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X Chromosome Evolution in Cetartiodactyla (2017)
Journal Article
Proskuryakova, A. A., Kulemzina, A. I., Perelman, P. L., Makunin, I. A., Larkin, D. M., Farré, M., Kukekova, V. A., Lynn Johnson, J., Lemskaya, A. N., Beklemisheva, R. V., Roelke-Parker, E. M., Bellizzi, J., Ryder, A. O., O’Brien, J. S., & Graphodatsky, S. A. (2017). X Chromosome Evolution in Cetartiodactyla. Genes, 8(9), 216. https://doi.org/10.3390/genes8090216

The phenomenon of a remarkable conservation of the X chromosome in eutherian mammals has been first described by Susumu Ohno in 1964. A notable exception is the cetartiodactyl X chromosome, which varies widely in morphology and G-banding pattern betw... Read More about X Chromosome Evolution in Cetartiodactyla.

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing (2017)
Journal Article
Godinho, M. S., Thorpe, C. T., Greenwald, S. E., & Screen, H. R. (2017). Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing. https://doi.org/10.1038/s41598-017-09995-4

Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sli... Read More about Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing.

Where food safety meets nutrition outcomes in livestock and fish value chains: a conceptual approach (2017)
Journal Article
Haesler, B., Dominguez-Salas, P., Fornace, K. M., Garza, M., Grace, D., & Rushton, J. (2017). Where food safety meets nutrition outcomes in livestock and fish value chains: a conceptual approach. Food Security, 9(5), 1001-1007. https://doi.org/10.1007/s12571-017-0710-2

There is increasing interest in the links between food safety and nutrition. Animal-source foods contribute to fulfilling important micronutrient requirements by supplying vitamin B12, high quality protein, iron, zinc, vitamin A of high bioavailabili... Read More about Where food safety meets nutrition outcomes in livestock and fish value chains: a conceptual approach.

The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks (2017)
Journal Article
Carron, M., Alarcon, P., Karani, M., Muinde, P., Akoko, J., Onono, J., Fèvre, E. M., Haesler, B., & Rushton, J. (2017). The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks. Preventive Veterinary Medicine, 147, 90-99. https://doi.org/10.1016/j.prevetmed.2017.08.013

Livestock food systems play key subsistence and income generation roles in low to middle income countries and are important networks for zoonotic disease transmission. The aim of this study was to use a value chain framework to characterize the broil... Read More about The broiler meat system in Nairobi, Kenya: using a value chain framework to understand animal and product flows, governance and sanitary risks.

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., Chang, Y. M., Priestnall, S. L., Stanzani, G., Davies, N., Mookerjee, R., Jalan, R., & Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers (2017)
Journal Article
Nolan, W., McHale-Owen, H., & Bate, C. (2017). Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers. Biochemical Journal, 474(17), 3045-3058. https://doi.org/10.1042/BCJ20170239

The production of amyloid-β (Aβ) is a key factor driving pathogenesis in Alzheimer's disease (AD). Increasing concentrations of soluble Aβ oligomers within the brain lead to synapse degeneration and the progressive dementia characteristic of AD. Sinc... Read More about Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers.

Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis (2017)
Journal Article
Crawford, A. H., Stoll, A. L., Sanchez-Masian, D., Shea, A., Michaels, J., Fraser, A. R., & Beltran, E. (2017). Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis. Journal of Veterinary Internal Medicine, 31(5), 1477-1486. https://doi.org/10.1111/jvim.14791

Background: Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Informat... Read More about Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis.

Comparison of veterinary drugs and veterinary homeopathy: part 2 (2017)
Journal Article
Lees, P., Chambers, D., Pelligand, L., Toutain, P. L., Whiting, M., & Whitehead, M. L. (2017). Comparison of veterinary drugs and veterinary homeopathy: part 2. Veterinary Record, 181, 198-207. https://doi.org/10.1136/vr.104279

Part 2 of this narrative review outlines the theoretical and practical bases for assessing the efficacy and effectiveness of conventional medicines and homeopathic products. Known and postulated mechanisms of action are critically reviewed. The evide... Read More about Comparison of veterinary drugs and veterinary homeopathy: part 2.

