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Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin
Journal Article
Menzies-Gow, N. J., Bailey, S. R., Berhane, Y., Brooks, A. C., & Elliott, J. Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin. American Journal of Veterinary Research, 69(3), 349-355

Objective - To determine the effect of endotoxin (lipopolysaccharide [LPS]) on vasoactive mediator production by cultured equine digital vein endothelial cells (EDVECs). Sample Population - EDVECs obtained from forelimb digital veins of 7 healthy adu... Read More about Evaluation of the induction of vasoactive mediators from equine digital vein endothelial cells by endotoxin.

Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses
Journal Article
Menzies-Gow, N. J., Sepulveda, M. F., Bailey, S. R., Cunningham, F. M., & Elliott, J. Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses. American Journal of Veterinary Research, 69(2), 199-207. https://doi.org/10.2460/ajvr.69.2.199

Objective-To evaluate the roles of 5-hydroxytryptamine (5-HT), thromboxane A(2) (TxA(2) and platelet-activating factor (PAF) in endotoxin-induced digital hypoperfusion in horses. Animals-6 healthy adult Thoroughbreds. Procedures-Horses were treated w... Read More about Roles of thromboxane A2 and 5-hydroxytryptamine in endotoxin-induced digital vasoconstriction in horses.

The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses
Journal Article
Moffat, P. A., Firth, E. C., Rogers, C. W., Smith, R. K. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Mcilwraith, C. W., & Van Weeren, P. R. The influence of exercise during growth on ultrasonographic parameters of the superficial digital flexor tendon of young Thoroughbred horses. Equine Veterinary Journal, 40(2), 136-140. https://doi.org/10.2746/042516408x253109

Reasons for performing study: Conditioning by early training may influence the composition of certain musculoskeletal tissues, but very few data exist on its effect during growth on tendon structure and function.

Computed tomography versus arthroscopy for detection of canine elbow dysplasia lesions
Journal Article
Moores, A. P., Benigni, L., & Lamb, C. R. Computed tomography versus arthroscopy for detection of canine elbow dysplasia lesions. Veterinary Surgery, 37(4), 390-398. https://doi.org/10.1111/j.1532-950X.2008.00393.x

Objective-To describe associations between computed tomography (CT) and arthroscopy in dogs with elbow dysplasia lesions. Study Design-Retrospective clinical study. Sample Population-Canine elbows (n = 101) investigated by CT and arthroscopy. Methods... Read More about Computed tomography versus arthroscopy for detection of canine elbow dysplasia lesions.

Computed tomography as an aid to management of chronic oropharyngeal stick injury in the dog
Journal Article
Nicholson, I., Halfacree, Z. J., Whatmough, C., Mantis, P., & Baines, S. J. Computed tomography as an aid to management of chronic oropharyngeal stick injury in the dog. Journal of Small Animal Practice, 49(9), 451-457. https://doi.org/10.1111/j.1748-5827.2008.00591.x

OBJECTIVE: To describe the use of computed tomography scanning in the management of dogs with chronic signs after oropharyngeal stick injury. METHODS: Dogs with a final diagnosis of chronic oropharyngeal stick injury that underwent a computed tomogra... Read More about Computed tomography as an aid to management of chronic oropharyngeal stick injury in the dog.

Reply to giannoulopoulos
Journal Article
Niessen, S. J. M., Voyce, M., Hargreaves, J., & Syme, H. M. Reply to giannoulopoulos. Journal of Small Animal Practice, 49(6), 319-319

High-speed gallop locomotion in the Thoroughbred racehorse. II. The effect of incline on centre of mass movement and mechanical energy fluctuation
Journal Article
Parsons, K. J., Pfau, T., Ferrari, M., & Wilson, A. M. High-speed gallop locomotion in the Thoroughbred racehorse. II. The effect of incline on centre of mass movement and mechanical energy fluctuation. Journal of Experimental Biology, 211(6), 945-956. https://doi.org/10.1242/jeb.006692

During locomotion on an incline, mechanical work is performed to move an animal up the slope and increase the potential energy ( PE) of the trunk and hence the centre of mass ( CoM). Thus, at a given speed the total net mechanical work increases with... Read More about High-speed gallop locomotion in the Thoroughbred racehorse. II. The effect of incline on centre of mass movement and mechanical energy fluctuation.

