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Sedative effects of intramuscular alfaxalone in pet guinea pigs (Cavia porcellus) (2018)
Journal Article
D'Ovidio, D., Marino, F., Noviello, E., Lanaro, E., Monticelli, P., & Adami, C. (2018). Sedative effects of intramuscular alfaxalone in pet guinea pigs (Cavia porcellus). Veterinary Anaesthesia and Analgesia, 45(2), 183-189. https://doi.org/10.1016/j.vaa.2017.08.004

Objective: To evaluate the efficacy and side effects of alfaxalone administered intramuscularly (IM) as a sedative agent in guinea pigs undergoing survey radiographs.

Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation (2018)
Journal Article
McAulay, G., Borgeat, K. A., Sargent, J., Mõtsküla, P., Neves, J., Dukes-McEwan, J., & Fuentes, V. L. (2018). Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation. https://doi.org/10.1016/j.tvjl.2018.02.015

The aim of this study was to describe the clinical phenotype of Dogue de Bordeaux (DdB) referred for cardiac investigation, with particular reference to the prevalence of atrial fibrillation and associated features. Review of canine medical records o... Read More about Phenotypic description of cardiac findings in a population of Dogue de Bordeaux with an emphasis on atrial fibrillation.

Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs (2018)
Journal Article
Sanchez, L., Beltran, E., De Stefani, A., Guo, L. T., Shea, A., Shelton, D., De Risio, L., & Burmeister, L. M. (2018). Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs. PLoS ONE, 13(23), e0193372. https://doi.org/10.1371/journal.pone.0193372

Four full-sibling intact male Miniature Poodles were evaluated at 4–19 months of age. One was clinically normal and three were affected. All affected dogs were reluctant to exercise and had generalised muscle atrophy, a stiff gait and a markedly elev... Read More about Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs.

Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease (2018)
Journal Article
Van Den Broek, D. H. N., Geddes, R. F., Williams, T. L., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease. Journal of Veterinary Internal Medicine, 32(2), 727-735. https://doi.org/10.1111/jvim.15051

Background:
Hypercalcemia is commonly associated with chronic kidney disease (CKD) in cats.

Objectives:
To explore the calcitonin response to naturally occurring ionized hypercalcemia in cats with azotemic CKD, and to assess the relationship of... Read More about Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease.

Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats (2018)
Journal Article
Geddes, R. F., Jepson, R. E., Forcada, Y., Elliott, J., & Syme, H. M. (2018). Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats. https://doi.org/10.1016/j.tvjl.2018.02.010

Feline chronic kidney disease (CKD) is associated with high variability in severity of CKD-mineral and bone disorder (CKD-MBD). The calcium sensing receptor (CaSR) regulates circulating parathyroid hormone (PTH) and calcium concentrations. Single nuc... Read More about Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats.

Caudal articular process dysplasia of thoracic vertebrae in neurologically normal French bulldogs, English bulldogs, and Pugs: Prevalence and characteristics (2018)
Journal Article
Bertram, S., Ter Haar, G., & De Decker, S. (2018). Caudal articular process dysplasia of thoracic vertebrae in neurologically normal French bulldogs, English bulldogs, and Pugs: Prevalence and characteristics. https://doi.org/10.1111/vru.12609

The aims of this study were to evaluate the prevalence and anatomical characteristics of thoracic caudal articular process dysplasia in French bulldogs, English bulldogs and Pugs presenting for problems unrelated to spinal disease. In this retrospect... Read More about Caudal articular process dysplasia of thoracic vertebrae in neurologically normal French bulldogs, English bulldogs, and Pugs: Prevalence and characteristics.

Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry (2018)
Journal Article
Pittaway, R., Wu, Y., Suárez-Bonnet, A., Szladovits, B., Scurrell, E. J., Garden, O. A., Polton, G., & Priestnall, S. L. (2018). Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718760965

Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large pleomorphic cells that express CD30. Null-cell lymphoma has also been described in dogs when neither... Read More about Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry.

