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Nutritional Programming Effects on the Immune System

Palmer, D B


D B Palmer


P C Guest


The relationship between patterns of early growth and age-associated diseases such as type 2 diabetes and cardiovascular disease is well established. There is also strong evidence from both human and animal studies that early environmental factors such as maternal nutrition may influence lifespan. Interestingly, more recent studies have demonstrated that nutritional programming in early life effects immunity, such that altered lifespan can also lead to programmed changes in immune function. Here we describe the use of immunohistology and flow cytometry techniques to study two key immune lymphoid organs: one that is involved in developing immune cells (thymus) and another which is the site of immune activation (spleen).


Palmer, D. B. Nutritional Programming Effects on the Immune System

Journal Article Type Article
Deposit Date Jun 13, 2019
Journal Methods in Molecular Biology
Volume 1735
Pages 311-319
Book Title Investigations of Early Nutrition Effects on Long-Term Health
ISBN 978-1-4939-7614-0
Public URL