acids Protect Against Prion-Mediated Synapse Damage In Vitro. Neurotoxicity Research, 17(3), 203-214. https://doi.org/10.1007/s12640-009-9093-2
Glycosylphosphatidylinositol Anchor Analogues Sequester Cholesterol and Reduce Prion Formation
Journal Article
Bate, C., Tayebi, M., & Williams, A. Glycosylphosphatidylinositol Anchor Analogues Sequester Cholesterol and Reduce Prion Formation. Journal of Biological Chemistry, 285(29), 22017-22026. https://doi.org/10.1074/jbc.M110.108548
Phospholipase A(2) inhibitors protect against prion and A beta mediated synapse degeneration
Journal Article
Bate, C., Tayebi, M., & Williams, A. Phospholipase A(2) inhibitors protect against prion and A beta mediated synapse degeneration. Molecular Neurodegeneration, 5(13), https://doi.org/10.1186/1750-1326-5-13
The glycosylphosphatidylinositol anchor is a major determinant of prion binding and replication
Journal Article
Bate, C., Tayebi, M., & Williams, A. The glycosylphosphatidylinositol anchor is a major determinant of prion binding and replication. Biochemical Journal, 428, 95-101. https://doi.org/10.1042/bj20091469
The Cell envelope subtilisin-like proteinase is a virulence determinant for Streptococcus suis
Journal Article
Bonifait, L., Dominguez-Punaro, M., Vaillancourt, K., Bart, C., Slater, J. D., Frenette, M., Gottschalk, M., & Grenier, D. The Cell envelope subtilisin-like proteinase is a virulence determinant for Streptococcus suis. BMC Microbiology, 10(42), 1-8. https://doi.org/10.1186/1471-2180-10-42
A Camelid Anti-PrP Antibody Abrogates PrPSc Replication in Prion-Permissive Neuroblastoma Cell Lines
Journal Article
Jones, D. R., Taylor, W. A., Bate, C., David, M., & Tayebi, M. A Camelid Anti-PrP Antibody Abrogates PrPSc Replication in Prion-Permissive Neuroblastoma Cell Lines. PLoS ONE, 5(3), https://doi.org/10.1371/journal.pone.0009804
Assessing the effectiveness of intubation as a challenge model in contagious bovine pleuropneumonia vaccine experiments
Journal Article
Nkando, I. G., Wesonga, H. O., Kuria, J. K., & McKeever, D. J. Assessing the effectiveness of intubation as a challenge model in contagious bovine pleuropneumonia vaccine experiments. Tropical Animal Health and Production, 42(8), 1743-7. https://doi.org/10.1007/s11250-010-9630-2
MODULATION OF LYMPHOCYTE PROLIFERATION AND CYTOKINE EXPRESSION BY PLACENTAL TROPHOBLAST CELLS AIDS IN MATERNAL-FETAL TOLERANCE
Presentation / Conference Contribution
Robbin, M. G., Lawrence, R. A., Wagner, B., Antczak, D. F., & De Mestre, A. M. MODULATION OF LYMPHOCYTE PROLIFERATION AND CYTOKINE EXPRESSION BY PLACENTAL TROPHOBLAST CELLS AIDS IN MATERNAL-FETAL TOLERANCE
ALTERED IMMUNE RESPONSE IN HUMAN ENDOTHELIAL CELLS AFTER DIRECT ADHERENCE OF THE INTRAVASCULAR PARASITE BRUGIA MALAYI IN VITRO
Presentation / Conference Contribution
Schroeder, H., Lawson, C., & Lawrence, R. A. ALTERED IMMUNE RESPONSE IN HUMAN ENDOTHELIAL CELLS AFTER DIRECT ADHERENCE OF THE INTRAVASCULAR PARASITE BRUGIA MALAYI IN VITRO
Glimepiride Reduces the Expression of PrPC, Prevents PrPSc Formation and Protects against Prion Mediated Neurotoxicity
Journal Article
Bate, C., Tayebi, M., Diomede, L., Salmona, M., & Williams, A. Glimepiride Reduces the Expression of PrPC, Prevents PrPSc Formation and Protects against Prion Mediated Neurotoxicity. PLoS ONE, 4(12), e8221. https://doi.org/10.1371/journal.pone.0008221
Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide
Journal Article
Wilson, R., Bate, C., Boshuizen, R., Williams, A., & Brewer, J. Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide. BMC Neuroscience, 8,Background: Neurotoxic peptides derived from the protease-resistant core of the prion protein are used to model the pathogenesis of prion diseases. The current study characterised the ingestion, internalization and intracellular trafficking of a neur... Read More about Squalestatin alters the intracellular trafficking of a neurotoxic prion peptide.
Interferon-gamma increases neuronal death in response to amyloid-beta(1-42)
Journal Article
Bate, C., Kempster, S., Last, V., & Williams, A. Interferon-gamma increases neuronal death in response to amyloid-beta(1-42). https://doi.org/10.1186/1742-2094-3-7
Mutation of the maturase lipoprotein attenuates the virulence of Streptococcus equi to a greater extent than does loss of general lipoprotein lipidation
Journal Article
Hamilton, A., Robinson, C., Sutcliffe, I. C., Slater, J. D., Maskell, D. J., Davis-Poynter, N. J., Smith, K., Waller, A., & Harrington, D. J. Mutation of the maturase lipoprotein attenuates the virulence of Streptococcus equi to a greater extent than does loss of general lipoprotein lipidation. Infection and Immunity, 74(12), 6907-6919. https://doi.org/10.1128/IAI.01116-06