Cognitive dysfunction in naturally occurring canine idiopathic epilepsy (2018)
Journal Article
Packer, R. M. A., McGreevy, P. D., Salvin, H. E., Valenzuela, M. J., Chaplin, C. M., & Volk, H. A. (2018). Cognitive dysfunction in naturally occurring canine idiopathic epilepsy. PLoS ONE, 13(2), e0192182. https://doi.org/10.1371/journal.pone.0192182

Globally, epilepsy is a common serious brain disorder. In addition to seizure activity, epilepsy is associated with cognitive impairments including static cognitive impairments present at onset, progressive seizure-induced impairments and co-morbid d... Read More about Cognitive dysfunction in naturally occurring canine idiopathic epilepsy.

Longitudinal changes in telomere length and associated genetic parameters in dairy cattle analysed using random regression models (2018)
Journal Article
Seeker, L. A., Ilska, J. J., Psifidi, A., Wilbourn, R. V., Underwood, S. L., Fairlie, J., Holland, R., Froy, H., Bagnall, A., Whitelaw, B., Coffey, M., Nussey, D. H., & Banos, G. (2018). Longitudinal changes in telomere length and associated genetic parameters in dairy cattle analysed using random regression models. PLoS ONE, 13(2), https://doi.org/10.1371/journal.pone.0192864

Telomeres cap the ends of linear chromosomes and shorten with age in many organisms. In humans short telomeres have been linked to morbidity and mortality. With the accumulation of longitudinal datasets the focus shifts from investigating telomere le... Read More about Longitudinal changes in telomere length and associated genetic parameters in dairy cattle analysed using random regression models.

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS) (2018)
Journal Article
Kondori, N. R., Paul, P., Robbins, J. P., Liu, K., Hildyard, J. C. W., Wells, D. J., & De Belleroche, J. S. (2018). Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS). Frontiers in Molecular Biosciences, 5(8), https://doi.org/10.3389/fmolb.2018.00008

Highly pathogenic avian influenza (HPAI) H5N1 virus has been circulating in Vietnam since 2003, while outbreaks of HPAI H5N6 virus are more recent, having only been reported since 2014. Although the spatial distribution of H5N1 outbreaks and risk fac... Read More about Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS).

Isolation and identification of Acinetobacter spp. from healthy canine skin (2018)
Journal Article
Mitchell, K. E., Turton, J. F., & Lloyd, D. H. (2018). Isolation and identification of Acinetobacter spp. from healthy canine skin. Veterinary Dermatology, 29(3), 240+. https://doi.org/10.1111/vde.12528

Acinetobacter species can exhibit widespread resistance to antimicrobial agents. They are already recognized as important nosocomial pathogens of humans, but are becoming increasingly recognized in opportunistic infections of animals. This study aime... Read More about Isolation and identification of Acinetobacter spp. from healthy canine skin.

Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury (2018)
Journal Article
Hu, H. Z., Granger, N., Pai, S. B., Bellamkonda, R. V., & Jeffery, N. D. (2018). Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury. Brain, 141, 1017-1027. https://doi.org/10.1093/brain/awy007

Many hundreds of thousands of people around the world are living with the long-term consequences of spinal cord injury and they need effective new therapies. Laboratory research in experimental animals has identified a large number of potentially tra... Read More about Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury.

Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin (2018)
Journal Article
Gostelow, R., Hazuchova, K., Scudder, C., Forcada, Y., Church, D. B., & Niessen, S. J. M. (2018). Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin. Journal of Feline Medicine and Surgery, 20(2), 114-121. https://doi.org/10.1177/1098612X17697482

Objectives The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR).

Methods Recently diagnosed (

Abdominal trauma in dogs 2. management (2018)
Journal Article
Cortellini, S., & Humm, K. R. (2018). Abdominal trauma in dogs 2. management. In Practice, 40, 2-10. https://doi.org/10.1136/inp.k51

Trauma represents a big challenge for emergency doctors both in human and veterinary medicine. There have been great advancements in trauma medicine in people and these often provide an inspiration for veterinary surgeons. However, the vast differenc... Read More about Abdominal trauma in dogs 2. management.