C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints? (2018)
Journal Article
Brocal, J., De Decker, S., José-López, R., Manzanilla, E. G., Penderis, J., Stalin, C., Bertram, S., Schoenebeck, J. J., Rusbridge, C., Fitzpatrick, N., & Gutierrez-Quintana, R. (2018). C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?. Journal of Anatomy, https://doi.org/10.1111/joa.12822

The number of cervical vertebrae in mammals is almost constant at seven, regardless of their neck length, implying that there is selection against variation in this number. Homebox (Hox) genes are involved in this evolutionary mammalian conservation,... Read More about C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?.

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus (2018)
Journal Article
Kamaruzzaman, N. F., de Fatima Pina, M., Chivu, A., & Good, L. (2018). Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus. Polymers, 10(5), 521. https://doi.org/10.3390/polym10050521

The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is lim... Read More about Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus.

Does ‘hacking’ surface type affect equine forelimb foot placement, movement symmetry or hoof impact deceleration during ridden walk and trot exercise (2018)
Journal Article
Barstow, A., Bailey, J., Campbell, J., Harris, C., Weller, R., & Pfau, T. (2018). Does ‘hacking’ surface type affect equine forelimb foot placement, movement symmetry or hoof impact deceleration during ridden walk and trot exercise. Equine Veterinary Journal, https://doi.org/10.1111/evj.12952

Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy (2018)
Journal Article
Spalla, I., Payne, J. R., Borgeat, K. A., Fuentes, V. L., & Connolly, D. J. (2018). Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy. Journal of Veterinary Cardiology, 20(3), 154-164. https://doi.org/10.1016/j.jvc.2018.04.005

Hypertrophic cardiomyopathy (HCM) has a variable prognosis; left atrial size, presence of clinical signs and left ventricular systolic function have been shown to predict outcomes. Mitral annular plane systolic excursion (MAPSE) and tricuspid annular... Read More about Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy.

Use of ultrasonography to confirm epidural catheter position in a cat (2018)
Journal Article
Machin, H., Merlin, T., & Viscasillas, J. (2018). Use of ultrasonography to confirm epidural catheter position in a cat. Veterinary Anaesthesia and Analgesia, https://doi.org/10.1016/j.vaa.2018.03.012

Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures (2018)
Journal Article
Osagie-Clouard, L., Kaufmann, J., Blunn, G., Coathup, M., Pendegrass, C., Meeson, R. L., Briggs, T., & Moazen, M. (2018). Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures. Journal of Orthopaedic Research, https://doi.org/10.1002/jor.24034

The use of external fixators allows for the direct investigation of newly formed interfragmentary bone, and the radiographic evaluation of the fracture. We validated the results of a finite element model with the in vitro stiffness' of two widely use... Read More about Biomechanics of Two External Fixator Devices Used in Rat Femoral Fractures.

Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013 (2018)
Journal Article
O'Neill, D. G., Baral, L., Church, D. B., Brodbelt, D. C., & Packer, R. M. A. (2018). Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013. Canine Genetics and Epidemiology, 5(3), https://doi.org/10.1186/s40575-018-0057-9

Approach to canine paroxysmal dyskinesias (2018)
Journal Article
Posporis, C., Wyatt, S., & Wessmann, A. (2018). Approach to canine paroxysmal dyskinesias. Companion Animal, 23(5), https://doi.org/10.12968/coan.2018.23.5.276

The term ‘paroxysmal dyskinesia’ (PD) describes a manifestation of involuntary movement or muscle tone,
which by definition is episodic in nature and self-limiting. The PDs remain poorly understood and frequently
under-recognised conditions in vete... Read More about Approach to canine paroxysmal dyskinesias.

First anatomical network analysis of fore- and hindlimb musculoskeletal modularity in bonobos, common chimpanzees, and humans (2018)
Journal Article
Diogo, R., Molnar, J. L., Rolian, C., & Esteve-Altava, B. (2018). First anatomical network analysis of fore- and hindlimb musculoskeletal modularity in bonobos, common chimpanzees, and humans. https://doi.org/10.1038/s41598-018-25262-6

Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the... Read More about First anatomical network analysis of fore- and hindlimb musculoskeletal modularity in bonobos, common chimpanzees, and humans.

Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A (2018)
Journal Article
De Ridder, D., Marino, S., Bishop, R. T., Renema, N., Chenu, C., Heymann, D., & Idris, A. I. (2018). Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A. https://doi.org/10.1038/s41598-018-25290-2

Semaphorin 3A (Sema3A), a secreted member of the Semaphorin family, increases osteoblast differentiation, stimulates bone formation and enhances fracture healing. Here, we report a previously unknown role of Sema3A in the regulation of ectopic bone f... Read More about Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A.

Postoperative survival and early complications after intracranial surgery in dogs (2018)
Journal Article
Forward, A. K., Volk, H. A., & De Decker, S. (2018). Postoperative survival and early complications after intracranial surgery in dogs. Vector-Borne and Zoonotic Diseases, 47(4), 549-554. https://doi.org/10.1111/vsu.12785

Objective
To describe survival and early postoperative outcome after intracranial surgery in dogs.