Dynamic Lumbosacral Magnetic Resonance Imaging in a Dog with Tethered Cord Syndrome with a Tight Filum Terminale (2017)
Journal Article
De Decker, S., Watts, V., & Neilson, D. M. (2017). Dynamic Lumbosacral Magnetic Resonance Imaging in a Dog with Tethered Cord Syndrome with a Tight Filum Terminale. Frontiers in Veterinary Science, 4(134), https://doi.org/10.3389/fvets.2017.00134

A 1-year and 11-month- old English Cocker Spaniel was evaluated for clinical signs of progressive right pelvic limb lameness and urinary incontinence. Neurological examination was suggestive of a lesion localized to the L4–S3 spinal cord segments. No... Read More about Dynamic Lumbosacral Magnetic Resonance Imaging in a Dog with Tethered Cord Syndrome with a Tight Filum Terminale.

Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study (2017)
Journal Article
Kenward, H., Elliott, J., Lee, T., & Pelligand, L. (2017). Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study. BMC Veterinary Research, 13(1), 244. https://doi.org/10.1186/s12917-017-1156-7

Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure ch... Read More about Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study.

The genomic architecture of mastitis resistance in dairy sheep (2017)
Journal Article
Banos, G., Bramis, G., Bush, S. J., Clark, E. L., McCulloch, M. E. B., Smith, J., Schulze, G., Arsenos, G., Hume, D. A., & Psifidi, A. (2017). The genomic architecture of mastitis resistance in dairy sheep. BMC Genomics, 18, 624. https://doi.org/10.1186/s12864-017-3982-1

Mastitis is the most prevalent disease in dairy sheep with major economic, hygienic and welfare implications. The disease persists in all dairy sheep production systems despite the implementation of improved management practises. Selective breeding f... Read More about The genomic architecture of mastitis resistance in dairy sheep.

A quantitative evaluation of physical and digital approaches to centre of mass estimation (2017)
Journal Article
Macaulay, S., Hutchinson, J. R., & Bates, K. T. (2017). A quantitative evaluation of physical and digital approaches to centre of mass estimation. Journal of Anatomy, 231(5), 758-775. https://doi.org/10.1111/joa.12667

Centre of mass is a fundamental anatomical and biomechanical parameter. Knowledge of centre of mass is essential to inform studies investigating locomotion and other behaviours, through its implications for segment movements, and on whole body factor... Read More about A quantitative evaluation of physical and digital approaches to centre of mass estimation.

Veterinary student competence in equine lameness recognition and assessment: a mixed methods study (2017)
Journal Article
Starke, S. D., & May, S. A. (2017). Veterinary student competence in equine lameness recognition and assessment: a mixed methods study. Veterinary Record, 181(168), https://doi.org/10.1136/vr.104245

The development of perceptual skills is an important aspect of veterinary education. The authors investigated veterinary student competency in lameness evaluation at two stages, before (third year) and during (fourth/fifth year) clinical rotations. S... Read More about Veterinary student competence in equine lameness recognition and assessment: a mixed methods study.

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments) (2017)
Journal Article
Percie Du Sert, N., Alfieri, A., Allan, S. M., Carswell, H. V. O., Deuchar, G. A., Farr, T. D., Flecknell, P. A., Gallagher, L., Gibson, C. L., Haley, M. J., Macleod, M. R., McColl, B. W., McCabe, C., Morancho, A., Moon, L. D. F., O’Neill, M. J., Pérez De Puig, I., Planas, A., Ragan, C. I., Rosell, A., …Macrae, I. M. (2017). The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments). https://doi.org/10.1177/0271678X17709185

Comparison of veterinary drugs and veterinary homeopathy: part 1 (2017)
Journal Article
Lees, P., Chambers, D., Pelligand, L., Toutain, P. L., Whiting, M., & Whitehead, M. L. (2017). Comparison of veterinary drugs and veterinary homeopathy: part 1. Veterinary Record, 181(7), 170-176. https://doi.org/10.1136/vr.104278

For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of v... Read More about Comparison of veterinary drugs and veterinary homeopathy: part 1.

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis (2017)
Journal Article
Kamaruzzaman, N. F., Chong, S. Q. Y., Edmondson-Brown, K. M., Ntow-Boahene, W., Bardiau, M., & Good, L. (2017). Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis. Frontiers in Microbiology, 11(8), 1518. https://doi.org/10.3389/fmicb.2017.01518

Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into u... Read More about Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis.