Skip to main content

Research Repository

Advanced Search

Investigating the pathology of Emery-Dreifuss muscular dystrophy
Journal Article
Brown, S. C., Piercy, R. J., Muntoni, F., & Sewry, C. A. Investigating the pathology of Emery-Dreifuss muscular dystrophy. Biochemical Society Transactions, 36(Pt 6), 1335-1338. https://doi.org/10.1042/bst0361335

EDMD (Emery-Dreifuss muscular dystrophy) is caused by mutations in either the gene encoding for lamin A/C (LMNA) located at 1q21.2-q21.3 of emerin (EMD) located at Xq28. Autosomal dominant EDMD caused by LMNA mutations is more common than the X-linke... Read More about Investigating the pathology of Emery-Dreifuss muscular dystrophy.

Cornification defect in the Golden retriever: clinical, histopathological, ultrastructural and genetic characterisation
Journal Article
Cadiergues, M. C., Patel, A., Shearer, D. H., Fermor, R., Miah, S., & Hendricks, A. Cornification defect in the Golden retriever: clinical, histopathological, ultrastructural and genetic characterisation. Veterinary Dermatology, 19(3), 120-129. https://doi.org/10.1111/j.1365-3164.2008.00667.x

Veterinarians have recognised a nonpruritic skin disease in the Golden retriever breed characterised by excessive scaling of large, variably pigmented flakes of skin in otherwise healthy dogs. This prospective case series describes clinical, histopat... Read More about Cornification defect in the Golden retriever: clinical, histopathological, ultrastructural and genetic characterisation.

The role of nutrients in modulating disease
Journal Article
Chan, D. L. The role of nutrients in modulating disease. Journal of Small Animal Practice, 49(6), 266-271. https://doi.org/10.1111/j.1748-5827.2008.00589.x

The role of nutrition in the management of diseases has often centred on correcting apparent nutrient deficiencies or meeting estimated nutritional requirements of patients. Nutrition has traditionally been considered a supportive measure akin to flu... Read More about The role of nutrients in modulating disease.

Circulating natriuretic peptides in cats with heart disease
Journal Article
Connolly, D. J., Magalhaes, R. J. S., Syme, H. M., Boswood, A., Fuentes, V. L., Chu, L., & Metcalf, M. Circulating natriuretic peptides in cats with heart disease. Journal of Veterinary Internal Medicine, 22(1), 96-105. https://doi.org/10.1111/j.1939-1676.2007.0024.x

Background: Circulating natriuretic peptide concentrations are increased in cats with myocardial dysfunction. Hypothesis: Serum N-terminal fragment of proatrial natriuretic peptide (NT-proANP) and NT-probrain natriuretic peptide (proBNP) concentratio... Read More about Circulating natriuretic peptides in cats with heart disease.

Equine recurrent airway obstruction and insect bite hypersensitivity: Understanding the diseases and uncovering possible new therapeutic approaches
Journal Article
Cunningham, F. M., & Dunkel, B. Equine recurrent airway obstruction and insect bite hypersensitivity: Understanding the diseases and uncovering possible new therapeutic approaches. https://doi.org/10.1016/j.tvjl.2007.10.005

Recurrent airway obstruction (RAO) and insect bite hypersensitivity (IBH) are allergic conditions that are commonly encountered in the horse. Whilst complete allergen avoidance is an effective management strategy for both diseases, this may not be ac... Read More about Equine recurrent airway obstruction and insect bite hypersensitivity: Understanding the diseases and uncovering possible new therapeutic approaches.

Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations
Journal Article
Davison, L. J., Walding, B. R., Herrtage, M. E., & Catchpole, B. Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations. Journal of Veterinary Internal Medicine, 22(6), 1317-1325. https://doi.org/10.1111/j.1939-1676.2008.0194.x

Background: Anti-insulin antibodies (AIA) occur in diabetic dogs after insulin therapy, although their clinical significance is unclear. Hypothesis: Treatment of diabetic dogs with heterologous insulin is more likely to stimulate production of AIA th... Read More about Anti-Insulin Antibodies in Diabetic Dogs Before and After Treatment with Different Insulin Preparations.

Uterine horn torsion in a non-gravid cat
Journal Article
De La Puerta, B., McMahon, L. A., & Moores, A. Uterine horn torsion in a non-gravid cat. Journal of Feline Medicine and Surgery, 10(4), 395-397. https://doi.org/10.1616/j.jfms.2008.01.004

An 11-year-old female domestic shorthair cat with a previous history of having been spayed, presented with signs of abdominal distension, lethargy and anorexia of I week's duration. On the basis of radiological and ultrasonographic findings a tentati... Read More about Uterine horn torsion in a non-gravid cat.

Peripheral washout phenomenon in an animal tumour model: comparison of dynamic magnetic resonance imaging using a small molecular contrast medium with histology
Journal Article
Drees, R., Huenigen, H., Wagner, S., Schnorr, J., Plendl, J., & Taupitz, M. Peripheral washout phenomenon in an animal tumour model: comparison of dynamic magnetic resonance imaging using a small molecular contrast medium with histology. Veterinary and Comparative Oncology, 6(3), 151-161. https://doi.org/10.1111/j.1476-5829.2007.00156.x

Diagnosis and treatment of non-infectious and infectious foal diarrhoea
Journal Article
Dunkel, B. Diagnosis and treatment of non-infectious and infectious foal diarrhoea

Diarrhoea is a common problem affecting fools of all ages. Common non-infectious causes of mild to moderate diarrhoea include foal heat diarrhoea and nutritionally induced diarrhoea. Clinical signs often resolve spontaneously without or with only min... Read More about Diagnosis and treatment of non-infectious and infectious foal diarrhoea.

Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1
Journal Article
Fernandez-Fuente, M., Ames, E. G., Wagner, M. L., Zhou, H., Strom, M., Zammit, P. S., Mickelson, J. R., Muntoni, F., Brown, S. C., & Piercy, R. J. Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1. American Journal of Veterinary Research, 69(12), 1637-1645. https://doi.org/10.2460/ajvr.69.12.1637

Objective - To develop a reliable method for converting cultured equine skin-derived fibroblasts into muscle cells. Sample Population - Equine skin-derived fibroblasts. Procedures - The equine myogenic differentiation 1 (eqMyoD) genomic sequence was... Read More about Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1.