Study design
Retrospective case series.

Animals
Fifty client-owned dogs that underwent intracranial surgery.

Methods
Records were searched... Read More about Postoperative survival and early complications after intracranial surgery in dogs.

Quantification of the effect of instrumentation error in objective gait assessment in the horse on hindlimb symmetry parameters (2018)
Journal Article
Serra Bragança, F., Rhodin, M., Wiestner, T., Hernlund, E., Pfau, T., Van Weeren, P. R., & Weishaupt, M. A. (2018). Quantification of the effect of instrumentation error in objective gait assessment in the horse on hindlimb symmetry parameters. Equine Veterinary Journal, 50(3), 370-376. https://doi.org/10.1111/evj.12766

Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States (2018)
Journal Article
Rajao, D. S., Anderson, T. K., Kitikoon, P., Stratton, J., Lewis, N. S., & Vincent, A. L. (2018). Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States. Virology, 518, 45-54. https://doi.org/10.1016/j.virol.2018.02.006

Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by transmission of IAV between swine and humans and subsequent evolution. Here, we characterized the genetic and antigeni... Read More about Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States.

Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease (2018)
Journal Article
Van Den Broek, D. H. N., Chang, Y. M., Elliott, J., & Jepson, R. E. (2018). Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease. Journal of Veterinary Internal Medicine, 32(4), 1359-1371. https://doi.org/10.1111/jvim.15141

Cost of porcine reproductive and respiratory syndrome virus at individual farm level – An economic disease model (2018)
Journal Article
Nathues, H., Alarcon, P., Rushton, J., Jolie, R., Fiebig, K., Jimenez, M., Geurts, V., & Nathues, C. (2018). Cost of porcine reproductive and respiratory syndrome virus at individual farm level – An economic disease model. Preventive Veterinary Medicine, 142, 16-29. https://doi.org/10.1016/j.prevetmed.2017.04.006

Porcine reproductive and respiratory syndrome (PRRS) is reported to be among the diseases with the highest economic impact in modern pig production worldwide. Yet, the economic impact of the disease at farm level is not well understood as, especially... Read More about Cost of porcine reproductive and respiratory syndrome virus at individual farm level – An economic disease model.

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response (2018)
Journal Article
Javaheri, B., Carriero, A., Wood, M., De Souza, R., Lee, P. D., Shefelbine, S., & Pitsillides, A. A. (2018). Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response. https://doi.org/10.1038/s41598-018-25084-6

Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimul... Read More about Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response.

Preliminary assessment of cognitive impairments in canine idiopathic epilepsy (2018)
Journal Article
Winter, J., Packer, R. M. A., & Volk, H. A. (2018). Preliminary assessment of cognitive impairments in canine idiopathic epilepsy. Veterinary Record, https://doi.org/10.1136/vr.104603

In humans, epilepsy can induce or accelerate cognitive impairment (CI). There is emerging evidence of CI in dogs with idiopathic epilepsy (IE) from recent epidemiological studies. The aim of our study was to assess CI in dogs with IE using two tests... Read More about Preliminary assessment of cognitive impairments in canine idiopathic epilepsy.

Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter (2018)
Journal Article
Read, J. E., Cabrera-Sharp, V., Kitscha, P., Cartwright, J. E., King, P. J., Fowkes, R. C., & De Mestre, A. M. (2018). Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter. Frontiers in Endocrinology, 9, https://doi.org/10.3389/fendo.2018.00195

Equine chorionic gonadotrophin (eCG) is a placental glycoprotein critical for early equine pregnancy and used therapeutically in a number of species to support reproductive activity. The factors in trophoblast that transcriptionally regulate eCGβ-sub... Read More about Glial Cells Missing 1 Regulates Equine Chorionic Gonadotrophin Beta Subunit via Binding to the Proximal Promoter.

Chromosome Segregation Is Biased by Kinetochore Size (2018)
Journal Article
Drpic, D., Almeida, A. C., Aguiar, P., Renda, F., Damas, J., Lewin, H. A., Larkin, D. M., Khodjakov, A., & Maiato, H. (2018). Chromosome Segregation Is Biased by Kinetochore Size. Current Biology, 28(9), 1344-1365. https://doi.org/10.1016/j.cub.2018.03.023

Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selectio... Read More about Chromosome Segregation Is Biased by Kinetochore Size.

Movement patterns and athletic performance of leopards in the Okavango Delta (2018)
Journal Article
Hubel, T. Y., Golabek, K. A., Rafiq, K., Weldon McNutt, J., & Wilson, A. M. (2018). Movement patterns and athletic performance of leopards in the Okavango Delta. Proceedings of the Royal Society B: Biological Sciences, 285(4), 1017-1027. https://doi.org/10.1098/rspb.2017.2622

Although leopards are the most widespread of all the big cats and are known for their adaptability, they are elusive and little is known in detail about their movement and hunting energetics. We used high-resolution GPS/IMU (inertial measurement unit... Read More about Movement patterns and athletic performance of leopards in the Okavango Delta.