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Prednisolone-induced diabetes mellitus in the cat: a historical cohort

Nerhagen, S; Moberg, HL; Boge, GS; Glanemann, B

Authors

S Nerhagen

HL Moberg

GS Boge

B Glanemann



Abstract

Objectives
Prednisolone is a commonly used drug in cats and potential adverse effects include hyperglycaemia and diabetes mellitus. The aims of this study were to evaluate the frequency and investigate potential predisposing risk factors for the development of prednisolone-induced diabetes mellitus (PIDM) in cats.

Methods
The electronic records of a tertiary referral centre were searched for cats receiving prednisolone at a starting dose of ⩾1.9 mg/kg/day, for >3 weeks and with follow-up data available for >3 months between January 2007 and July 2019. One hundred and forty-three cats were included in the study.

Results
Of the 143 cats, 14 cats (9.7%) were diagnosed with PIDM. Twelve out of 14 cats (85.7%) developed diabetes within 3 months of the initiation of therapy.

Conclusions and relevance
Cats requiring high-dose prednisolone therapy should be closely monitored over the first 3 months of therapy for the development of PIDM.

Citation

Nerhagen, S., Moberg, H., Boge, G., & Glanemann, B. (2020). Prednisolone-induced diabetes mellitus in the cat: a historical cohort. Journal of Feline Medicine and Surgery, 1098612X2094352. https://doi.org/10.1177/1098612x20943522

Journal Article Type Article
Acceptance Date Jun 18, 2020
Publication Date Jul 27, 2020
Deposit Date Aug 18, 2020
Publicly Available Date Aug 18, 2020
Journal Journal of Feline Medicine and Surgery
Print ISSN 1098-612X
Publisher Elsevier
Peer Reviewed Peer Reviewed
Pages 1098612X2094352
DOI https://doi.org/10.1177/1098612x20943522
Public URL https://rvc-repository.worktribe.com/output/1376609
Publisher URL https://doi.org/10.1177/1098612x20943522

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