High-speed gallop locomotion in the Thoroughbred racehorse. I. The effect of incline on stride parameters
Journal Article
Parsons, K. J., Pfau, T., & Wilson, A. M. High-speed gallop locomotion in the Thoroughbred racehorse. I. The effect of incline on stride parameters. Journal of Experimental Biology, 211(6), 935-944. https://doi.org/10.1242/Jeb.006650

During locomotion up an incline, power is required to elevate the centre of mass. This is provided when the animal's limbs are in contact with the ground. Measurements of stride timing variables from multiple limbs during high speed, over-ground loco... Read More about High-speed gallop locomotion in the Thoroughbred racehorse. I. The effect of incline on stride parameters.

Aorto-iliac thromboembolism secondary to infectious endocarditis causing paraparesis in a puppy
Journal Article
Penning, V., Benigni, L., Connolly, D. J., Chandler, K. E., Smyth, B., Rycroft, A. N., & Whatmough, C. Aorto-iliac thromboembolism secondary to infectious endocarditis causing paraparesis in a puppy. Companion Animal, 13(7), 57-62. https://doi.org/10.1111/j.2044-3862.2008.tb00317.x

A 10-week-old-female Rhodesian Ridgeback was referred for right pelvic limb lameness following a fall. A grade IV/VI left atrioventricular (AV) valve murmur and reduced femoral pulses were detected. On neurological examination the puppy was non-ambul... Read More about Aorto-iliac thromboembolism secondary to infectious endocarditis causing paraparesis in a puppy.

Regionalisation of the muscle fascicle architecture in the equine longissimus dorsi muscle
Journal Article
Ritruechai, P., Weller, R., & Wakeling, J. M. Regionalisation of the muscle fascicle architecture in the equine longissimus dorsi muscle. Equine Veterinary Journal, 40(3), 246-251. https://doi.org/10.2746/042516408x273675

Reasons for performing study: The longissimus dorsi is the largest muscle in the equine back and plays an important role in locomotor ability and performance in the horse. In vivo studies suggest that the mechanical function varies between different... Read More about Regionalisation of the muscle fascicle architecture in the equine longissimus dorsi muscle.

Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth
Journal Article
Rogers, C. W., Firth, E. C., McIlwraitht, C. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Smith, R. K. W., & Van Weeren, P. R. Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth. Equine Veterinary Journal, 40(2), 111-118. https://doi.org/10.2746/042516408x268923

Reasons for performing study: No data exist on the intensity of exercise required or on possible harmful effects of increasing exercise in foals over the natural level when free at pasture.

Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: The effects on 2-and 3-year-old racing careers
Journal Article
Rogers, C. W., Firth, E. C., Mcilwraith, C. W., Barneveld, A., Goodship, A. E., Kawcak, C. E., Smith, R. K. W., & Van Weeren, P. R. Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: The effects on 2-and 3-year-old racing careers. Equine Veterinary Journal, 40(2), 119-127. https://doi.org/10.2746/042516408x266088

Reasons for performing study: No data exist on the effects of conditioning exercise at foal age on workload and subsequent clinical injury rate during their 2- and 3-year-old racing careers.

Clinical signs, histology, and CD3-positive cells before and after treatment of dogs with chronic enteropathies
Presentation / Conference Contribution
Schreiner, N. M. S., Gaschen, F., Grone, A., Sauter, S. N., & Allenspach, K. Clinical signs, histology, and CD3-positive cells before and after treatment of dogs with chronic enteropathies

Background: Histopathology is widely used for the diagnosis of inflammatory bowel disease in dogs. Variations in lesions and unavailability of uniform grading systems limit the usefulness of histologic examination.